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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
6
Scaffold SMILES

O=c1[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-2,4-dimethylbenzenesulfonamide chemical structure, C17H19N3O3S, CAS 831239-84-0
N-(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-2,4-dimethylbenzenesulfonamide
CAS 831239-84-0C17H19N3O3S
N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-2-nitrobenzenesulfonamide chemical structure, C15H14N4O5S, CAS 830353-13-4
N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-2-nitrobenzenesulfonamide
CAS 830353-13-4C15H14N4O5S
N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-4-methylbenzenesulfonamide chemical structure, C16H17N3O3S, CAS 831188-51-3
N-(1,3-Dimethyl-2-oxobenzimidazol-5-yl)-4-methylbenzenesulfonamide
CAS 831188-51-3C16H17N3O3S
N-[6-(Dimethylamino)-1,3-dimethyl-2-oxobenzimidazol-5-yl]benzenesulfonamide chemical structure, C17H20N4O3S, CAS 874587-34-5
N-[6-(Dimethylamino)-1,3-dimethyl-2-oxobenzimidazol-5-yl]benzenesulfonamide
CAS 874587-34-5C17H20N4O3S
2,5-Dimethyl-N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzenesulfonamide chemical structure, C15H15N3O3S, CAS 869466-16-0
2,5-Dimethyl-N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzenesulfonamide
CAS 869466-16-0C15H15N3O3S
3-Chloro-4-fluoro-N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzenesulfonamide chemical structure, C13H9ClFN3O3S, CAS 872193-30-1
3-Chloro-4-fluoro-N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzenesulfonamide
CAS 872193-30-1C13H9ClFN3O3S
4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-benzenesulfonamide chemical structure, C17H18BrN3O4S, CAS 919973-83-4
4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-benzenesulfonamide
CAS 919973-83-4C17H18BrN3O4S
3-[(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoic acid chemical structure, C16H15N3O5S, CAS 2793042-00-7
3-[(1,3-Dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoic acid
CAS 2793042-00-7C16H15N3O5S
2-Bromo-N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide chemical structure, C15H14BrN3O3S, CAS 1243054-00-3
2-Bromo-N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide
CAS 1243054-00-3C15H14BrN3O3S
N-[(4-Methylphenyl)sulfonyl]-N-(2-oxo-1,3-dipropyl-2,3-dihydro-1H-benzimidazol-5-yl)glycine chemical structure, C22H27N3O5S, CAS 1713519-71-1
N-[(4-Methylphenyl)sulfonyl]-N-(2-oxo-1,3-dipropyl-2,3-dihydro-1H-benzimidazol-5-yl)glycine
CAS 1713519-71-1C22H27N3O5S