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Murcko scaffold

5,6,7,8-Tetrahydroquinazoline scaffold

255 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
255
With full pages
34
Scaffold SMILES

c1ncc2c(n1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydroquinazoline page
Murcko scaffold c1ncc2c(n1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 255 chemicals

tert-Butyl (2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)carbamate chemical structure, C14H21N3O2, CAS 1440526-43-1
tert-Butyl (2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)carbamate
CAS 1440526-43-1C14H21N3O2
tert-Butyl (5,6,7,8-tetrahydroquinazolin-6-yl)carbamate chemical structure, C13H19N3O2, CAS 1440526-58-8
tert-Butyl (5,6,7,8-tetrahydroquinazolin-6-yl)carbamate
CAS 1440526-58-8C13H19N3O2
4-(Prop-2-en-1-yloxy)-5,6,7,8-tetrahydroquinazoline chemical structure, C11H14N2O, CAS 2168726-05-2
4-(Prop-2-en-1-yloxy)-5,6,7,8-tetrahydroquinazoline
CAS 2168726-05-2C11H14N2O
4-(2,2-Difluoroethoxy)-5,6,7,8-tetrahydroquinazoline chemical structure, C10H12F2N2O, CAS 2197878-06-9
4-(2,2-Difluoroethoxy)-5,6,7,8-tetrahydroquinazoline
CAS 2197878-06-9C10H12F2N2O
2-Amino-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid ethyl ester chemical structure, C11H15N3O2, CAS 1359655-66-5
2-Amino-5,6,7,8-tetrahydro-quinazoline-6-carboxylic acid ethyl ester
CAS 1359655-66-5C11H15N3O2
5,6,7,8-Tetrahydroquinazoline-5-carboxylic acid chemical structure, C9H10N2O2, CAS 1823920-30-4
5,6,7,8-Tetrahydroquinazoline-5-carboxylic acid
CAS 1823920-30-4C9H10N2O2
2-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H8ClF3N2, CAS 1861547-86-5
2-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline
CAS 1861547-86-5C9H8ClF3N2
2-Chloro-6,6-dimethyl-7,8-dihydro-5H-quinazoline chemical structure, C10H13ClN2, CAS 1866839-90-8
2-Chloro-6,6-dimethyl-7,8-dihydro-5H-quinazoline
CAS 1866839-90-8C10H13ClN2
4-(Methylsulfanyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C9H12N2S, CAS 1127-77-1
4-(Methylsulfanyl)-5,6,7,8-tetrahydroquinazoline
CAS 1127-77-1C9H12N2S
2-Chloro-6-methyl-5,6,7,8-tetrahydroquinazoline chemical structure, C9H11ClN2, CAS 1866824-91-0
2-Chloro-6-methyl-5,6,7,8-tetrahydroquinazoline
CAS 1866824-91-0C9H11ClN2
2-Quinazolinemethanamine, 5,6,7,8-tetrahydro-4-(trifluoromethyl)- chemical structure, C10H12F3N3, CAS 1822851-55-7
2-Quinazolinemethanamine, 5,6,7,8-tetrahydro-4-(trifluoromethyl)-
CAS 1822851-55-7C10H12F3N3
N-(2-Chloro-5,6,7,8-tetrahydroquinazolin-6-yl)acetamide chemical structure, C10H12ClN3O, CAS 1628517-82-7
N-(2-Chloro-5,6,7,8-tetrahydroquinazolin-6-yl)acetamide
CAS 1628517-82-7C10H12ClN3O
(2,4-Dichloro-5,6,7,8-tetrahydroquinazolin-6-yl)methanol chemical structure, C9H10Cl2N2O, CAS 109047-30-5
(2,4-Dichloro-5,6,7,8-tetrahydroquinazolin-6-yl)methanol
CAS 109047-30-5C9H10Cl2N2O
N-(2-Methyl-5,6,7,8-tetrahydroquinazolin-6-yl)prop-2-enamide chemical structure, C12H15N3O, CAS 2196075-65-5
N-(2-Methyl-5,6,7,8-tetrahydroquinazolin-6-yl)prop-2-enamide
CAS 2196075-65-5C12H15N3O
2-Chloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline chemical structure, C8H7ClF2N2, CAS 2002287-57-0
2-Chloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline
CAS 2002287-57-0C8H7ClF2N2
N-(2-Methyl-5,6,7,8-tetrahydroquinazolin-5-yl)prop-2-enamide chemical structure, C12H15N3O, CAS 2224407-86-5
N-(2-Methyl-5,6,7,8-tetrahydroquinazolin-5-yl)prop-2-enamide
CAS 2224407-86-5C12H15N3O
tert-Butyl N-(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)-N-methylcarbamate chemical structure, C14H22N4O2, CAS 2309460-05-5
tert-Butyl N-(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)-N-methylcarbamate
CAS 2309460-05-5C14H22N4O2
Methyl 2,4-dichloro-5,6,7,8-tetrahydroquinazoline-6-carboxylate chemical structure, C10H10Cl2N2O2, CAS 1208124-19-9
Methyl 2,4-dichloro-5,6,7,8-tetrahydroquinazoline-6-carboxylate
CAS 1208124-19-9C10H10Cl2N2O2
Ethyl 5,6,7,8-tetrahydroquinazoline-4-carboxylate chemical structure, C11H14N2O2, CAS 2110345-21-4
Ethyl 5,6,7,8-tetrahydroquinazoline-4-carboxylate
CAS 2110345-21-4C11H14N2O2
4-Chloro-2-ethylsulfanyl-8,8-difluoro-6,7-dihydro-5H-quinazoline chemical structure, C10H11ClF2N2S, CAS 338740-20-8
4-Chloro-2-ethylsulfanyl-8,8-difluoro-6,7-dihydro-5H-quinazoline
CAS 338740-20-8C10H11ClF2N2S
2,4-Dichloro-6-methyl-7,8-dihydro-5H-quinazolin-6-ol chemical structure, C9H10Cl2N2O, CAS 1312934-93-2
2,4-Dichloro-6-methyl-7,8-dihydro-5H-quinazolin-6-ol
CAS 1312934-93-2C9H10Cl2N2O
2,4-Dichloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline chemical structure, C8H6Cl2F2N2, CAS 1312934-50-1
2,4-Dichloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline
CAS 1312934-50-1C8H6Cl2F2N2
2,4-Dichloro-5,6,7,8-tetrahydroquinazolin-8-ol chemical structure, C8H8Cl2N2O, CAS 1312934-58-9
2,4-Dichloro-5,6,7,8-tetrahydroquinazolin-8-ol
CAS 1312934-58-9C8H8Cl2N2O
N-Methyl-N-{[(2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)carbamoyl]methyl}prop-2-enamide chemical structure, C15H20N4O2, CAS 2197609-62-2
N-Methyl-N-{[(2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)carbamoyl]methyl}prop-2-enamide
CAS 2197609-62-2C15H20N4O2