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Murcko scaffold

2-(1H-Pyrazol-3-yl)-1,3-thiazole scaffold

69 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 10
Chemicals: 69
With full pages: 8

Scaffold SMILES

c1csc(-c2cc[nH]n2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(1H-Pyrazol-3-yl)-1,3-thiazole page

Murcko scaffold c1csc(-c2cc[nH]n2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

2-(1-Methyl-1H-pyrazol-3-yl)-1,3-thiazole chemical structure, C7H7N3S, CAS 648408-55-3

2-(1-Methyl-1H-pyrazol-3-yl)-1,3-thiazole

CAS 648408-55-3C₇H₇N₃S

2-(1H-Pyrazol-3-yl)-1,3-thiazole chemical structure, C6H5N3S, CAS 166196-73-2

2-(1H-Pyrazol-3-yl)-1,3-thiazole

CAS 166196-73-2C₆H₅N₃S

2-(5-Methyl-1H-pyrazol-3-yl)-1,3-thiazole chemical structure, C7H7N3S, CAS 1187559-72-3

2-(5-Methyl-1H-pyrazol-3-yl)-1,3-thiazole

CAS 1187559-72-3C₇H₇N₃S

Ethyl 5-(1,3-thiazol-2-yl)-1H-pyrazole-3-carboxylate chemical structure, C9H9N3O2S, CAS 174139-53-8

Ethyl 5-(1,3-thiazol-2-yl)-1H-pyrazole-3-carboxylate

CAS 174139-53-8C₉H₉N₃O₂S

2-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)thiazole chemical structure, C8H6F3N3S, CAS 223499-08-9

2-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)thiazole

CAS 223499-08-9C₈H₆F₃N₃S

5-(2-Thiazolyl)-3-(trifluoromethyl)-1H-pyrazole chemical structure, C7H4F3N3S, CAS 188920-85-6

5-(2-Thiazolyl)-3-(trifluoromethyl)-1H-pyrazole

CAS 188920-85-6C₇H₄F₃N₃S

2-(1-(tert-Butyl)-1H-pyrazol-5-yl)thiazole chemical structure, C10H13N3S, CAS 1269291-71-5

2-(1-(tert-Butyl)-1H-pyrazol-5-yl)thiazole

CAS 1269291-71-5C₁₀H₁₃N₃S

2-(1-Methyl-1H-pyrazol-5-yl)thiazole chemical structure, C7H7N3S, CAS 1269292-62-7

2-(1-Methyl-1H-pyrazol-5-yl)thiazole

CAS 1269292-62-7C₇H₇N₃S

2-(1-Methyl-1H-pyrazol-5-yl)-1,3-thiazole-5-carboxylic acid chemical structure, C8H7N3O2S, CAS 1202632-40-3

2-(1-Methyl-1H-pyrazol-5-yl)-1,3-thiazole-5-carboxylic acid

CAS 1202632-40-3C₈H₇N₃O₂S

Ethyl 2-(1-methyl-1H-pyrazol-5-yl)thiazole-5-carboxylate chemical structure, C10H11N3O2S, CAS 1202632-39-0

Ethyl 2-(1-methyl-1H-pyrazol-5-yl)thiazole-5-carboxylate

CAS 1202632-39-0C₁₀H₁₁N₃O₂S

2-(4-Chloro-1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-5-carboxylic acid chemical structure, C8H6ClN3O2S, CAS 1202632-43-6

2-(4-Chloro-1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-5-carboxylic acid

CAS 1202632-43-6C₈H₆ClN₃O₂S

Ethyl 2-(4-chloro-1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-4-carboxylate chemical structure, C10H10ClN3O2S, CAS 1202248-00-7

Ethyl 2-(4-chloro-1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-4-carboxylate

CAS 1202248-00-7C₁₀H₁₀ClN₃O₂S

2-(1-Methyl-1H-pyrazol-5-yl)-4-thiazolecarboxylic acid chemical structure, C8H7N3O2S, CAS 1202247-97-9

2-(1-Methyl-1H-pyrazol-5-yl)-4-thiazolecarboxylic acid

CAS 1202247-97-9C₈H₇N₃O₂S

2-(4-Chloro-1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C8H6ClN3O2S, CAS 1202248-01-8

2-(4-Chloro-1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-4-carboxylic acid

CAS 1202248-01-8C₈H₆ClN₃O₂S

Ethyl 2-(1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-4-carboxylate chemical structure, C10H11N3O2S, CAS 1202247-96-8

Ethyl 2-(1-methyl-1H-pyrazol-5-yl)-1,3-thiazole-4-carboxylate

CAS 1202247-96-8C₁₀H₁₁N₃O₂S

5-(Thiazol-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-ylboronic acid chemical structure, C12H20BN3O3SSi, CAS 1313518-21-6

5-(Thiazol-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-4-ylboronic acid

CAS 1313518-21-6C₁₂H₂₀BN₃O₃SSi

B-[1-methyl-3-(2-thiazolyl)-1H-pyrazol-5-yl]boronic acid chemical structure, C7H8BN3O2S, CAS 1345118-93-5

B-[1-methyl-3-(2-thiazolyl)-1H-pyrazol-5-yl]boronic acid

CAS 1345118-93-5C₇H₈BN₃O₂S

4-Methyl-2-(2H-pyrazol-3-yl)-thiazole-5-carboxylic acid ethyl ester chemical structure, C10H11N3O2S, CAS 1009378-41-9

4-Methyl-2-(2H-pyrazol-3-yl)-thiazole-5-carboxylic acid ethyl ester

CAS 1009378-41-9C₁₀H₁₁N₃O₂S

3-(1,3-Thiazol-2-yl)-1H-pyrazol-4-amine chemical structure, C6H6N4S, CAS 1492419-64-3

3-(1,3-Thiazol-2-yl)-1H-pyrazol-4-amine

CAS 1492419-64-3C₆H₆N₄S

1-Methyl-3-(1,3-thiazol-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C8H7N3O2S, CAS 1464016-14-5

1-Methyl-3-(1,3-thiazol-2-yl)-1H-pyrazole-4-carboxylic acid

CAS 1464016-14-5C₈H₇N₃O₂S

2-(4-Bromo-1H-pyrazol-3-yl)-1,3-thiazole chemical structure, C6H4BrN3S, CAS 166196-37-8

2-(4-Bromo-1H-pyrazol-3-yl)-1,3-thiazole

CAS 166196-37-8C₆H₄BrN₃S

2-(4-Nitro-1H-pyrazol-3-yl)-1,3-thiazole chemical structure, C6H4N4O2S, CAS 1496150-24-3

2-(4-Nitro-1H-pyrazol-3-yl)-1,3-thiazole

CAS 1496150-24-3C₆H₄N₄O₂S

3-(1,3-Thiazol-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C7H5N3O2S, CAS 1489142-70-2

3-(1,3-Thiazol-2-yl)-1H-pyrazole-4-carboxylic acid

CAS 1489142-70-2C₇H₅N₃O₂S

4-(Chloromethyl)-2-(1-methyl-1H-pyrazol-3-yl)-1,3-thiazole chemical structure, C8H8ClN3S, CAS 1491508-77-0

4-(Chloromethyl)-2-(1-methyl-1H-pyrazol-3-yl)-1,3-thiazole

CAS 1491508-77-0C₈H₈ClN₃S