CompoundList
Sign in
Murcko scaffold

5,6,7,8-Tetrahydroquinazoline scaffold

255 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
255
With full pages
34
Scaffold SMILES

c1ncc2c(n1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydroquinazoline page
Murcko scaffold c1ncc2c(n1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 255 chemicals

5,6,7,8-Tetrahydroquinazoline-2,4-diamine chemical structure, C8H12N4, CAS 1899-40-7
5,6,7,8-Tetrahydroquinazoline-2,4-diamine
CAS 1899-40-7C8H12N4
1-[2,4-Bis(phenylmethoxy)phenyl]-2-methoxyethanone chemical structure, C9H11N3O2, CAS 51640-97-2
1-[2,4-Bis(phenylmethoxy)phenyl]-2-methoxyethanone
CAS 51640-97-2C9H11N3O2
5,6,7,8-Tetrahydroquinazolin-2-amine chemical structure, C8H11N3, CAS 2305-85-3
5,6,7,8-Tetrahydroquinazolin-2-amine
CAS 2305-85-3C8H11N3
2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid chemical structure, C9H12N4O2, CAS 6974-25-0
2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid
CAS 6974-25-0C9H12N4O2
2,4-Dichloro-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid chemical structure, C9H8Cl2N2O2, CAS 5458-56-0
2,4-Dichloro-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid
CAS 5458-56-0C9H8Cl2N2O2
2,4-Dichloro-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid diethylamide chemical structure, C13H17Cl2N3O, CAS 100608-07-9
2,4-Dichloro-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid diethylamide
CAS 100608-07-9C13H17Cl2N3O
2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide chemical structure, C9H13N5O, CAS 5466-45-5
2,4-Diamino-5,6,7,8-tetrahydroquinazoline-6-carboxamide
CAS 5466-45-5C9H13N5O
2,4-Dichloro-5,6,7,8-tetrahydroquinazoline-6-carbonitrile chemical structure, C9H7Cl2N3, CAS 100245-95-2
2,4-Dichloro-5,6,7,8-tetrahydroquinazoline-6-carbonitrile
CAS 100245-95-2C9H7Cl2N3
2-Methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H12N2, CAS 6299-01-0
2-Methyl-5,6,7,8-tetrahydroquinazoline
CAS 6299-01-0C9H12N2
N-[2-Acetamido-6-(dimethoxymethyl)-5,6,7,8-tetrahydroquinazolin-4-yl]acetamide chemical structure, C15H22N4O4, CAS 94251-70-4
N-[2-Acetamido-6-(dimethoxymethyl)-5,6,7,8-tetrahydroquinazolin-4-yl]acetamide
CAS 94251-70-4C15H22N4O4
N-(2-Acetamido-6-formyl-5,6,7,8-tetrahydroquinazolin-4-yl)acetamide chemical structure, C13H16N4O3, CAS 6950-52-3
N-(2-Acetamido-6-formyl-5,6,7,8-tetrahydroquinazolin-4-yl)acetamide
CAS 6950-52-3C13H16N4O3
5,6,7,8-Tetrahydroquinazoline chemical structure, C8H10N2, CAS 5632-33-7
5,6,7,8-Tetrahydroquinazoline
CAS 5632-33-7C8H10N2
4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C9H10F3N3, CAS 256954-38-8
4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 256954-38-8C9H10F3N3
1-(4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl)thiourea chemical structure, C10H11F3N4S, CAS 318258-27-4
1-(4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl)thiourea
CAS 318258-27-4C10H11F3N4S
2-(Methylsulfanyl)-5,6,7,8-tetrahydro-4-quinazolinyl pivalate chemical structure, C14H20N2O2S, CAS 303987-60-2
2-(Methylsulfanyl)-5,6,7,8-tetrahydro-4-quinazolinyl pivalate
CAS 303987-60-2C14H20N2O2S
Methyl [(4-methyl-5,6,7,8-tetrahydroquinazolin-2-yl)sulfanyl]acetate chemical structure, C12H16N2O2S, CAS 578003-19-7
Methyl [(4-methyl-5,6,7,8-tetrahydroquinazolin-2-yl)sulfanyl]acetate
CAS 578003-19-7C12H16N2O2S
4-Methyl-2-prop-2-ynylsulfanyl-5,6,7,8-tetrahydroquinazoline chemical structure, C12H14N2S, CAS 573932-16-8
4-Methyl-2-prop-2-ynylsulfanyl-5,6,7,8-tetrahydroquinazoline
CAS 573932-16-8C12H14N2S
2-Methylsulfonyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C10H11F3N2O2S, CAS 892254-08-9
2-Methylsulfonyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline
CAS 892254-08-9C10H11F3N2O2S
Diethyl 2,2'-((5,6,7,8-tetrahydroquinazoline-2,4-diyl)bis(sulfanediyl))diacetate chemical structure, C16H22N2O4S2, CAS 1165-85-1
Diethyl 2,2'-((5,6,7,8-tetrahydroquinazoline-2,4-diyl)bis(sulfanediyl))diacetate
CAS 1165-85-1C16H22N2O4S2
2-{[4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]sulfanyl}acetic acid chemical structure, C11H11F3N2O2S, CAS 380389-18-4
2-{[4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]sulfanyl}acetic acid
CAS 380389-18-4C11H11F3N2O2S
4-Chloro-2-(methylthio)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H11ClN2S, CAS 51660-11-8
4-Chloro-2-(methylthio)-5,6,7,8-tetrahydroquinazoline
CAS 51660-11-8C9H11ClN2S
2-[(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)sulfanyl]acetic acid chemical structure, C11H14N2O2S, CAS 852537-88-3
2-[(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)sulfanyl]acetic acid
CAS 852537-88-3C11H14N2O2S
4-Methyl-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C9H13N3, CAS 58544-43-7
4-Methyl-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 58544-43-7C9H13N3
2-[(5,6,7,8-Tetrahydro-4-quinazolinyl)thio]acetic acid chemical structure, C10H12N2O2S, CAS 1136-88-5
2-[(5,6,7,8-Tetrahydro-4-quinazolinyl)thio]acetic acid
CAS 1136-88-5C10H12N2O2S