Murcko scaffold
Benzamide, N-2-thienyl- scaffold
930 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 930
- With full pages
- 52
Scaffold SMILES
O=C(Nc1cccs1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 529 to 576 of 930 chemicals
Methyl 2-(4-methoxybenzamido)thiophene-3-carboxylate
CAS 338750-45-1C14H13NO4S
![Propan-2-yl 5-(diethylcarbamoyl)-2-{[(3-fluorophenyl)carbonyl]amino}-4-methylthiophene-3-carboxylate chemical structure, C21H25FN2O4S, CAS 419559-36-7](/s/CMXBTGJHHYVTBN-UHFFFAOYSA-N.svg)
Propan-2-yl 5-(diethylcarbamoyl)-2-{[(3-fluorophenyl)carbonyl]amino}-4-methylthiophene-3-carboxylate
CAS 419559-36-7C21H25FN2O4S
![Ethyl 2-[[4-(dipropylsulfamoyl)benzoyl]amino]-5-ethylthiophene-3-carboxylate chemical structure, C22H30N2O5S2, CAS 312280-08-3](/s/DAJARUFFFHVSMQ-UHFFFAOYSA-N.svg)
Ethyl 2-[[4-(dipropylsulfamoyl)benzoyl]amino]-5-ethylthiophene-3-carboxylate
CAS 312280-08-3C22H30N2O5S2
![Propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-[(3,4,5-triethoxybenzoyl)amino]thiophene-3-carboxylate chemical structure, C27H38N2O7S, CAS 352690-92-7](/s/KVLDDUMOQYWGSH-UHFFFAOYSA-N.svg)
Propan-2-yl 5-(diethylcarbamoyl)-4-methyl-2-[(3,4,5-triethoxybenzoyl)amino]thiophene-3-carboxylate
CAS 352690-92-7C27H38N2O7S
![Ethyl 5-[(diethylamino)carbonyl]-4-methyl-2-[(3,4,5-trimethoxybenzoyl)amino]-3-thiophenecarboxylate chemical structure, C23H30N2O7S, CAS 347352-08-3](/s/ZOFZEOYVQLEKMK-UHFFFAOYSA-N.svg)
Ethyl 5-[(diethylamino)carbonyl]-4-methyl-2-[(3,4,5-trimethoxybenzoyl)amino]-3-thiophenecarboxylate
CAS 347352-08-3C23H30N2O7S
4-Ethyl 2-methyl 3-methyl-5-(3,4,5-triethoxybenzamido)thiophene-2,4-dicarboxylate
CAS 433966-14-4C23H29NO8S
2-(4-Chloro-benzoylamino)-4-isobutyl-thiophene-3-carboxylic acid
CAS 461438-06-2C16H16ClNO3S
![Dimethyl 3-methyl-5-[(3,4,5-triethoxybenzoyl)amino]thiophene-2,4-dicarboxylate chemical structure, C22H27NO8S, CAS 545343-53-1](/s/WQSSRFQIIKOBEA-UHFFFAOYSA-N.svg)
Dimethyl 3-methyl-5-[(3,4,5-triethoxybenzoyl)amino]thiophene-2,4-dicarboxylate
CAS 545343-53-1C22H27NO8S
![Ethyl 2-[(2-nitrobenzoyl)amino]-5-propyl-3-thiophenecarboxylate chemical structure, C17H18N2O5S, CAS 895967-55-2](/s/CRJYHFQNRYUEJY-UHFFFAOYSA-N.svg)
Ethyl 2-[(2-nitrobenzoyl)amino]-5-propyl-3-thiophenecarboxylate
CAS 895967-55-2C17H18N2O5S
Methyl 2-(3-methoxybenzamido)thiophene-3-carboxylate
CAS 830339-31-6C14H13NO4S
2-Chloro-N-(3-cyanothiophen-2-yl)-6-fluorobenzamide
CAS 895942-83-3C12H6ClFN2OS
![Ethyl 5-acetyl-2-{[(4-methoxy-3-nitrophenyl)carbonyl]amino}-4-methylthiophene-3-carboxylate chemical structure, C18H18N2O7S, CAS 774587-51-8](/s/OIWFCEZUOQGHFH-UHFFFAOYSA-N.svg)
Ethyl 5-acetyl-2-{[(4-methoxy-3-nitrophenyl)carbonyl]amino}-4-methylthiophene-3-carboxylate
CAS 774587-51-8C18H18N2O7S
2-Benzamidothiophene-3-carboxamide
CAS 55654-16-5C12H10N2O2S
![2-[(4-Methoxy-3-nitrobenzoyl)amino]-5-propylthiophene-3-carboxamide chemical structure, C16H17N3O5S, CAS 774587-50-7](/s/KGZFPXQYUZWMQP-UHFFFAOYSA-N.svg)
2-[(4-Methoxy-3-nitrobenzoyl)amino]-5-propylthiophene-3-carboxamide
CAS 774587-50-7C16H17N3O5S
![Methylethyl 2-[(3-chlorophenyl)carbonylamino]thiophene-3-carboxylate chemical structure, C15H14ClNO3S, CAS 895955-59-6](/s/AYUQXDPKHZRLPW-UHFFFAOYSA-N.svg)
Methylethyl 2-[(3-chlorophenyl)carbonylamino]thiophene-3-carboxylate
CAS 895955-59-6C15H14ClNO3S
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-methoxy-3-methylbenzamide
CAS 835899-30-4C16H16N2O2S
