Murcko scaffold
1-(Pyrrolidin-3-yl)piperazine scaffold
75 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 75
- With full pages
- 7
Scaffold SMILES
C1CN(C2CCNC2)CCN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 75 chemicals
![tert-Butyl 4-[(3S)-pyrrolidin-3-yl]piperazine-1-carboxylate chemical structure, C13H25N3O2, CAS 1932790-66-3](/s/IZAYUAGLMWGXRH-NSHDSACASA-N.svg)
tert-Butyl 4-[(3S)-pyrrolidin-3-yl]piperazine-1-carboxylate
CAS 1932790-66-3C13H25N3O2
![tert-Butyl 4-[(3R)-pyrrolidin-3-yl]piperazine-1-carboxylate chemical structure, C13H25N3O2, CAS 1821785-94-7](/s/IZAYUAGLMWGXRH-LLVKDONJSA-N.svg)
tert-Butyl 4-[(3R)-pyrrolidin-3-yl]piperazine-1-carboxylate
CAS 1821785-94-7C13H25N3O2
1-Methyl-4-(pyrrolidin-3-yl)piperazine
CAS 202991-92-2C9H19N3
(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine dihydrochloride
CAS 116143-15-8C9H21Cl2N3
(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine
CAS 771438-38-1C9H19N3
(S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine
CAS 1067716-49-7C9H19N3
(3S,4S)-4-(4-Methylpiperazin-1-yl)pyrrolidin-3-ol
C9H19N3O
![1-[(3R)-Pyrrolidin-3-yl]piperazine chemical structure, C8H17N3, CAS 2869872-46-6](/s/USVCMXLIEXLLBB-MRVPVSSYSA-N.svg)
1-[(3R)-Pyrrolidin-3-yl]piperazine
CAS 2869872-46-6C8H17N3
![1-[(3S)-Pyrrolidin-3-yl]piperazine chemical structure, C8H17N3, CAS 2869872-06-8](/s/USVCMXLIEXLLBB-QMMMGPOBSA-N.svg)
1-[(3S)-Pyrrolidin-3-yl]piperazine
CAS 2869872-06-8C8H17N3
(R)-1-Ethyl-4-(pyrrolidin-3-yl)piperazine
CAS 1932243-65-6C10H21N3
(S)-1-Ethyl-4-(pyrrolidin-3-yl)piperazine
CAS 1932414-95-3C10H21N3
1-Piperazineethanol, 4-(3S)-3-pyrrolidinyl-
CAS 1067716-50-0C10H21N3O
tert-Butyl 4-(pyrrolidin-3-yl)piperazine-1-carboxylate
CAS 885959-36-4C13H25N3O2
1-(Pyrrolidin-3-yl)piperazine
CAS 939793-68-7C8H17N3
1-Ethyl-4-(pyrrolidin-3-yl)piperazine
CAS 1181375-80-3C10H21N3
tert-Butyl 3-(piperazin-1-yl)pyrrolidine-1-carboxylate
CAS 867265-71-2C13H25N3O2
![Ethyl 4-[1-(tert-butoxycarbonyl)pyrrolidin-3-yl]piperazine-1-carboxylate chemical structure, C16H29N3O4, CAS 1291486-42-4](/s/OMIUGTADIICGOH-UHFFFAOYSA-N.svg)
Ethyl 4-[1-(tert-butoxycarbonyl)pyrrolidin-3-yl]piperazine-1-carboxylate
CAS 1291486-42-4C16H29N3O4
trans-4-(4-Methyl-1-piperazinyl)-3-pyrrolidinol
CAS 897652-69-6C9H19N3O
(S)-tert-Butyl 3-(piperazin-1-yl)pyrrolidine-1-carboxylate
CAS 1010446-31-7C13H25N3O2
(R)-tert-Butyl 3-(piperazin-1-yl)pyrrolidine-1-carboxylate
CAS 717927-58-7C13H25N3O2
