Murcko scaffold
Benzamide, N-2-thienyl- scaffold
930 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 930
- With full pages
- 52
Scaffold SMILES
O=C(Nc1cccs1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 289 to 336 of 930 chemicals
![Ethyl 5-(diethylcarbamoyl)-2-[(2,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C22H28N2O6S, CAS 5702-17-0](/s/DWCPKOVERUHIIC-UHFFFAOYSA-N.svg)
Ethyl 5-(diethylcarbamoyl)-2-[(2,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 5702-17-0C22H28N2O6S
![Dimethyl 5-[(3,5-dimethoxybenzoyl)amino]-3-methyl-2,4-thiophenedicarboxylate chemical structure, C18H19NO7S, CAS 353783-53-6](/s/PSWWLJIYHSYOQG-UHFFFAOYSA-N.svg)
Dimethyl 5-[(3,5-dimethoxybenzoyl)amino]-3-methyl-2,4-thiophenedicarboxylate
CAS 353783-53-6C18H19NO7S
![Ethyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate chemical structure, C17H18ClNO3S, CAS 353784-37-9](/s/VDXCKWPYZQJBKO-UHFFFAOYSA-N.svg)
Ethyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate
CAS 353784-37-9C17H18ClNO3S
![Dimethyl 5-[(4-chlorobenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate chemical structure, C16H14ClNO5S, CAS 353784-82-4](/s/PWEPMTBYOTWEPQ-UHFFFAOYSA-N.svg)
Dimethyl 5-[(4-chlorobenzoyl)amino]-3-methylthiophene-2,4-dicarboxylate
CAS 353784-82-4C16H14ClNO5S
![Ethyl 4-(aminocarbonyl)-5-[(2,4-dichlorobenzoyl)amino]-3-methyl-2-thiophenecarboxylate chemical structure, C16H14Cl2N2O4S, CAS 5692-61-5](/s/OZSRLENOPJHVAO-UHFFFAOYSA-N.svg)
Ethyl 4-(aminocarbonyl)-5-[(2,4-dichlorobenzoyl)amino]-3-methyl-2-thiophenecarboxylate
CAS 5692-61-5C16H14Cl2N2O4S
![Diisopropyl 5-[(3,4-dimethoxybenzoyl)amino]-3-methyl-2,4-thiophenedicarboxylate chemical structure, C22H27NO7S, CAS 353785-86-1](/s/YVZJXFFUVMPNSH-UHFFFAOYSA-N.svg)
Diisopropyl 5-[(3,4-dimethoxybenzoyl)amino]-3-methyl-2,4-thiophenedicarboxylate
CAS 353785-86-1C22H27NO7S
![Methyl 5-(diethylcarbamoyl)-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C20H24N2O5S, CAS 353787-40-3](/s/CVTCJQMSLNAEPG-UHFFFAOYSA-N.svg)
Methyl 5-(diethylcarbamoyl)-2-[(4-methoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 353787-40-3C20H24N2O5S
Ethyl 2-(2,5-dichlorobenzamido)-4,5-dimethylthiophene-3-carboxylate
CAS 353470-44-7C16H15Cl2NO3S
![Isopropyl 5-[(diethylamino)carbonyl]-2-[(4-ethoxybenzoyl)amino]-4-methyl-3-thiophenecarboxylate chemical structure, C23H30N2O5S, CAS 353471-24-6](/s/UYUWFFROYDLRGK-UHFFFAOYSA-N.svg)
Isopropyl 5-[(diethylamino)carbonyl]-2-[(4-ethoxybenzoyl)amino]-4-methyl-3-thiophenecarboxylate
CAS 353471-24-6C23H30N2O5S
![Ethyl 2-[(3,5-dimethoxybenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate chemical structure, C19H23NO5S, CAS 352678-37-6](/s/RGXOOIYBJIOSMD-UHFFFAOYSA-N.svg)
Ethyl 2-[(3,5-dimethoxybenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate
CAS 352678-37-6C19H23NO5S
![Isopropyl 2-[(4-chlorobenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate chemical structure, C17H18ClNO3S, CAS 352678-56-9](/s/FDGQZDHYGAVVIW-UHFFFAOYSA-N.svg)