![Ethyl 4-cyano-5-[(2-methoxy-3-methylbenzoyl)amino]-3-methyl-2-thiophenecarboxylate chemical structure, C18H18N2O4S, CAS 839692-17-0](/s/KVWODKCSEJJHNA-UHFFFAOYSA-N.svg)
Ethyl 4-cyano-5-[(2-methoxy-3-methylbenzoyl)amino]-3-methyl-2-thiophenecarboxylate
CAS 839692-17-0C18H18N2O4S
3-Thiophenecarboxylic acid, 2-(benzoylamino)-5-methyl-, 2-hydroxyethyl ester
CAS 78033-82-6C15H15NO4S
3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-hydroxyethyl ester
CAS 78033-83-7C16H17NO4S
3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-(dimethylamino)ethyl ester
CAS 78033-84-8C18H22N2O3S
3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-(diethylamino)ethyl ester
CAS 78033-85-9C20H26N2O3S
2-Thiopheneacetic acid, 5-benzamido-4-carboxy-3-methyl-
CAS 105522-85-8C15H13NO5S
![Ethyl 5-acetyl-2-[(4-chlorobenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C17H16ClNO4S, CAS 299953-26-7](/s/LYSUOTFXXYTIQM-UHFFFAOYSA-N.svg)
Ethyl 5-acetyl-2-[(4-chlorobenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 299953-26-7C17H16ClNO4S
![Methyl 4-cyano-5-[(3,5-dimethylbenzoyl)amino]-3-methyl-2-thiophenecarboxylate chemical structure, C17H16N2O3S, CAS 723752-61-2](/s/LULJQDKNNUJSFF-UHFFFAOYSA-N.svg)
Methyl 4-cyano-5-[(3,5-dimethylbenzoyl)amino]-3-methyl-2-thiophenecarboxylate
CAS 723752-61-2C17H16N2O3S
- Methyl 2-benzamido-4,5-dimethylthiophene-3-carboxylate325698-04-2C15H15NO3S
- Methyl 2-(2-methylbenzamido)thiophene-3-carboxylate864940-26-1C14H13NO3S
- 2-(3-Nitrobenzamido)thiophene-3-carboxamide852702-70-6C12H9N3O4S
- 2-(4-Chlorobenzamido)-N-methylthiophene-3-carboxamide864974-80-1C13H11ClN2O2S
- Ethyl 4-methyl-5-(propionyloxy)-2-(3,4,5-triethoxybenzamido)thiophene-3-carboxylate398999-10-5C24H31NO8S
- Ethyl 5-(3,5-dichlorobenzamido)-3-methylthiophene-2-carboxylate380471-94-3C15H13Cl2NO3S
- 2-(4-Fluorobenzamido)-N-methylthiophene-3-carboxamide864941-39-9C13H11FN2O2S
- Ethyl 2-benzamidothiophene-3-carboxylate864940-42-1C14H13NO3S
- 2-(4-(N,N-Diethylsulfamoyl)benzamido)-N-methylthiophene-3-carboxamide864941-38-8C17H21N3O4S2
- 2-(4-Methoxybenzamido)-N-methylthiophene-3-carboxamide864941-43-5C14H14N2O3S
- 2-(2-Methoxybenzamido)thiophene-3-carboxamide864941-04-8C13H12N2O3S
- 2-(5-Chloro-2-nitrobenzamido)-4,5-dimethylthiophene-3-carboxamide540800-63-3C14H12ClN3O4S
- 2-(3-Chlorobenzamido)-N-methylthiophene-3-carboxamide864974-82-3C13H11ClN2O2S
- Dimethyl 5-({[5-bromo-2-(difluoromethoxy)phenyl]carbonyl}amino)-3-methylthiophene-2,4-dicarboxylate828287-12-3C17H14BrF2NO6S
- Methyl 2-(3-fluorobenzamido)thiophene-3-carboxylate864940-18-1C13H10FNO3S
- 2-(3,4-Dimethylbenzamido)-N-methylthiophene-3-carboxamide864974-65-2C15H16N2O2S
- Ethyl 2-(4-cyanobenzamido)thiophene-3-carboxylate864940-47-6C15H12N2O3S
- Diethyl 5-[({5-[(2-chloroethyl)(methyl)sulfamoyl]-2-methoxyphenyl}carbonyl)amino]-3-methylthiophene-2,4-dicarboxylate690246-50-5C22H27ClN2O8S2
- Ethyl 2-[4-(diethylsulfamoyl)benzamido]-4,5-dimethylthiophene-3-carboxylate325734-52-9C20H26N2O5S2
- Diethyl 5-(4-(N,N-diethylsulfamoyl)benzamido)-3-methylthiophene-2,4-dicarboxylate315677-60-2C22H28N2O7S2
- Diethyl 5-[[4-(dipropylsulfamoyl)benzoyl]amino]-3-methylthiophene-2,4-dicarboxylate392248-91-8C24H32N2O7S2
- Methyl 2-[(4-chlorobenzoyl)amino]-5-propylthiophene-3-carboxylate444998-52-1C16H16ClNO3S
- Methyl 2-(2,4-dichlorobenzamido)-4,5-dimethylthiophene-3-carboxylate551910-85-1C15H13Cl2NO3S
- N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3,5-dimethoxybenzamide438615-50-0C16H16N2O3S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals
O=C(Nc1ccccc1)C1CCCC143 chemicals