Murcko scaffold
Cyclopropylbenzene scaffold
19,216 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 19,216
- With full pages
- 778
Scaffold SMILES
c1ccc(C2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,249 to 1,296 of 19,216 chemicals
Trans-2-(2-chlorophenyl)cyclopropane-1-carboxylic acid
CAS 515179-18-7C10H9ClO2
(1S,2S)-2-(2,4-Dichlorophenyl)cyclopropanecarboxylic Acid
CAS 2165380-28-7C10H8Cl2O2
(1S,2S)-2-(m-Tolyl)cyclopropanecarboxylic Acid
CAS 1808782-69-5C11H12O2
(1S,2S)-2-(o-Tolyl)cyclopropanecarboxylic Acid
CAS 1821747-79-8C11H12O2
(1S,2S)-2-(3-Bromophenyl)cyclopropanecarboxylic Acid
CAS 2165565-11-5C10H9BrO2
1-((1S,2S)-2-(3-Bromophenyl)cyclopropyl)ethanone
CAS 2165532-10-3C11H11BrO
(1S,2S)-2-(4-Ethoxyphenyl)cyclopropanecarboxylic Acid
CAS 1375110-45-4C12H14O3
![[1-(3-Methylphenyl)cyclopropyl]methanamine chemical structure, C11H15N, CAS 886366-00-3](/s/CYGQQOPZCFJBKI-UHFFFAOYSA-N.svg)
[1-(3-Methylphenyl)cyclopropyl]methanamine
CAS 886366-00-3C11H15N
![1-[4-(Difluoromethoxy)phenyl]cyclopropane-1-carbonitrile chemical structure, C11H9F2NO, CAS 1039951-34-2](/s/LGCWEUNVNKMALH-UHFFFAOYSA-N.svg)
1-[4-(Difluoromethoxy)phenyl]cyclopropane-1-carbonitrile
CAS 1039951-34-2C11H9F2NO
1-(2,6-Dichlorophenyl)cyclopropane-1-carboxylic acid
CAS 1039931-24-2C10H8Cl2O2
1-(2-Chloro-6-fluorophenyl)cyclopropane-1-carboxylic acid
CAS 1006876-25-0C10H8ClFO2
![1-[4-(Difluoromethoxy)phenyl]cyclopropanecarboxylic acid chemical structure, C11H10F2O3, CAS 869969-80-2](/s/DQNRGZCUQITTFW-UHFFFAOYSA-N.svg)
1-[4-(Difluoromethoxy)phenyl]cyclopropanecarboxylic acid
CAS 869969-80-2C11H10F2O3
1-(2-Methoxy-5-methylphenyl)cyclopropane-1-carboxylic acid
CAS 1038719-04-8C12H14O3
1-(5-Chloro-2-methoxyphenyl)cyclopropane-1-carboxylic acid
CAS 1039952-36-7C11H11ClO3
1-(2,6-Dichlorophenyl)cyclopropanemethanamine
CAS 1039952-66-3C10H11Cl2N
1-(2-Chloro-6-fluorophenyl)cyclopropanemethanamine
CAS 1039952-82-3C10H11ClFN
(1-(4-Bromophenyl)cyclopropyl)methanamine
CAS 771583-34-7C10H12BrN
(1-(4-(Difluoromethoxy)phenyl)cyclopropyl)methanamine
CAS 1037131-62-6C11H13F2NO
![1-[1-(2-Methoxy-5-methylphenyl)cyclopropyl]methanamine chemical structure, C12H17NO, CAS 1039932-60-9](/s/YEIUKPCCMUKGPG-UHFFFAOYSA-N.svg)
1-[1-(2-Methoxy-5-methylphenyl)cyclopropyl]methanamine
CAS 1039932-60-9C12H17NO
![{1-[3-(Trifluoromethyl)phenyl]cyclopropyl}methanamine chemical structure, C11H12F3N, CAS 886365-96-4](/s/QLNBDTJGDJMHKX-UHFFFAOYSA-N.svg)
{1-[3-(Trifluoromethyl)phenyl]cyclopropyl}methanamine
CAS 886365-96-4C11H12F3N
