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Murcko scaffold

5-Oxo-1-phenyl-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
13
With full pages
3
Scaffold SMILES

O=C(NCc1cccnc1)C1CC(=O)N(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Oxo-1-phenyl-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide page
Murcko scaffold O=C(NCc1cccnc1)C1CC(=O)N(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

1-(4-Fluorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H16FN3O2, CAS 440109-26-2
1-(4-Fluorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 440109-26-2C17H16FN3O2
1-(4-Chlorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H16ClN3O2, CAS 364744-26-3
1-(4-Chlorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 364744-26-3C17H16ClN3O2
1-(4-Isopropyl-3-methylphenyl)-5-oxo-N-(3-pyridinylmethyl)-3-pyrrolidinecarboxamide chemical structure, C21H25N3O2, CAS 866153-55-1
1-(4-Isopropyl-3-methylphenyl)-5-oxo-N-(3-pyridinylmethyl)-3-pyrrolidinecarboxamide
CAS 866153-55-1C21H25N3O2
1-(4-Ethoxyphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C19H21N3O3, CAS 878431-60-8
1-(4-Ethoxyphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 878431-60-8C19H21N3O3
1-(3-Chloro-4-methylphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C18H18ClN3O2, CAS 887674-68-2
1-(3-Chloro-4-methylphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 887674-68-2C18H18ClN3O2
5-Oxo-1-phenyl-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H17N3O2, CAS 879581-64-3
5-Oxo-1-phenyl-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 879581-64-3C17H17N3O2
1-(4-Ethylphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C19H21N3O2, CAS 897736-93-5
1-(4-Ethylphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 897736-93-5C19H21N3O2
1-(3-Chloro-4-fluorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H15ClFN3O2, CAS 945321-54-0
1-(3-Chloro-4-fluorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 945321-54-0C17H15ClFN3O2
1-(3-Chloro-4-methoxyphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C18H18ClN3O3, CAS 1010910-74-3
1-(3-Chloro-4-methoxyphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 1010910-74-3C18H18ClN3O3
5-Oxo-N-(pyridin-3-ylmethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide chemical structure, C18H16F3N3O2, CAS 1010932-10-1
5-Oxo-N-(pyridin-3-ylmethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide
CAS 1010932-10-1C18H16F3N3O2
1-(3-Chlorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H16ClN3O2, CAS 1144430-90-9
1-(3-Chlorophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 1144430-90-9C17H16ClN3O2
1-(2,6-Dimethylphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C19H21N3O2, CAS 1185384-55-7
1-(2,6-Dimethylphenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 1185384-55-7C19H21N3O2
1-(4-Bromophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H16BrN3O2, CAS 1190263-19-4
1-(4-Bromophenyl)-5-oxo-N-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
CAS 1190263-19-4C17H16BrN3O2