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Murcko scaffold

Ring system with 2 rings and 13 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
6
With full pages
4
Scaffold SMILES

O=C(Nc1nncs1)C1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nncs1)C1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)cyclopentanecarboxamide chemical structure, C10H15N3OS, CAS 352691-78-2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)cyclopentanecarboxamide
CAS 352691-78-2C10H15N3OS
N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)cyclopentanecarboxamide chemical structure, C10H15N3OS2, CAS 353774-20-6
N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)cyclopentanecarboxamide
CAS 353774-20-6C10H15N3OS2
N-[5-(2-Methylpropyl)-1,3,4-thiadiazol-2-yl]cyclopentanecarboxamide chemical structure, C12H19N3OS, CAS 879318-44-2
N-[5-(2-Methylpropyl)-1,3,4-thiadiazol-2-yl]cyclopentanecarboxamide
CAS 879318-44-2C12H19N3OS
(R)-2-((1-((5-Ethyl-1,3,4-thiadiazol-2-yl) carbamoyl)cyclopentyl)methyl)valeric acid chemical structure, C16H25N3O3S, CAS 337962-93-3
(R)-2-((1-((5-Ethyl-1,3,4-thiadiazol-2-yl) carbamoyl)cyclopentyl)methyl)valeric acid
CAS 337962-93-3C16H25N3O3S
UK-414495 chemical structure, C16H25N3O3S, CAS 388630-36-2
UK-414495
CAS 388630-36-2C16H25N3O3S
N-Butyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)cyclopentanecarboxamide chemical structure, C13H21N3OS, CAS 62347-22-2
N-Butyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)cyclopentanecarboxamide
CAS 62347-22-2C13H21N3OS