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Murcko scaffold

2-Benzylisoindolin-1-one scaffold

156 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
156
With full pages
24
Scaffold SMILES

O=C1c2ccccc2CN1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzylisoindolin-1-one page
Murcko scaffold O=C1c2ccccc2CN1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 156 chemicals

1H-Isoindol-1-one, 2-((3,4-dichlorophenyl)methyl)-2,3-dihydro- chemical structure, C15H11Cl2NO, CAS 62041-80-9
1H-Isoindol-1-one, 2-((3,4-dichlorophenyl)methyl)-2,3-dihydro-
CAS 62041-80-9C15H11Cl2NO
2-Benzyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid chemical structure, C16H13NO3, CAS 77960-29-3
2-Benzyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid
CAS 77960-29-3C16H13NO3
2-(3-Methoxy-benzyl)-2,3-dihydro-isoindol-1-one chemical structure, C16H15NO2, CAS 667897-37-2
2-(3-Methoxy-benzyl)-2,3-dihydro-isoindol-1-one
CAS 667897-37-2C16H15NO2
2-((3,4-Dimethoxyphenyl)methyl)-2,3-dihydro-3-oxo-1H-isoindole-4-carboxylic acid chemical structure, C18H17NO5, CAS 728024-39-3
2-((3,4-Dimethoxyphenyl)methyl)-2,3-dihydro-3-oxo-1H-isoindole-4-carboxylic acid
CAS 728024-39-3C18H17NO5
2-Benzylisoindolin-1-one chemical structure, C15H13NO, CAS 13380-32-0
2-Benzylisoindolin-1-one
CAS 13380-32-0C15H13NO
4-((1-Oxoisoindolin-2-yl)methyl)benzoic acid chemical structure, C16H13NO3, CAS 503039-50-7
4-((1-Oxoisoindolin-2-yl)methyl)benzoic acid
CAS 503039-50-7C16H13NO3
3-(4-Ethoxy-3-methoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C20H21NO5, CAS 885951-50-8
3-(4-Ethoxy-3-methoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 885951-50-8C20H21NO5
3-(2,3-Dichlorophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C17H13Cl2NO3, CAS 885949-95-1
3-(2,3-Dichlorophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 885949-95-1C17H13Cl2NO3
3-(4-Methylphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C18H17NO3, CAS 439095-70-2
3-(4-Methylphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 439095-70-2C18H17NO3
3-(4-Methoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C18H17NO4, CAS 167886-73-9
3-(4-Methoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 167886-73-9C18H17NO4
1,3-Dihydro-beta-(3-hydroxyphenyl)-1-oxo-2H-isoindole-2-propanoic acid chemical structure, C17H15NO4, CAS 477848-97-8
1,3-Dihydro-beta-(3-hydroxyphenyl)-1-oxo-2H-isoindole-2-propanoic acid
CAS 477848-97-8C17H15NO4
3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)-3-[4-(trifluoromethyl)phenyl]propanoic acid chemical structure, C18H14F3NO3, CAS 439096-93-2
3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)-3-[4-(trifluoromethyl)phenyl]propanoic acid
CAS 439096-93-2C18H14F3NO3
3-(4-Ethylphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C19H19NO3, CAS 439096-97-6
3-(4-Ethylphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 439096-97-6C19H19NO3
(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)(phenyl)acetic acid chemical structure, C16H13NO3, CAS 101004-95-9
(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)(phenyl)acetic acid
CAS 101004-95-9C16H13NO3
3-(2,4-Difluorophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C17H13F2NO3, CAS 860784-48-1
3-(2,4-Difluorophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 860784-48-1C17H13F2NO3
2-[(2-Benzyl-3-oxo-2,3-dihydro-1H-isoindol-1-yl)sulfanyl]acetic acid chemical structure, C17H15NO3S, CAS 97132-10-0
2-[(2-Benzyl-3-oxo-2,3-dihydro-1H-isoindol-1-yl)sulfanyl]acetic acid
CAS 97132-10-0C17H15NO3S
2-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2-(phenyl)-acetamide chemical structure, C16H14N2O2, CAS 30762-83-5
2-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2-(phenyl)-acetamide
CAS 30762-83-5C16H14N2O2
2-Benzyl-3-hydroxy-2,3-dihydro-1H-isoindol-1-one chemical structure, C15H13NO2, CAS 17448-14-5
2-Benzyl-3-hydroxy-2,3-dihydro-1H-isoindol-1-one
CAS 17448-14-5C15H13NO2
3-(4-Bromophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C17H14BrNO3, CAS 478079-08-2
3-(4-Bromophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 478079-08-2C17H14BrNO3
3-(2-Fluorophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C17H14FNO3, CAS 383148-31-0
3-(2-Fluorophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 383148-31-0C17H14FNO3
3-(3,4-Dimethoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C19H19NO5, CAS 167886-75-1
3-(3,4-Dimethoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 167886-75-1C19H19NO5
3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)-3-[3-(trifluoromethyl)phenyl]propanoic acid chemical structure, C18H14F3NO3, CAS 478260-15-0
3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)-3-[3-(trifluoromethyl)phenyl]propanoic acid
CAS 478260-15-0C18H14F3NO3
3-(4-Ethoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C19H19NO4, CAS 478260-16-1
3-(4-Ethoxyphenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 478260-16-1C19H19NO4
3-(2-Bromophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C17H14BrNO3, CAS 478260-17-2
3-(2-Bromophenyl)-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 478260-17-2C17H14BrNO3