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Murcko scaffold

5,6,7,8-Tetrahydroquinazoline scaffold

255 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
255
With full pages
34
Scaffold SMILES

c1ncc2c(n1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydroquinazoline page
Murcko scaffold c1ncc2c(n1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 255 chemicals

6-Acetylamino-5,6,7,8-tetrahydro-2-thioureidoquinazoline chemical structure, C11H15N5OS, CAS 1284229-29-3
6-Acetylamino-5,6,7,8-tetrahydro-2-thioureidoquinazoline
CAS 1284229-29-3C11H15N5OS
5,6,7,8-Tetrahydroquinazolin-5-amine chemical structure, C8H11N3, CAS 927803-65-4
5,6,7,8-Tetrahydroquinazolin-5-amine
CAS 927803-65-4C8H11N3
2-(5-Amino-5,6,7,8-tetrahydroquinazolin-2-yl)ethanol chemical structure, C10H15N3O, CAS 883997-66-8
2-(5-Amino-5,6,7,8-tetrahydroquinazolin-2-yl)ethanol
CAS 883997-66-8C10H15N3O
tert-Butyl N-(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)carbamate chemical structure, C13H20N4O2, CAS 1073633-86-9
tert-Butyl N-(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)carbamate
CAS 1073633-86-9C13H20N4O2
4-Chloro-2-(chloromethyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H10Cl2N2, CAS 1533769-90-2
4-Chloro-2-(chloromethyl)-5,6,7,8-tetrahydroquinazoline
CAS 1533769-90-2C9H10Cl2N2
2-(tert-Butyl)-5,6,7,8-tetrahydro-5-quinazolinamine chemical structure, C12H19N3, CAS 927803-67-6
2-(tert-Butyl)-5,6,7,8-tetrahydro-5-quinazolinamine
CAS 927803-67-6C12H19N3
6-Methyl-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C9H13N3, CAS 704-62-1
6-Methyl-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 704-62-1C9H13N3
N-Methyl-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C9H13N3, CAS 1343504-56-2
N-Methyl-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 1343504-56-2C9H13N3
6,6-Dimethyl-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C10H15N3, CAS 1344202-33-0
6,6-Dimethyl-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 1344202-33-0C10H15N3
6-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C9H10F3N3, CAS 1342853-24-0
6-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 1342853-24-0C9H10F3N3
2,4-Dichloro-5,7-dimethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C10H12Cl2N2, CAS 1484482-18-9
2,4-Dichloro-5,7-dimethyl-5,6,7,8-tetrahydroquinazoline
CAS 1484482-18-9C10H12Cl2N2
2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C10H12Cl2N2, CAS 1480939-99-8
2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline
CAS 1480939-99-8C10H12Cl2N2
2,4-Dichloro-6-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H10Cl2N2, CAS 1465063-86-8
2,4-Dichloro-6-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1465063-86-8C9H10Cl2N2
5,6,7,8-Tetrahydroquinazolin-2-ylmethanol chemical structure, C9H12N2O, CAS 1378665-98-5
5,6,7,8-Tetrahydroquinazolin-2-ylmethanol
CAS 1378665-98-5C9H12N2O
2-Methyl-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid chemical structure, C10H12N2O2, CAS 1368072-02-9
2-Methyl-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid
CAS 1368072-02-9C10H12N2O2
2-Methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid hydrochloride chemical structure, C11H12ClF3N2O2, CAS 1384707-94-1
2-Methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid hydrochloride
CAS 1384707-94-1C11H12ClF3N2O2
2-Methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid chemical structure, C11H11F3N2O2, CAS 1384782-74-4
2-Methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid
CAS 1384782-74-4C11H11F3N2O2
(5,6,7,8-Tetrahydroquinazolin-2-yl)methanol hydrochloride chemical structure, C9H13ClN2O, CAS 1427379-82-5
(5,6,7,8-Tetrahydroquinazolin-2-yl)methanol hydrochloride
CAS 1427379-82-5C9H13ClN2O
2-[4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]ethan-1-amine chemical structure, C11H14F3N3, CAS 1000560-93-9
2-[4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]ethan-1-amine
CAS 1000560-93-9C11H14F3N3
2-(4-Trifluoromethyl-5,6,7,8-tetrahydro-quinazolin-2-yl)-ethylamine hydrochloride chemical structure, C11H15ClF3N3, CAS 1421532-68-4
2-(4-Trifluoromethyl-5,6,7,8-tetrahydro-quinazolin-2-yl)-ethylamine hydrochloride
CAS 1421532-68-4C11H15ClF3N3
2-Methyl-5,6,7,8-tetrahydroquinazoline-6-carbaldehyde chemical structure, C10H12N2O, CAS 956723-18-5
2-Methyl-5,6,7,8-tetrahydroquinazoline-6-carbaldehyde
CAS 956723-18-5C10H12N2O
2-(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)ethanamine dihydrochloride chemical structure, C11H19Cl2N3, CAS 1609402-92-7
2-(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)ethanamine dihydrochloride
CAS 1609402-92-7C11H19Cl2N3
4-Methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H12N2, CAS 103796-40-3
4-Methyl-5,6,7,8-tetrahydroquinazoline
CAS 103796-40-3C9H12N2
[(4-Chloro-5,6,7,8-tetrahydroquinazolin-2-yl)methyl]dimethylamine chemical structure, C11H16ClN3, CAS 1499627-35-8
[(4-Chloro-5,6,7,8-tetrahydroquinazolin-2-yl)methyl]dimethylamine
CAS 1499627-35-8C11H16ClN3