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Murcko scaffold

2-Benzylidene-1,3-indandione scaffold

76 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
76
With full pages
14
Scaffold SMILES

O=C1C(=Cc2ccccc2)C(=O)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzylidene-1,3-indandione page
Murcko scaffold O=C1C(=Cc2ccccc2)C(=O)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 76 chemicals

2-((4-(Dimethylamino)phenyl)methylene)-1H-indene-1,3(2H)-dione chemical structure, C18H15NO2, CAS 21889-13-4
2-((4-(Dimethylamino)phenyl)methylene)-1H-indene-1,3(2H)-dione
CAS 21889-13-4C18H15NO2
1H-Indene-1,3(2H)-dione, 2-((4-(diethylamino)phenyl)methylene)- chemical structure, C20H19NO2, CAS 34200-53-8
1H-Indene-1,3(2H)-dione, 2-((4-(diethylamino)phenyl)methylene)-
CAS 34200-53-8C20H19NO2
2-Benzylidene-1,3-indandione chemical structure, C16H10O2, CAS 5381-33-9
2-Benzylidene-1,3-indandione
CAS 5381-33-9C16H10O2
2-[(4-Nitrophenyl)methylidene]indene-1,3-dione chemical structure, C16H9NO4, CAS 15875-60-2
2-[(4-Nitrophenyl)methylidene]indene-1,3-dione
CAS 15875-60-2C16H9NO4
2-[(3,5-Ditert-butyl-4-hydroxyphenyl)methylidene]indene-1,3-dione chemical structure, C24H26O3, CAS 53566-09-9
2-[(3,5-Ditert-butyl-4-hydroxyphenyl)methylidene]indene-1,3-dione
CAS 53566-09-9C24H26O3
2-(4-Hydroxybenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C16H10O3, CAS 25329-41-3
2-(4-Hydroxybenzylidene)-1H-indene-1,3(2H)-dione
CAS 25329-41-3C16H10O3
2-[(4-Hydroxy-3,5-dimethylphenyl)methylidene]-1H-indene-1,3(2H)-dione chemical structure, C18H14O3, CAS 53566-05-5
2-[(4-Hydroxy-3,5-dimethylphenyl)methylidene]-1H-indene-1,3(2H)-dione
CAS 53566-05-5C18H14O3
2-{[4-Hydroxy-3,5-di(propan-2-yl)phenyl]methylidene}-1H-indene-1,3(2H)-dione chemical structure, C22H22O3, CAS 53608-00-7
2-{[4-Hydroxy-3,5-di(propan-2-yl)phenyl]methylidene}-1H-indene-1,3(2H)-dione
CAS 53608-00-7C22H22O3
2-(3,5-Dichloro-4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C16H8Cl2O3, CAS 25315-19-9
2-(3,5-Dichloro-4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione
CAS 25315-19-9C16H8Cl2O3
3-Hydroxy-2-(phenylcarbonyl)-1H-inden-1-one chemical structure, C16H10O3, CAS 27832-50-4
3-Hydroxy-2-(phenylcarbonyl)-1H-inden-1-one
CAS 27832-50-4C16H10O3
2-(4-Methoxybenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C17H12O3, CAS 7421-76-3
2-(4-Methoxybenzylidene)-1H-indene-1,3(2H)-dione
CAS 7421-76-3C17H12O3
2-[(4-Chlorophenyl)methylene]-1H-indene-1,3(2H)-dione chemical structure, C16H9ClO2, CAS 15875-54-4
2-[(4-Chlorophenyl)methylene]-1H-indene-1,3(2H)-dione
CAS 15875-54-4C16H9ClO2
1H-Indene-1,3(2H)-dione, 2-[(4-fluorophenyl)methylene]- chemical structure, C16H9FO2, CAS 16210-64-3
1H-Indene-1,3(2H)-dione, 2-[(4-fluorophenyl)methylene]-
CAS 16210-64-3C16H9FO2
2-(3,4-Dihydroxybenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C16H10O4, CAS 78426-09-2
2-(3,4-Dihydroxybenzylidene)-1H-indene-1,3(2H)-dione
CAS 78426-09-2C16H10O4
2-(2-Nitrobenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C16H9NO4, CAS 15875-61-3
2-(2-Nitrobenzylidene)-1H-indene-1,3(2H)-dione
CAS 15875-61-3C16H9NO4
2-((4-Ethoxyphenyl)methylene)indane-1,3-dione chemical structure, C18H14O3, CAS 57189-82-9
2-((4-Ethoxyphenyl)methylene)indane-1,3-dione
CAS 57189-82-9C18H14O3
2-((3,4-Dimethoxyphenyl)methylidene)-1H-indene-1,3(2H)-dione chemical structure, C18H14O4, CAS 58161-74-3
2-((3,4-Dimethoxyphenyl)methylidene)-1H-indene-1,3(2H)-dione
CAS 58161-74-3C18H14O4
1H-Indene-1,3(2H)-dione, 2-[(4-methylphenyl)methylene]- chemical structure, C17H12O2, CAS 15875-51-1
1H-Indene-1,3(2H)-dione, 2-[(4-methylphenyl)methylene]-
CAS 15875-51-1C17H12O2
2-(4-Hydroxy-3-methoxybenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C17H12O4, CAS 58161-73-2
2-(4-Hydroxy-3-methoxybenzylidene)-1H-indene-1,3(2H)-dione
CAS 58161-73-2C17H12O4
1H-Indene-1,3(2H)-dione, 2-[(2-chlorophenyl)methylene]- chemical structure, C16H9ClO2, CAS 15875-56-6
1H-Indene-1,3(2H)-dione, 2-[(2-chlorophenyl)methylene]-
CAS 15875-56-6C16H9ClO2
2-[(2,5-Dimethoxyphenyl)methylidene]indene-1,3-dione chemical structure, C18H14O4, CAS 67200-96-8
2-[(2,5-Dimethoxyphenyl)methylidene]indene-1,3-dione
CAS 67200-96-8C18H14O4
2-[(3-Bromo-4-methoxyphenyl)methylene]-1H-indene-1,3(2H)-dione chemical structure, C17H11BrO3, CAS 25315-17-7
2-[(3-Bromo-4-methoxyphenyl)methylene]-1H-indene-1,3(2H)-dione
CAS 25315-17-7C17H11BrO3
2-(3-Nitrobenzylidene)-1H-indene-1,3(2H)-dione chemical structure, C16H9NO4, CAS 7421-77-4
2-(3-Nitrobenzylidene)-1H-indene-1,3(2H)-dione
CAS 7421-77-4C16H9NO4
2-[(2-Fluorophenyl)methylene]-1H-indene-1,3(2H)-dione chemical structure, C16H9FO2, CAS 19371-91-6
2-[(2-Fluorophenyl)methylene]-1H-indene-1,3(2H)-dione
CAS 19371-91-6C16H9FO2