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Murcko scaffold

5,6,7,8-Tetrahydroquinazoline scaffold

255 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
255
With full pages
34
Scaffold SMILES

c1ncc2c(n1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydroquinazoline page
Murcko scaffold c1ncc2c(n1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 255 chemicals

1-(4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)-N,N-dimethylethanamine chemical structure, C14H22ClN3, CAS 1256958-12-9
1-(4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)-N,N-dimethylethanamine
CAS 1256958-12-9C14H22ClN3
4-Chloro-2,6,6-trimethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C11H15ClN2, CAS 1256955-93-7
4-Chloro-2,6,6-trimethyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-93-7C11H15ClN2
N-((4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)methyl)methanesulfonamide chemical structure, C12H18ClN3O2S, CAS 1256956-52-1
N-((4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)methyl)methanesulfonamide
CAS 1256956-52-1C12H18ClN3O2S
(r)-4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H11ClN2, CAS 1256955-44-8
(r)-4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-44-8C9H11ClN2
4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H11ClN2, CAS 1256955-90-4
4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-90-4C9H11ClN2
4-Chloro-6-ethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C10H13ClN2, CAS 1256955-91-5
4-Chloro-6-ethyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-91-5C10H13ClN2
4-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H8ClF3N2, CAS 1256784-33-4
4-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline
CAS 1256784-33-4C9H8ClF3N2
4-Chloro-7,7-dimethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C10H13ClN2, CAS 1256955-41-5
4-Chloro-7,7-dimethyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-41-5C10H13ClN2
4-Chloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline chemical structure, C8H7ClF2N2, CAS 1256955-43-7
4-Chloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline
CAS 1256955-43-7C8H7ClF2N2
4-Chloro-2,6-dimethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C10H13ClN2, CAS 1256955-45-9
4-Chloro-2,6-dimethyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-45-9C10H13ClN2
4-Chloro-6-ethyl-2-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C11H15ClN2, CAS 1256955-46-0
4-Chloro-6-ethyl-2-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-46-0C11H15ClN2
N-((4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)methyl)-N-methylpropan-2-amine chemical structure, C15H24ClN3, CAS 1256956-21-4
N-((4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)methyl)-N-methylpropan-2-amine
CAS 1256956-21-4C15H24ClN3
4-Chloro-8,8-dimethyl-5,6,7,8-tetrahydroquinazoline chemical structure, C10H13ClN2, CAS 1256955-52-8
4-Chloro-8,8-dimethyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-52-8C10H13ClN2
4-Chloro-5-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H8ClF3N2, CAS 1256955-50-6
4-Chloro-5-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline
CAS 1256955-50-6C9H8ClF3N2
4-Chloro-7-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H8ClF3N2, CAS 1256955-47-1
4-Chloro-7-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline
CAS 1256955-47-1C9H8ClF3N2
4-Chloro-6-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H11ClN2, CAS 1256958-75-4
4-Chloro-6-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1256958-75-4C9H11ClN2
(s)-4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H11ClN2, CAS 1256955-49-3
(s)-4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1256955-49-3C9H11ClN2
4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-amine chemical structure, C10H14ClN3, CAS 1141891-15-7
4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-amine
CAS 1141891-15-7C10H14ClN3
2-Bromo-5,6,7,8-tetrahydroquinazoline chemical structure, C8H9BrN2, CAS 1379363-97-9
2-Bromo-5,6,7,8-tetrahydroquinazoline
CAS 1379363-97-9C8H9BrN2
N-(2-Methyl-5,6,7,8-tetrahydro-quinazolin-6-yl)-acetamide chemical structure, C11H15N3O, CAS 1628517-80-5
N-(2-Methyl-5,6,7,8-tetrahydro-quinazolin-6-yl)-acetamide
CAS 1628517-80-5C11H15N3O
N-(5,6,7,8-Tetrahydroquinazolin-6-yl)acetamide chemical structure, C10H13N3O, CAS 1628517-81-6
N-(5,6,7,8-Tetrahydroquinazolin-6-yl)acetamide
CAS 1628517-81-6C10H13N3O
5,6,7,8-Tetrahydro-2-iodo-4-(trifluoromethyl)quinazoline chemical structure, C9H8F3IN2, CAS 1820736-31-9
5,6,7,8-Tetrahydro-2-iodo-4-(trifluoromethyl)quinazoline
CAS 1820736-31-9C9H8F3IN2
[5,6,7,8-Tetrahydro-4-(trifluoromethyl)quinazolin-2-yl]phosphonic acid diethyl ester chemical structure, C13H18F3N2O3P, CAS 1820605-00-2
[5,6,7,8-Tetrahydro-4-(trifluoromethyl)quinazolin-2-yl]phosphonic acid diethyl ester
CAS 1820605-00-2C13H18F3N2O3P
2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(triflioromethyl)quinazoline chemical structure, C10H12F3N3, CAS 1822873-63-1
2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(triflioromethyl)quinazoline
CAS 1822873-63-1C10H12F3N3