Murcko scaffold
Benzamide, N-2-thienyl- scaffold
930 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 930
- With full pages
- 52
Scaffold SMILES
O=C(Nc1cccs1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 193 to 240 of 930 chemicals
![Isopropyl 5-[(diethylamino)carbonyl]-2-[(2-fluorobenzoyl)amino]-4-methyl-3-thiophenecarboxylate chemical structure, C21H25FN2O4S, CAS 352704-37-1](/s/CLCQADJSVFCVIN-UHFFFAOYSA-N.svg)
Isopropyl 5-[(diethylamino)carbonyl]-2-[(2-fluorobenzoyl)amino]-4-methyl-3-thiophenecarboxylate
CAS 352704-37-1C21H25FN2O4S
![2-O-Methyl 4-O-propan-2-yl 5-[(2-ethoxybenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate chemical structure, C20H23NO6S, CAS 445000-19-1](/s/UABMEPQMVUVABX-UHFFFAOYSA-N.svg)
2-O-Methyl 4-O-propan-2-yl 5-[(2-ethoxybenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate
CAS 445000-19-1C20H23NO6S
![Ethyl 5-acetyl-2-[(4-isopropylbenzoyl)amino]-4-methyl-3-thiophenecarboxylate chemical structure, C20H23NO4S, CAS 540759-75-9](/s/XDIXOKCAWGRKJD-UHFFFAOYSA-N.svg)
Ethyl 5-acetyl-2-[(4-isopropylbenzoyl)amino]-4-methyl-3-thiophenecarboxylate
CAS 540759-75-9C20H23NO4S
![Methyl 2-[(2-chloro-5-nitrobenzoyl)amino]-5-propylthiophene-3-carboxylate chemical structure, C16H15ClN2O5S, CAS 445001-56-9](/s/IZLAJTUJYZJOAN-UHFFFAOYSA-N.svg)
Methyl 2-[(2-chloro-5-nitrobenzoyl)amino]-5-propylthiophene-3-carboxylate
CAS 445001-56-9C16H15ClN2O5S
![Isopropyl 4-(aminocarbonyl)-3-methyl-5-[(2-methylbenzoyl)amino]-2-thiophenecarboxylate chemical structure, C18H20N2O4S, CAS 353765-98-7](/s/CMQLVFFXPDNMKF-UHFFFAOYSA-N.svg)
Isopropyl 4-(aminocarbonyl)-3-methyl-5-[(2-methylbenzoyl)amino]-2-thiophenecarboxylate
CAS 353765-98-7C18H20N2O4S
![Isopropyl 2-({2-chloro-4-nitrobenzoyl}amino)-5-[(dimethylamino)carbonyl]-4-methylthiophene-3-carboxylate chemical structure, C19H20ClN3O6S, CAS 445002-51-7](/s/JMFKTNNFAWQXAU-UHFFFAOYSA-N.svg)
Isopropyl 2-({2-chloro-4-nitrobenzoyl}amino)-5-[(dimethylamino)carbonyl]-4-methylthiophene-3-carboxylate
CAS 445002-51-7C19H20ClN3O6S
Ethyl 2-({5-chloro-2-nitrobenzoyl}amino)-5-propyl-3-thiophenecarboxylate
CAS 515177-98-7C17H17ClN2O5S
4-Cyano-5-({3-nitrobenzoyl}amino)-N,N,3-trimethylthiophene-2-carboxamide
CAS 445004-34-2C16H14N4O4S
![Ethyl 2-[(4-nitrobenzoyl)amino]-5-propan-2-ylthiophene-3-carboxylate chemical structure, C17H18N2O5S, CAS 445004-44-4](/s/AVNJVNLYGMCCGB-UHFFFAOYSA-N.svg)
Ethyl 2-[(4-nitrobenzoyl)amino]-5-propan-2-ylthiophene-3-carboxylate
CAS 445004-44-4C17H18N2O5S
![Isopropyl 2-({4-chloro-3-nitrobenzoyl}amino)-5-[(diethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate chemical structure, C21H24ClN3O6S, CAS 544442-22-0](/s/WOEYTPDANMYIDC-UHFFFAOYSA-N.svg)
Isopropyl 2-({4-chloro-3-nitrobenzoyl}amino)-5-[(diethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate
CAS 544442-22-0C21H24ClN3O6S
![4-Isopropyl 2-methyl 5-[(2-chlorobenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate chemical structure, C18H18ClNO5S, CAS 445004-63-7](/s/YKHSTWCOVZSEOI-UHFFFAOYSA-N.svg)
