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Murcko scaffold

Ring system with 3 rings and 17 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
20
With full pages
3
Scaffold SMILES

O=C(c1cc2ccccc2s1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cc2ccccc2s1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

3-Chloro-6-methylbenzo[b]thiophen-2-yl piperidyl ketone chemical structure, C15H16ClNOS, CAS 312938-77-5
3-Chloro-6-methylbenzo[b]thiophen-2-yl piperidyl ketone
CAS 312938-77-5C15H16ClNOS
1-[(3,6-Dichloro-1-benzothien-2-yl)carbonyl]piperidine chemical structure, C14H13Cl2NOS, CAS 314046-02-1
1-[(3,6-Dichloro-1-benzothien-2-yl)carbonyl]piperidine
CAS 314046-02-1C14H13Cl2NOS
(3-Chloro-1-benzothiophen-2-yl)(piperidin-1-yl)methanone chemical structure, C14H14ClNOS, CAS 63674-41-9
(3-Chloro-1-benzothiophen-2-yl)(piperidin-1-yl)methanone
CAS 63674-41-9C14H14ClNOS
1-[(3,6-Dichloro-1-benzothien-2-yl)carbonyl]-4-methylpiperidine chemical structure, C15H15Cl2NOS, CAS 314046-03-2
1-[(3,6-Dichloro-1-benzothien-2-yl)carbonyl]-4-methylpiperidine
CAS 314046-03-2C15H15Cl2NOS
1-[(3-Chloro-1-benzothien-2-yl)carbonyl]-4-methylpiperidine chemical structure, C15H16ClNOS, CAS 331001-53-7
1-[(3-Chloro-1-benzothien-2-yl)carbonyl]-4-methylpiperidine
CAS 331001-53-7C15H16ClNOS
Ethyl 1-(3-chloro-1-benzothiophene-2-carbonyl)piperidine-4-carboxylate chemical structure, C17H18ClNO3S, CAS 521322-56-5
Ethyl 1-(3-chloro-1-benzothiophene-2-carbonyl)piperidine-4-carboxylate
CAS 521322-56-5C17H18ClNO3S
1-({3-Chloro-6-nitro-1-benzothien-2-yl}carbonyl)-3-methylpiperidine chemical structure, C15H15ClN2O3S, CAS 351981-95-8
1-({3-Chloro-6-nitro-1-benzothien-2-yl}carbonyl)-3-methylpiperidine
CAS 351981-95-8C15H15ClN2O3S
Methyl 1-(3-chloro-1-benzothiophene-2-carbonyl)piperidine-4-carboxylate chemical structure, C16H16ClNO3S, CAS 600122-25-6
Methyl 1-(3-chloro-1-benzothiophene-2-carbonyl)piperidine-4-carboxylate
CAS 600122-25-6C16H16ClNO3S
Piperidine, 1-[(5-nitrobenzo[b]thien-2-yl)carbonyl]- chemical structure, C14H14N2O3S, CAS 97528-67-1
Piperidine, 1-[(5-nitrobenzo[b]thien-2-yl)carbonyl]-
CAS 97528-67-1C14H14N2O3S
(3-Chloro-1-benzothiophen-2-yl)-(2,6-dimethylpiperidin-1-yl)methanone chemical structure, C16H18ClNOS, CAS 544433-48-9
(3-Chloro-1-benzothiophen-2-yl)-(2,6-dimethylpiperidin-1-yl)methanone
CAS 544433-48-9C16H18ClNOS
(3-Chloro-1-benzothiophen-2-yl)-(3-methylpiperidin-1-yl)methanone chemical structure, C15H16ClNOS, CAS 328280-39-3
(3-Chloro-1-benzothiophen-2-yl)-(3-methylpiperidin-1-yl)methanone
CAS 328280-39-3C15H16ClNOS
(3,6-Dichloro-1-benzothiophen-2-yl)(2,6-dimethylpiperidin-1-yl)methanone chemical structure, C16H17Cl2NOS, CAS 444906-48-3
(3,6-Dichloro-1-benzothiophen-2-yl)(2,6-dimethylpiperidin-1-yl)methanone
CAS 444906-48-3C16H17Cl2NOS
(3,5-Dimethylpiperidin-1-yl)(5-nitrobenzo[b]thiophen-2-yl)methanone chemical structure, C16H18N2O3S, CAS 361167-84-2
(3,5-Dimethylpiperidin-1-yl)(5-nitrobenzo[b]thiophen-2-yl)methanone
CAS 361167-84-2C16H18N2O3S
(3-Chloro-6-methyl-1-benzothiophen-2-yl)(4-methylpiperidino)methanone chemical structure, C16H18ClNOS, CAS 544656-71-5
(3-Chloro-6-methyl-1-benzothiophen-2-yl)(4-methylpiperidino)methanone
CAS 544656-71-5C16H18ClNOS
Piperidine, 1-[(5-aminobenzo[b]thien-2-yl)carbonyl]- chemical structure, C14H16N2OS, CAS 832102-94-0
Piperidine, 1-[(5-aminobenzo[b]thien-2-yl)carbonyl]-
CAS 832102-94-0C14H16N2OS
2-((1-(5-Fluorobenzo[b]thiophene-2-carbonyl)piperidin-4-yl)sulfonyl)-N-methylacetamide chemical structure, C17H19FN2O4S2, CAS 1798033-92-7
2-((1-(5-Fluorobenzo[b]thiophene-2-carbonyl)piperidin-4-yl)sulfonyl)-N-methylacetamide
CAS 1798033-92-7C17H19FN2O4S2
Methyl 2-((1-(5-fluorobenzo[b]thiophene-2-carbonyl)piperidin-4-yl)sulfonyl)acetate chemical structure, C17H18FNO5S2, CAS 1448030-77-0
Methyl 2-((1-(5-fluorobenzo[b]thiophene-2-carbonyl)piperidin-4-yl)sulfonyl)acetate
CAS 1448030-77-0C17H18FNO5S2
(5-Fluorobenzo[b]thiophen-2-yl)(4-(isobutylsulfonyl)piperidin-1-yl)methanone chemical structure, C18H22FNO3S2, CAS 1797630-16-0
(5-Fluorobenzo[b]thiophen-2-yl)(4-(isobutylsulfonyl)piperidin-1-yl)methanone
CAS 1797630-16-0C18H22FNO3S2
4-Azido-1-(1-benzothiophene-2-carbonyl)piperidine chemical structure, C14H14N4OS, CAS 3054582-07-6
4-Azido-1-(1-benzothiophene-2-carbonyl)piperidine
CAS 3054582-07-6C14H14N4OS
1-(1-Benzothiophene-2-carbonyl)-4-(fluoromethyl)piperidine chemical structure, C15H16FNOS, CAS 2741901-68-6
1-(1-Benzothiophene-2-carbonyl)-4-(fluoromethyl)piperidine
CAS 2741901-68-6C15H16FNOS