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Murcko scaffold

Ring system with 2 rings and 15 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
19
With full pages
3
Scaffold SMILES

O=C(CCc1ccccc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

LG 83-6-05 chemical structure, C21H29NO3S, CAS 131602-24-9
LG 83-6-05
CAS 131602-24-9C21H29NO3S
3-(3-Chlorophenyl)-1-(2-thienyl)-1-propanone chemical structure, C13H11ClOS, CAS 685108-38-7
3-(3-Chlorophenyl)-1-(2-thienyl)-1-propanone
CAS 685108-38-7C13H11ClOS
Dimethyl 2-[1-(3-chlorophenyl)-3-oxo-3-(2-thienyl)propyl]malonate chemical structure, C18H17ClO5S, CAS 860650-17-5
Dimethyl 2-[1-(3-chlorophenyl)-3-oxo-3-(2-thienyl)propyl]malonate
CAS 860650-17-5C18H17ClO5S
Dimethyl 2-[1-(2-methoxyphenyl)-3-oxo-3-(2-thienyl)propyl]malonate chemical structure, C19H20O6S, CAS 685108-45-6
Dimethyl 2-[1-(2-methoxyphenyl)-3-oxo-3-(2-thienyl)propyl]malonate
CAS 685108-45-6C19H20O6S
3-(2-Methoxyphenyl)-1-(2-thienyl)-1-propanone chemical structure, C14H14O2S, CAS 685108-47-8
3-(2-Methoxyphenyl)-1-(2-thienyl)-1-propanone
CAS 685108-47-8C14H14O2S
[1-(2-Chlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl]propanedinitrile chemical structure, C16H11ClN2OS, CAS 82137-58-4
[1-(2-Chlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl]propanedinitrile
CAS 82137-58-4C16H11ClN2OS
[1-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl]propanedinitrile chemical structure, C16H10Cl2N2OS, CAS 400737-44-2
[1-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl]propanedinitrile
CAS 400737-44-2C16H10Cl2N2OS
[1-(2,4-Dimethylphenyl)-3-oxo-3-(2-thienyl)propyl]malononitrile chemical structure, C18H16N2OS, CAS 412944-77-5
[1-(2,4-Dimethylphenyl)-3-oxo-3-(2-thienyl)propyl]malononitrile
CAS 412944-77-5C18H16N2OS
4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one chemical structure, C14H11F3O2S, CAS 146801-21-0
4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one
CAS 146801-21-0C14H11F3O2S
2-(3-Oxo-1-phenyl-3-thiophen-2-ylpropyl)propanedinitrile chemical structure, C16H12N2OS, CAS 81829-55-2
2-(3-Oxo-1-phenyl-3-thiophen-2-ylpropyl)propanedinitrile
CAS 81829-55-2C16H12N2OS
LG 6-101 chemical structure, C22H32ClNO3S, CAS 132798-26-6
LG 6-101
CAS 132798-26-6C22H32ClNO3S
2-[1-(4-Chlorophenyl)-3-oxo-3-thiophen-2-ylpropyl]propanedinitrile chemical structure, C16H11ClN2OS, CAS 82137-59-5
2-[1-(4-Chlorophenyl)-3-oxo-3-thiophen-2-ylpropyl]propanedinitrile
CAS 82137-59-5C16H11ClN2OS
2-(3-(5-Chloro-2-thienyl)-1-(2,6-dichlorophenyl)-3-oxopropyl)malononitrile chemical structure, C16H9Cl3N2OS, CAS 302904-32-1
2-(3-(5-Chloro-2-thienyl)-1-(2,6-dichlorophenyl)-3-oxopropyl)malononitrile
CAS 302904-32-1C16H9Cl3N2OS
3-(3,4-Dimethoxyphenyl)-3-[(2-hydroxyethyl)sulfanyl]-1-(thiophen-2-yl)propan-1-one chemical structure, C17H20O4S2, CAS 315697-48-4
3-(3,4-Dimethoxyphenyl)-3-[(2-hydroxyethyl)sulfanyl]-1-(thiophen-2-yl)propan-1-one
CAS 315697-48-4C17H20O4S2
2-(1-(4-Chlorophenyl)-3-(5-chloro-2-thienyl)-3-oxopropyl)malononitrile chemical structure, C16H10Cl2N2OS, CAS 302904-33-2
2-(1-(4-Chlorophenyl)-3-(5-chloro-2-thienyl)-3-oxopropyl)malononitrile
CAS 302904-33-2C16H10Cl2N2OS
2-[3-(5-Chloro-2-thienyl)-3-oxo-1-phenylpropyl]propanedinitrile chemical structure, C16H11ClN2OS, CAS 188782-72-1
2-[3-(5-Chloro-2-thienyl)-3-oxo-1-phenylpropyl]propanedinitrile
CAS 188782-72-1C16H11ClN2OS
Ethyl 3-(5-chloro-2-thienyl)-3-oxo-2-[4-(trifluoromethyl)benzyl]propionate chemical structure, C17H14ClF3O3S, CAS 444917-00-4
Ethyl 3-(5-chloro-2-thienyl)-3-oxo-2-[4-(trifluoromethyl)benzyl]propionate
CAS 444917-00-4C17H14ClF3O3S
3-(4-Hydroxy-3,5-dimethyl-phenyl)-1-(5-isobutyl-thiophen-2-yl)-propan-1-one chemical structure, C19H24O2S, CAS 1010113-78-6
3-(4-Hydroxy-3,5-dimethyl-phenyl)-1-(5-isobutyl-thiophen-2-yl)-propan-1-one
CAS 1010113-78-6C19H24O2S
3-(4-Chlorophenyl)-1-(2-thienyl)-1-propanone chemical structure, C13H11ClOS, CAS 874009-13-9
3-(4-Chlorophenyl)-1-(2-thienyl)-1-propanone
CAS 874009-13-9C13H11ClOS