4-Isopropyl 2-methyl 5-[(2-chlorobenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate
CAS 445004-63-7C18H18ClNO5S
![Isopropyl 2-[(4-ethoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate chemical structure, C19H23NO4S, CAS 544413-58-3](/s/NJNCACIHJUPGTH-UHFFFAOYSA-N.svg)
Isopropyl 2-[(4-ethoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate
CAS 544413-58-3C19H23NO4S
Methyl 2-({5-chloro-2-nitrobenzoyl}amino)-4,5-dimethyl-3-thiophenecarboxylate
CAS 540800-04-2C15H13ClN2O5S
![Isopropyl 2-[(2,3-difluorobenzoyl)amino]-4-ethyl-5-methyl-3-thiophenecarboxylate chemical structure, C18H19F2NO3S, CAS 353788-32-6](/s/ZYPFRPFLSOROFW-UHFFFAOYSA-N.svg)
Isopropyl 2-[(2,3-difluorobenzoyl)amino]-4-ethyl-5-methyl-3-thiophenecarboxylate
CAS 353788-32-6C18H19F2NO3S
![Ethyl 5-acetyl-2-[(2,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C19H21NO6S, CAS 541534-77-4](/s/ATOSVUBGUJIABT-UHFFFAOYSA-N.svg)
Ethyl 5-acetyl-2-[(2,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 541534-77-4C19H21NO6S
![Methyl 2-[(4-bromobenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate chemical structure, C15H14BrNO3S, CAS 541533-42-0](/s/TZKDUCWATWEJPT-UHFFFAOYSA-N.svg)
Methyl 2-[(4-bromobenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate
CAS 541533-42-0C15H14BrNO3S
4,5-Dimethyl-2-(3,4,5-trimethoxybenzamido)thiophene-3-carboxamide
CAS 433319-31-4C17H20N2O5S
![Isopropyl 2-({5-chloro-2-nitrobenzoyl}amino)-5-[(diethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate chemical structure, C21H24ClN3O6S, CAS 543715-18-0](/s/NVPIGYRLOQDRRD-UHFFFAOYSA-N.svg)
Isopropyl 2-({5-chloro-2-nitrobenzoyl}amino)-5-[(diethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate
CAS 543715-18-0C21H24ClN3O6S
![Methyl 2-[(3-bromobenzoyl)amino]-5-(dimethylcarbamoyl)-4-methylthiophene-3-carboxylate chemical structure, C17H17BrN2O4S, CAS 355003-44-0](/s/QWTSXOUGGAQLCY-UHFFFAOYSA-N.svg)
Methyl 2-[(3-bromobenzoyl)amino]-5-(dimethylcarbamoyl)-4-methylthiophene-3-carboxylate
CAS 355003-44-0C17H17BrN2O4S
![Diethyl 5-[(3-chlorobenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate chemical structure, C18H18ClNO5S, CAS 355003-81-5](/s/KJQFOQULKNKPKU-UHFFFAOYSA-N.svg)
Diethyl 5-[(3-chlorobenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate
CAS 355003-81-5C18H18ClNO5S
![Ethyl 2-(benzoylamino)-5-[(dimethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate chemical structure, C18H20N2O4S, CAS 353769-66-1](/s/ANPRROGCRKFNFT-UHFFFAOYSA-N.svg)
Ethyl 2-(benzoylamino)-5-[(dimethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate
CAS 353769-66-1C18H20N2O4S
![Ethyl 4-(aminocarbonyl)-5-[(2-fluorobenzoyl)amino]-3-methyl-2-thiophenecarboxylate chemical structure, C16H15FN2O4S, CAS 353769-98-9](/s/JNQZNQHYIWDNJQ-UHFFFAOYSA-N.svg)
Ethyl 4-(aminocarbonyl)-5-[(2-fluorobenzoyl)amino]-3-methyl-2-thiophenecarboxylate
CAS 353769-98-9C16H15FN2O4S
![Ethyl 2-[(2,4-dimethoxybenzoyl)amino]-4-ethyl-5-methyl-3-thiophenecarboxylate chemical structure, C19H23NO5S, CAS 541542-82-9](/s/TZTPIYAOWIPOIF-UHFFFAOYSA-N.svg)