(1-(5-Chloro-2-methoxyphenyl)cyclopropyl)methanamine
CAS 1039953-30-4C11H14ClNO
1-(3-Methoxy-4-methylphenyl)cyclopropanemethanamine
CAS 1039953-38-2C12H17NO
(1-(4-Ethoxyphenyl)cyclopropyl)methanamine
CAS 1039953-46-2C12H17NO
![1-{1-[4-(Propan-2-yl)phenyl]cyclopropyl}methanamine chemical structure, C13H19N, CAS 1039933-13-5](/s/PMKGMEVZLXNDJJ-UHFFFAOYSA-N.svg)
1-{1-[4-(Propan-2-yl)phenyl]cyclopropyl}methanamine
CAS 1039933-13-5C13H19N
- 1-[(1R,2R)-2-(2-Chlorophenyl)cyclopropyl]ethanone2287247-81-6C11H11ClO
- Rac-1-[(1r,2r)-2-(3-methoxyphenyl)cyclopropyl]ethan-1-one30625-64-0C12H14O2
- Rel-(1R,2S)-2-fluoro-2-phenylcyclopropane-1-carboxylic acid309242-46-4C10H9FO2
- (1R,2R)-2-(3-Chlorophenyl)cyclopropan-1-amine2351191-14-3C9H10ClN
- Trans-2-(3-chlorophenyl)cyclopropan-1-amine131844-30-9C9H10ClN
- Methyl (1S,2S)-2-(4-methoxyphenyl)cyclopropane-1-carboxylate1089180-61-9C12H14O3
- cis-2-(4-Fluorophenyl)cyclopropanecarboxylic acid950588-81-5C10H9FO2
- 1-(4-Bromophenyl)-N-(2-methoxyethyl)cyclopropane-1-carboxamide1210188-00-3C13H16BrNO2
- 1-(3,4-Dibromophenyl)cyclopropanecarboxylic acid939793-17-6C10H8Br2O2
- 1-(3-Chlorophenyl)-N-(2-(methylamino)-2-oxoethyl)cyclopropane-1-carboxamide1222982-89-9C13H15ClN2O2
- (1R,2S)-2-(4-Bromophenyl)cyclopropan-1-amine757879-02-0C9H10BrN
- 1-(4-Bromophenyl)-N-isobutylcyclopropane-1-carboxamide1456249-69-6C14H18BrNO
- 1-(4-Bromophenyl)-N-(prop-2-YN-1-yl)cyclopropane-1-carboxamide2149541-48-8C13H12BrNO
- (1S,2S)-2-Phenylcyclopropane-1-carbonitrile68907-36-8C10H9N
- rac-(1R,2S)-2-(3,4,5-Trimethoxyphenyl)cyclopropan-1-amineC12H17NO3
- Trimethoxytranylcypromine20186-45-2C12H17NO3
- 1-(2,4-Dichlorophenyl)cyclopropane-1-carboxamide56427-85-1C10H9Cl2NO
- (1R,2S)-2-(2-Chlorophenyl)cyclopropane-1-carboxylic acid2137029-16-2C10H9ClO2
- (1R,2S)-2-(2-Fluorophenyl)cyclopropane-1-carboxylic acid2350834-33-0C10H9FO2
- (1R,2R)-2-(2-Fluorophenyl)cyclopropanecarboxylic acid175168-71-5C10H9FO2
- (1R,2S)-2-(M-Tolyl)cyclopropane-1-carboxylic acid2226372-28-5C11H12O2
- rac-1-[(1R,2R)-2-(3-Methylphenyl)cyclopropyl]ethan-1-one1218670-29-1C12H14O
- rac-(1R,2R)-2-(4-Ethylphenyl)cyclopropane-1-carboxylic acid1218693-48-1C12H14O2
- Rac-1-[(1r,2r)-2-(4-ethylphenyl)cyclopropyl]ethan-1-one1218357-37-9C13H16O
Related scaffolds
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C1CCC(C2CC2)CC115 chemicals
C1CC(C2CC2)CCO111 chemicals![Scaffold O=c1ccnc(C2CC2)[nH]1](/scaffold/HADXIKCWXJVQEO-UHFFFAOYSA-N/structure.svg)
O=c1ccnc(C2CC2)[nH]111 chemicals