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Murcko scaffold

Benzylphthalimide scaffold

252 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
252
With full pages
37
Scaffold SMILES

O=C1c2ccccc2C(=O)N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Benzylphthalimide page
Murcko scaffold O=C1c2ccccc2C(=O)N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 252 chemicals

Benzylphthalimide chemical structure, C15H11NO2, CAS 2142-01-0
Benzylphthalimide
CAS 2142-01-0C15H11NO2
2-[(5-Amino-2-methylphenyl)methyl]-1H-isoindole-1,3(2H)-dione chemical structure, C16H14N2O2, CAS 6284-54-4
2-[(5-Amino-2-methylphenyl)methyl]-1H-isoindole-1,3(2H)-dione
CAS 6284-54-4C16H14N2O2
2-Benzyl-4-nitro-isoindole-1,3-dione chemical structure, C15H10N2O4, CAS 92438-39-6
2-Benzyl-4-nitro-isoindole-1,3-dione
CAS 92438-39-6C15H10N2O4
Methyl 3-(1,3-dioxoisoindol-2-yl)-3-(3-nitrophenyl)propanoate chemical structure, C18H14N2O6, CAS 6329-27-7
Methyl 3-(1,3-dioxoisoindol-2-yl)-3-(3-nitrophenyl)propanoate
CAS 6329-27-7C18H14N2O6
Methyl 3-(3-aminophenyl)-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate chemical structure, C18H16N2O4, CAS 6329-29-9
Methyl 3-(3-aminophenyl)-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
CAS 6329-29-9C18H16N2O4
Methyl 3-{3-[bis(2-hydroxyethyl)amino]phenyl}-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate chemical structure, C22H24N2O6, CAS 6327-94-2
Methyl 3-{3-[bis(2-hydroxyethyl)amino]phenyl}-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
CAS 6327-94-2C22H24N2O6
Ethyl 2-(1,3-dioxoisoindolin-2-yl)-2-phenylacetate chemical structure, C18H15NO4, CAS 6635-55-8
Ethyl 2-(1,3-dioxoisoindolin-2-yl)-2-phenylacetate
CAS 6635-55-8C18H15NO4
1H-Isoindole-1,3(2H)-dione, 2-[(4-chlorophenyl)methyl]- chemical structure, C15H10ClNO2, CAS 131523-32-5
1H-Isoindole-1,3(2H)-dione, 2-[(4-chlorophenyl)methyl]-
CAS 131523-32-5C15H10ClNO2
Isoindole-1,3-dione, 2-(2,4,6-trimethylbenzyl)- chemical structure, C18H17NO2, CAS 64489-90-3
Isoindole-1,3-dione, 2-(2,4,6-trimethylbenzyl)-
CAS 64489-90-3C18H17NO2
2-((1,3-Dioxoisoindolin-2-yl)methyl)benzaldehyde chemical structure, C16H11NO3, CAS 408527-91-3
2-((1,3-Dioxoisoindolin-2-yl)methyl)benzaldehyde
CAS 408527-91-3C16H11NO3
2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoyl chloride chemical structure, C16H10ClNO3, CAS 345927-99-3
2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzoyl chloride
CAS 345927-99-3C16H10ClNO3
2-(4-Nitrobenzyl)isoindole-1,3-dione chemical structure, C15H10N2O4, CAS 62133-07-7
2-(4-Nitrobenzyl)isoindole-1,3-dione
CAS 62133-07-7C15H10N2O4
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)(phenyl)acetic acid chemical structure, C16H11NO4, CAS 4695-37-8
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)(phenyl)acetic acid
CAS 4695-37-8C16H11NO4
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)(phenyl)acetyl chloride chemical structure, C16H10ClNO3, CAS 5688-96-0
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)(phenyl)acetyl chloride
CAS 5688-96-0C16H10ClNO3
N-(3-Bromomethylbenzyl)phthalimide chemical structure, C16H12BrNO2, CAS 101207-74-3
N-(3-Bromomethylbenzyl)phthalimide
CAS 101207-74-3C16H12BrNO2
MS-1845 chemical structure, C15H10N2O4, CAS 21081-63-0
MS-1845
CAS 21081-63-0C15H10N2O4
2-[(2-Nitrophenyl)methyl]isoindole-1,3-dione chemical structure, C15H10N2O4, CAS 35970-03-7
2-[(2-Nitrophenyl)methyl]isoindole-1,3-dione
CAS 35970-03-7C15H10N2O4
4-[(1,3-Dioxoisoindol-2-yl)methyl]benzenesulfonamide chemical structure, C15H12N2O4S, CAS 7518-98-1
4-[(1,3-Dioxoisoindol-2-yl)methyl]benzenesulfonamide
CAS 7518-98-1C15H12N2O4S
2-[(4-Chloro-2-nitrophenyl)methyl]isoindole-1,3-dione chemical structure, C15H9ClN2O4, CAS 81729-52-4
2-[(4-Chloro-2-nitrophenyl)methyl]isoindole-1,3-dione
CAS 81729-52-4C15H9ClN2O4
2-(2-Bromobenzyl)isoindoline-1,3-dione chemical structure, C15H10BrNO2, CAS 183735-79-7
2-(2-Bromobenzyl)isoindoline-1,3-dione
CAS 183735-79-7C15H10BrNO2
CC-1069 chemical structure, C19H18N2O5, CAS 167887-03-8
CC-1069
CAS 167887-03-8C19H18N2O5
1,3-Dihydro-1,3-dioxo-beta-phenyl-2H-isoindole-2-propanamide chemical structure, C17H14N2O3, CAS 467421-06-3
1,3-Dihydro-1,3-dioxo-beta-phenyl-2H-isoindole-2-propanamide
CAS 467421-06-3C17H14N2O3
(R)-2-(1-Phenylethyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3-dione chemical structure, C16H9F4NO2, CAS 182690-77-3
(R)-2-(1-Phenylethyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3-dione
CAS 182690-77-3C16H9F4NO2
N-(4-Methoxybenzyl)phthalimide chemical structure, C16H13NO3, CAS 21244-24-6
N-(4-Methoxybenzyl)phthalimide
CAS 21244-24-6C16H13NO3