Isopropyl 2-[(4-chlorobenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate
CAS 352678-56-9C17H18ClNO3S
![Isopropyl 2-[(3-chlorobenzoyl)amino]-4-ethyl-5-methyl-3-thiophenecarboxylate chemical structure, C18H20ClNO3S, CAS 352678-57-0](/s/BMQPIUHXFQEPCL-UHFFFAOYSA-N.svg)
Isopropyl 2-[(3-chlorobenzoyl)amino]-4-ethyl-5-methyl-3-thiophenecarboxylate
CAS 352678-57-0C18H20ClNO3S
1-Methylethyl 5-((diethylamino)carbonyl)-4-methyl-2-((3-methyl-4-nitrobenzoyl)amino)-3-thiophenecarboxylate
CAS 420092-68-8C22H27N3O6S
![Methyl 2-[(2,5-dichlorobenzoyl)amino]-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate chemical structure, C19H20Cl2N2O4S, CAS 438612-86-3](/s/UFOVCKXFEZFQAO-UHFFFAOYSA-N.svg)
Methyl 2-[(2,5-dichlorobenzoyl)amino]-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate
CAS 438612-86-3C19H20Cl2N2O4S
Ethyl 4-cyano-5-(3,4-dimethoxybenzamido)-3-methylthiophene-2-carboxylate
CAS 354994-86-8C18H18N2O5S
![Ethyl 4-carbamoyl-5-[(4-methoxybenzoyl)amino]-3-methylthiophene-2-carboxylate chemical structure, C17H18N2O5S, CAS 438614-64-3](/s/FCADOSCBRYTHKO-UHFFFAOYSA-N.svg)
Ethyl 4-carbamoyl-5-[(4-methoxybenzoyl)amino]-3-methylthiophene-2-carboxylate
CAS 438614-64-3C17H18N2O5S
Methyl 4-ethyl-2-({3-nitro-2-methylbenzoyl}amino)-5-methyl-3-thiophenecarboxylate
CAS 557779-91-6C17H18N2O5S
Diethyl 5-(3,4-dimethylbenzamido)-3-methylthiophene-2,4-dicarboxylate
CAS 352682-20-3C20H23NO5S
![Ethyl 5-[(diethylamino)carbonyl]-2-[(3-fluorobenzoyl)amino]-4-methyl-3-thiophenecarboxylate chemical structure, C20H23FN2O4S, CAS 339362-62-8](/s/HCFQAIVNMBSOCM-UHFFFAOYSA-N.svg)
Ethyl 5-[(diethylamino)carbonyl]-2-[(3-fluorobenzoyl)amino]-4-methyl-3-thiophenecarboxylate
CAS 339362-62-8C20H23FN2O4S
![Methyl 5-(diethylcarbamoyl)-2-[(3,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C21H26N2O6S, CAS 352686-33-0](/s/UFCDFQZZNSUSEE-UHFFFAOYSA-N.svg)
Methyl 5-(diethylcarbamoyl)-2-[(3,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 352686-33-0C21H26N2O6S
![Ethyl 2-[(2,6-dichlorobenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate chemical structure, C16H15Cl2NO3S, CAS 550353-46-3](/s/FOYQWLQBRCHNOM-UHFFFAOYSA-N.svg)
Ethyl 2-[(2,6-dichlorobenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxylate
CAS 550353-46-3C16H15Cl2NO3S
![Ethyl 5-carbamoyl-2-[(4-chlorobenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C16H15ClN2O4S, CAS 550354-53-5](/s/BYYFOWNUZJUMPE-UHFFFAOYSA-N.svg)
Ethyl 5-carbamoyl-2-[(4-chlorobenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 550354-53-5C16H15ClN2O4S
![Ethyl 5-(diethylcarbamoyl)-2-[(3,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate chemical structure, C22H28N2O6S, CAS 424805-57-2](/s/HDDFQPDVCNWWCB-UHFFFAOYSA-N.svg)
Ethyl 5-(diethylcarbamoyl)-2-[(3,4-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate
CAS 424805-57-2C22H28N2O6S
