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Murcko scaffold

Ring system with 3 rings and 22 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
16
With full pages
4
Scaffold SMILES

O=C(NCc1ccccc1)c1ccc2c(=O)[nH]c(=S)[nH]c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)c1ccc2c(=O)[nH]c(=S)[nH]c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-[(2-Methoxyphenyl)methyl]-4-oxo-3-propyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C20H21N3O3S, CAS 403727-92-4
N-[(2-Methoxyphenyl)methyl]-4-oxo-3-propyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 403727-92-4C20H21N3O3S
N-[(3,4-Dichlorophenyl)methyl]-3-(2-methoxyethyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C19H17Cl2N3O3S, CAS 422529-44-0
N-[(3,4-Dichlorophenyl)methyl]-3-(2-methoxyethyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 422529-44-0C19H17Cl2N3O3S
N-Benzyl-3-(2-(diethylamino)ethyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H26N4O2S, CAS 422528-75-4
N-Benzyl-3-(2-(diethylamino)ethyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 422528-75-4C22H26N4O2S
3-(2-(Diethylamino)ethyl)-N-(2-methoxybenzyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C23H28N4O3S, CAS 403728-40-5
3-(2-(Diethylamino)ethyl)-N-(2-methoxybenzyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 403728-40-5C23H28N4O3S
N-Benzyl-N-(2-hydroxyethyl)-4-oxo-3-propyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C21H23N3O3S, CAS 403728-02-9
N-Benzyl-N-(2-hydroxyethyl)-4-oxo-3-propyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 403728-02-9C21H23N3O3S
N-Benzyl-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C21H23N3O2S, CAS 309940-27-0
N-Benzyl-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 309940-27-0C21H23N3O2S
N-Benzyl-N-methyl-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C22H25N3O2S, CAS 309940-28-1
N-Benzyl-N-methyl-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 309940-28-1C22H25N3O2S
N-[(2-Chlorophenyl)methyl]-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C21H22ClN3O2S, CAS 309940-35-0
N-[(2-Chlorophenyl)methyl]-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 309940-35-0C21H22ClN3O2S
N-[(4-Methoxyphenyl)methyl]-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C22H25N3O3S, CAS 421590-56-9
N-[(4-Methoxyphenyl)methyl]-4-oxo-3-pentyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 421590-56-9C22H25N3O3S
N-Benzyl-4-oxo-3-propyl-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C19H19N3O2S, CAS 403727-80-0
N-Benzyl-4-oxo-3-propyl-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 403727-80-0C19H19N3O2S
3-(2-Methoxyethyl)-N-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C20H21N3O4S, CAS 451466-16-3
3-(2-Methoxyethyl)-N-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 451466-16-3C20H21N3O4S
N-(2-Methoxybenzyl)-3-(2-methoxyethyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H21N3O4S, CAS 451466-17-4
N-(2-Methoxybenzyl)-3-(2-methoxyethyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 451466-17-4C20H21N3O4S
N-[(2-Chlorophenyl)methyl]-3-(2-methoxyethyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C19H18ClN3O3S, CAS 451466-18-5
N-[(2-Chlorophenyl)methyl]-3-(2-methoxyethyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 451466-18-5C19H18ClN3O3S
N-Benzyl-N-(2-hydroxyethyl)-3-(2-methoxyethyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C21H23N3O4S, CAS 451466-29-8
N-Benzyl-N-(2-hydroxyethyl)-3-(2-methoxyethyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 451466-29-8C21H23N3O4S
3-(2-Methoxyethyl)-N-[(4-methylphenyl)methyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide chemical structure, C20H21N3O3S, CAS 451466-08-3
3-(2-Methoxyethyl)-N-[(4-methylphenyl)methyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide
CAS 451466-08-3C20H21N3O3S
N-(4-Fluorobenzyl)-4-oxo-3-pentyl-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C21H22FN3O2S, CAS 421590-53-6
N-(4-Fluorobenzyl)-4-oxo-3-pentyl-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 421590-53-6C21H22FN3O2S