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Murcko scaffold

Ring system with 3 rings and 18 atoms

81 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
81
With full pages
15
Scaffold SMILES

O=C(Nc1ccc2[nH]cnc2c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc2[nH]cnc2c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 81 of 81 chemicals

2-Methoxy-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide chemical structure, C18H19N3O2, CAS 1219556-83-8
2-Methoxy-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide
CAS 1219556-83-8C18H19N3O2
N-(1H-Benzimidazol-5-yl)-3-methoxybenzamide chemical structure, C15H13N3O2, CAS 1219538-98-3
N-(1H-Benzimidazol-5-yl)-3-methoxybenzamide
CAS 1219538-98-3C15H13N3O2
4-Fluoro-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide chemical structure, C17H16FN3O, CAS 1219543-10-8
4-Fluoro-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide
CAS 1219543-10-8C17H16FN3O
N-(1H-Benzimidazol-5-yl)-3-bromobenzamide chemical structure, C14H10BrN3O, CAS 1219569-90-0
N-(1H-Benzimidazol-5-yl)-3-bromobenzamide
CAS 1219569-90-0C14H10BrN3O
2,4-Dichloro-N-(2-methyl-1H-benzimidazol-5-yl)benzamide chemical structure, C15H11Cl2N3O, CAS 1219580-67-2
2,4-Dichloro-N-(2-methyl-1H-benzimidazol-5-yl)benzamide
CAS 1219580-67-2C15H11Cl2N3O
N-(1H-Benzimidazol-5-yl)-3-chlorobenzamide chemical structure, C14H10ClN3O, CAS 1219569-62-6
N-(1H-Benzimidazol-5-yl)-3-chlorobenzamide
CAS 1219569-62-6C14H10ClN3O
N-(1H-Benzimidazol-5-yl)-3,4,5-trimethoxybenzamide chemical structure, C17H17N3O4, CAS 1219558-65-2
N-(1H-Benzimidazol-5-yl)-3,4,5-trimethoxybenzamide
CAS 1219558-65-2C17H17N3O4
2-Chloro-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide chemical structure, C17H16ClN3O, CAS 1219583-25-1
2-Chloro-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide
CAS 1219583-25-1C17H16ClN3O
N-(1H-Benzimidazol-5-yl)-2,4-dichlorobenzamide chemical structure, C14H9Cl2N3O, CAS 1219562-04-5
N-(1H-Benzimidazol-5-yl)-2,4-dichlorobenzamide
CAS 1219562-04-5C14H9Cl2N3O
3,4-Dimethoxy-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C17H14F3N3O3, CAS 1219575-91-3
3,4-Dimethoxy-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1219575-91-3C17H14F3N3O3
2-Fluoro-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide chemical structure, C17H16FN3O, CAS 1219568-75-8
2-Fluoro-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide
CAS 1219568-75-8C17H16FN3O
3,5-Dimethoxy-N-(2-methyl-1H-benzimidazol-5-yl)benzamide chemical structure, C17H17N3O3, CAS 1219588-86-9
3,5-Dimethoxy-N-(2-methyl-1H-benzimidazol-5-yl)benzamide
CAS 1219588-86-9C17H17N3O3
3,4-Dimethoxy-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide chemical structure, C19H21N3O3, CAS 1219572-61-8
3,4-Dimethoxy-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]benzamide
CAS 1219572-61-8C19H21N3O3
3-Bromo-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H14BrN3O2, CAS 1232782-56-7
3-Bromo-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232782-56-7C16H14BrN3O2
4-Chloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H14ClN3O2, CAS 1232804-64-6
4-Chloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232804-64-6C16H14ClN3O2
3-Chloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H14ClN3O2, CAS 1224170-21-1
3-Chloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1224170-21-1C16H14ClN3O2
3,5-Dimethoxy-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C18H19N3O4, CAS 1224169-96-3
3,5-Dimethoxy-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1224169-96-3C18H19N3O4
2-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H14FN3O2, CAS 1232779-69-9
2-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232779-69-9C16H14FN3O2
4-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H14FN3O2, CAS 1232779-80-4
4-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232779-80-4C16H14FN3O2
3-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H14FN3O2, CAS 1232802-09-3
3-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232802-09-3C16H14FN3O2
2,4-Dichloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H13Cl2N3O2, CAS 1224129-33-2
2,4-Dichloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1224129-33-2C16H13Cl2N3O2
3,4,5-Trimethoxy-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C19H21N3O5, CAS 1232779-77-9
3,4,5-Trimethoxy-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232779-77-9C19H21N3O5
3,4,5-Trimethoxy-N-(2-methyl-1H-benzimidazol-5-yl)benzamide chemical structure, C18H19N3O4, CAS 1224168-65-3
3,4,5-Trimethoxy-N-(2-methyl-1H-benzimidazol-5-yl)benzamide
CAS 1224168-65-3C18H19N3O4
3,4-Dichloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H13Cl2N3O2, CAS 1232785-23-7
3,4-Dichloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1232785-23-7C16H13Cl2N3O2