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Murcko scaffold

Ring system with 3 rings and 17 atoms

65 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
65
With full pages
14
Scaffold SMILES

O=C(c1ccccc1)c1cc2cccnc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cc2cccnc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

[3-Amino-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridin-2-yl](2,4-difluorophenyl)methanone chemical structure, C17H14F2N2O2S, CAS 442872-55-1
[3-Amino-4-(methoxymethyl)-6-methylthieno[2,3-b]pyridin-2-yl](2,4-difluorophenyl)methanone
CAS 442872-55-1C17H14F2N2O2S
3,6-Diamino-2-(4-ethoxybenzoyl)-4-ethylthieno[2,3-b]pyridine-5-carbonitrile chemical structure, C19H18N4O2S, CAS 402953-47-3
3,6-Diamino-2-(4-ethoxybenzoyl)-4-ethylthieno[2,3-b]pyridine-5-carbonitrile
CAS 402953-47-3C19H18N4O2S
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-bromophenyl)methanone chemical structure, C17H15BrN2OS, CAS 312316-45-3
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-bromophenyl)methanone
CAS 312316-45-3C17H15BrN2OS
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone chemical structure, C17H16N2OS, CAS 151693-80-0
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone
CAS 151693-80-0C17H16N2OS
4,6-Dimethyl-2-(4-methylbenzoyl)thieno[2,3-B]pyridin-3-amine chemical structure, C17H16N2OS, CAS 296798-87-3
4,6-Dimethyl-2-(4-methylbenzoyl)thieno[2,3-B]pyridin-3-amine
CAS 296798-87-3C17H16N2OS
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)phenylmethanone chemical structure, C16H14N2OS, CAS 52505-58-5
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)phenylmethanone
CAS 52505-58-5C16H14N2OS
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(3,4-dimethoxyphenyl)methanone chemical structure, C18H18N2O3S, CAS 311333-24-1
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(3,4-dimethoxyphenyl)methanone
CAS 311333-24-1C18H18N2O3S
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone chemical structure, C15H12N2OS, CAS 52505-54-1
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone
CAS 52505-54-1C15H12N2OS
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(p-tolyl)methanone chemical structure, C16H14N2OS, CAS 59488-70-9
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(p-tolyl)methanone
CAS 59488-70-9C16H14N2OS
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(4-nitrophenyl)methanone chemical structure, C15H11N3O3S, CAS 59488-71-0
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(4-nitrophenyl)methanone
CAS 59488-71-0C15H11N3O3S
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone chemical structure, C17H15ClN2OS, CAS 328113-37-7
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone
CAS 328113-37-7C17H15ClN2OS
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-nitrophenyl)methanone chemical structure, C17H15N3O3S, CAS 312318-61-9
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-nitrophenyl)methanone
CAS 312318-61-9C17H15N3O3S
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone chemical structure, C16H13ClN2OS, CAS 285986-83-6
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone
CAS 285986-83-6C16H13ClN2OS
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-fluorophenyl)methanone chemical structure, C16H13FN2OS, CAS 285986-95-0
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-fluorophenyl)methanone
CAS 285986-95-0C16H13FN2OS
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone chemical structure, C15H11ClN2OS, CAS 59488-69-6
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone
CAS 59488-69-6C15H11ClN2OS
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-methoxyphenyl)methanone chemical structure, C17H16N2O2S, CAS 299932-44-8
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-methoxyphenyl)methanone
CAS 299932-44-8C17H16N2O2S
(3-Amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-methoxyphenyl)methanone chemical structure, C19H20N2O2S, CAS 445385-15-9
(3-Amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(4-methoxyphenyl)methanone
CAS 445385-15-9C19H20N2O2S
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(2-hydroxyphenyl)methanone chemical structure, C16H14N2O2S, CAS 402954-17-0
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(2-hydroxyphenyl)methanone
CAS 402954-17-0C16H14N2O2S
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(2,4-dimethylphenyl)methanone chemical structure, C18H18N2OS, CAS 313550-89-9
(3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(2,4-dimethylphenyl)methanone
CAS 313550-89-9C18H18N2OS
3,6-Diamino-2-benzoyl-4-ethylthieno[2,3-b]pyridine-5-carbonitrile chemical structure, C17H14N4OS, CAS 184530-34-5
3,6-Diamino-2-benzoyl-4-ethylthieno[2,3-b]pyridine-5-carbonitrile
CAS 184530-34-5C17H14N4OS
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-methylphenyl)methanone chemical structure, C18H18N2OS, CAS 332045-92-8
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(4-methylphenyl)methanone
CAS 332045-92-8C18H18N2OS
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(4-bromophenyl)methanone chemical structure, C15H11BrN2OS, CAS 326915-48-4
(3-Amino-6-methylthieno[2,3-b]pyridin-2-yl)(4-bromophenyl)methanone
CAS 326915-48-4C15H11BrN2OS
(3-Amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(3-chlorophenyl)methanone chemical structure, C18H17ClN2OS, CAS 445382-63-8
(3-Amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(3-chlorophenyl)methanone
CAS 445382-63-8C18H17ClN2OS
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(3-methoxyphenyl)methanone chemical structure, C18H18N2O2S, CAS 445384-35-0
(3-Amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)(3-methoxyphenyl)methanone
CAS 445384-35-0C18H18N2O2S