Ethyl 2-[(2,4-dimethoxybenzoyl)amino]-4-ethyl-5-methyl-3-thiophenecarboxylate
CAS 541542-82-9C19H23NO5S
![Methyl 5-[(diethylamino)carbonyl]-2-({4-nitro-3-methylbenzoyl}amino)-4-methyl-3-thiophenecarboxylate chemical structure, C20H23N3O6S, CAS 543684-55-5](/s/NAPNMUGLIZEQNB-UHFFFAOYSA-N.svg)
Methyl 5-[(diethylamino)carbonyl]-2-({4-nitro-3-methylbenzoyl}amino)-4-methyl-3-thiophenecarboxylate
CAS 543684-55-5C20H23N3O6S
- Ethyl 2-[(2-chloro-4,5-difluorobenzoyl)amino]-5-[(diethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate438476-19-8C20H21ClF2N2O4S
- Methyl 2-[(5-chloro-2-nitrobenzoyl)amino]-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate445285-64-3C19H20ClN3O6S
- Diethyl 5-[(3,5-difluorobenzoyl)amino]-3-methyl-2,4-thiophenedicarboxylate445287-66-1C18H17F2NO5S
- 2-[(3-Bromo-4-methoxybenzoyl)amino]-4,5-dimethylthiophene-3-carboxamide433305-89-6C15H15BrN2O3S
- 2-[(3-Iodo-4-methylbenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide497089-84-6C15H15IN2O2S
- Methyl 2-[(4-chloro-3-nitrobenzoyl)amino]-5-methylthiophene-3-carboxylate445005-10-7C14H11ClN2O5S
- Ethyl 2-({4-chloro-2-nitrobenzoyl}amino)-5-isopropylthiophene-3-carboxylate445006-46-2C17H17ClN2O5S
- Methyl 2-[(3-iodobenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate445006-74-6C15H14INO3S
- Methyl 5-(diethylcarbamoyl)-2-[(3,5-dimethylbenzoyl)amino]-4-methylthiophene-3-carboxylate445007-54-5C21H26N2O4S
- Methyl 2-[(4-isopropoxybenzoyl)amino]-5-isopropyl-3-thiophenecarboxylate445008-30-0C19H23NO4S
- 4-Ethyl 2-methyl 5-{[(2,6-dimethoxyphenyl)carbonyl]amino}-3-methylthiophene-2,4-dicarboxylate702649-50-1C19H21NO7S
- 4-Cyano-N,N,3-trimethyl-5-[(3,4,5-triethoxybenzoyl)amino]thiophene-2-carboxamide444934-90-1C22H27N3O5S
- Ethyl 2-[(4-isopropoxybenzoyl)amino]-5-propylthiophene-3-carboxylate444937-38-6C20H25NO4S
- 2-O-Methyl 4-O-propan-2-yl 5-[(3-ethoxybenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate495381-97-0C20H23NO6S
- Methyl 2-[(5-chloro-2-methoxybenzoyl)amino]-5-propylthiophene-3-carboxylate445013-37-6C17H18ClNO4S
- Methyl 2-[(4-bromobenzoyl)amino]-5-propyl-3-thiophenecarboxylate445013-49-0C16H16BrNO3S
- Ethyl 2-[(3,4-dimethoxybenzoyl)amino]-5-propan-2-ylthiophene-3-carboxylate445013-95-6C19H23NO5S
- Ethyl 5-(dimethylcarbamoyl)-2-[(2-iodobenzoyl)amino]-4-methylthiophene-3-carboxylate515120-68-0C18H19IN2O4S
- Methyl 2-[(3-iodobenzoyl)amino]-5-isopropyl-3-thiophenecarboxylate445014-31-3C16H16INO3S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-5-methyl-, 2-hydroxyethyl ester78033-82-6C15H15NO4S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-hydroxyethyl ester78033-83-7C16H17NO4S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-(dimethylamino)ethyl ester78033-84-8C18H22N2O3S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-(diethylamino)ethyl ester78033-85-9C20H26N2O3S
- 2-Thiopheneacetic acid, 5-benzamido-4-carboxy-3-methyl-105522-85-8C15H13NO5S
Related scaffolds
Same ring framework with different atoms or bond orders
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