![4-Cyano-5-[(2,6-dimethoxybenzoyl)amino]-N,N-diethyl-3-methyl-2-thiophenecarboxamide chemical structure, C20H23N3O4S, CAS 353475-46-4](/s/HVUFJKLYACFHPH-UHFFFAOYSA-N.svg)
4-Cyano-5-[(2,6-dimethoxybenzoyl)amino]-N,N-diethyl-3-methyl-2-thiophenecarboxamide
CAS 353475-46-4C20H23N3O4S
- Propan-2-yl 2-(2-chlorobenzamido)-4-ethyl-5-methylthiophene-3-carboxylate6126-51-8C18H20ClNO3S
- Dimethyl 5-{[(3-fluorophenyl)carbonyl]amino}-3-methylthiophene-2,4-dicarboxylate424810-75-3C16H14FNO5S
- Methyl 5-(diethylcarbamoyl)-2-[(3,5-dimethoxybenzoyl)amino]-4-methylthiophene-3-carboxylate353479-39-7C21H26N2O6S
- Ethyl 2-[(4-bromobenzoyl)amino]-5-carbamoyl-4-methylthiophene-3-carboxylate353479-60-4C16H15BrN2O4S
- Methyl 4,5-dimethyl-2-[(3,4,5-triethoxybenzoyl)amino]thiophene-3-carboxylate352690-82-5C21H27NO6S
- Ethyl 4,5-dimethyl-2-[(3,4,5-triethoxybenzoyl)amino]-3-thiophenecarboxylate352692-43-4C22H29NO6S
- Methyl 2-{[(4-tert-butylphenyl)carbonyl]amino}-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate424809-80-3C23H30N2O4S
- Ethyl 5-(diethylcarbamoyl)-4-methyl-2-[(3-methyl-4-nitrobenzoyl)amino]thiophene-3-carboxylate541518-45-0C21H25N3O6S
- Methyl 2-[(4-chloro-2-nitrobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate540521-06-0C16H15ClN2O5S
- Isopropyl 2-[(3-bromobenzoyl)amino]-5-[(diethylamino)carbonyl]-4-methyl-3-thiophenecarboxylate544466-93-5C21H25BrN2O4S
- Isopropyl 5-[(diethylamino)carbonyl]-2-[(3,5-dimethoxybenzoyl)amino]-4-methyl-3-thiophenecarboxylate352700-35-7C23H30N2O6S
- 4,5-Dimethyl-2-[(3,4,5-triethoxybenzoyl)amino]thiophene-3-carboxamide353768-87-3C20H26N2O5S
- Methyl 4-(aminocarbonyl)-5-[(3,4-dichlorobenzoyl)amino]-3-methyl-2-thiophenecarboxylate353774-44-4C15H12Cl2N2O4S
- 2-[(2-Iodobenzoyl)amino]-4,5-dimethylthiophene-3-carboxylic acid342594-96-1C14H12INO3S
- N-(3-Cyano-4-ethyl-5-methylthiophen-2-yl)-2,3-dimethoxybenzamide445004-57-9C17H18N2O3S
- Methyl 2-({[2-chloro-5-(methylsulfanyl)phenyl]carbonyl}amino)-5-(dimethylcarbamoyl)-4-methylthiophene-3-carboxylate515122-88-0C18H19ClN2O4S2
- Methyl 2-{[(2-methylphenyl)carbonyl]amino}-5-(propan-2-yl)thiophene-3-carboxylate445007-92-1C17H19NO3S
- Ethyl 2-[(2,5-dichlorobenzoyl)amino]-5-ethyl-3-thiophenecarboxylate495396-41-3C16H15Cl2NO3S
- Methyl 4,5-dimethyl-2-({3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}amino)-3-thiophenecarboxylate445258-29-7C19H19F4NO4S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-5-methyl-, 2-hydroxyethyl ester78033-82-6C15H15NO4S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-hydroxyethyl ester78033-83-7C16H17NO4S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-(dimethylamino)ethyl ester78033-84-8C18H22N2O3S
- 3-Thiophenecarboxylic acid, 2-(benzoylamino)-4,5-dimethyl-, 2-(diethylamino)ethyl ester78033-85-9C20H26N2O3S
- 2-Thiopheneacetic acid, 5-benzamido-4-carboxy-3-methyl-105522-85-8C15H13NO5S
Related scaffolds
Same ring framework with different atoms or bond orders
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