tert-Butyl 3-(1-piperazinyl)-1-pyrrolidinecarboxylate dihydrochloride
CAS 1332530-47-8C13H27Cl2N3O2
1-Methyl-4-(3-pyrrolidinyl)piperazine dihydrochloride
CAS 1219980-00-3C9H21Cl2N3
![2-[4-(3-Pyrrolidinyl)-1-piperazinyl]-1-ethanol dihydrochloride chemical structure, C10H23Cl2N3O, CAS 1220020-39-2](/s/VYFWUDLACQFOIT-UHFFFAOYSA-N.svg)
2-[4-(3-Pyrrolidinyl)-1-piperazinyl]-1-ethanol dihydrochloride
CAS 1220020-39-2C10H23Cl2N3O
tert-Butyl 3-(4-methylpiperazin-1-yl)pyrrolidine-1-carboxylate
CAS 1097922-17-2C14H27N3O2
- 1-(1-Methylpyrrolidin-3-yl)piperazine1491899-68-3C9H19N3
- 1-(4-(Pyrrolidin-3-yl)piperazin-1-yl)ethan-1-one666853-72-1C10H19N3O
- 3-Methyl-1-(1-methylpyrrolidin-3-yl)piperazine1478062-11-1C10H21N3
- 1-Propyl-4-(3S)-3-pyrrolidinylpiperazine1010446-32-8C11H23N3
- tert-Butyl (3S)-3-(4-propylpiperazin-1-yl)pyrrolidine-1-carboxylate1010446-30-6C16H31N3O2
- (S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine dihydrobromide1067658-51-8C9H21Br2N3
- 1-(3-(Piperazin-1-yl)pyrrolidin-1-yl)ethanone1780405-59-5C10H19N3O
- trans-4-(4-Methyl-1-piperazinyl)-3-pyrrolidinol trihydrochloride1262769-85-6C9H22Cl3N3O
- 1-[4-(4-Methylpyrrolidin-3-yl)piperazin-1-yl]ethan-1-one1384430-83-4C11H21N3O
- 2-[3-(4-Acetylpiperazin-1-yl)-4-methylpyrrolidin-1-yl]-N-(cyanomethyl)acetamide1384719-55-4C15H25N5O2
- 1-Methyl-4-(3-pyrrolidinyl)piperazine trihydrochloride1390654-38-2C9H22Cl3N3
- 1-(Propan-2-yl)-4-(pyrrolidin-3-yl)piperazine1250728-21-2C11H23N3
- tert-Butyl 3-hydroxy-4-(piperazin-1-yl)pyrrolidine-1-carboxylate1368133-47-4C13H25N3O3
- (3R,4R)-4-(4-Methylpiperazin-1-yl)pyrrolidin-3-ol1422498-02-9C9H19N3O
- (S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride2512230-61-2C9H22Cl3N3
- (R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride917505-14-7C9H22Cl3N3
- (R)-1-(4-(Pyrrolidin-3-yl)piperazin-1-yl)ethan-1-one3058892-45-5C10H19N3O
- (S)-1-(4-(Pyrrolidin-3-yl)piperazin-1-yl)ethan-1-one2382550-56-1C10H19N3O
- (R)-1-Isopropyl-4-(pyrrolidin-3-yl)piperazine3058892-47-7C11H23N3
- (S)-1-Isopropyl-4-(pyrrolidin-3-yl)piperazine2322619-35-0C11H23N3
- tert-Butyl (3R,4R)-3-hydroxy-4-(piperazin-1-yl)pyrrolidine-1-carboxylate2361923-20-6C13H25N3O3
- rac-tert-Butyl (3R,4R)-3-hydroxy-4-(piperazin-1-yl)pyrrolidine-1-carboxylate2202367-29-9C13H25N3O3
- (S)-1-(4,4-Difluoropyrrolidin-3-yl)-4-methylpiperazine1897771-80-0C9H17F2N3
- 1-(4,4-Difluoropyrrolidin-3-yl)-4-methylpiperazine1897714-67-8C9H17F2N3
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