CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
21
With full pages
5
Scaffold SMILES

O=C(Nc1cccn(Cc2ccccc2)c1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccn(Cc2ccccc2)c1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-[5-Acetyl-1-[(4-chlorophenyl)methyl]-6-methyl-2-oxopyridin-3-yl]-4-chlorobenzamide chemical structure, C22H18Cl2N2O3, CAS 338774-98-4
N-[5-Acetyl-1-[(4-chlorophenyl)methyl]-6-methyl-2-oxopyridin-3-yl]-4-chlorobenzamide
CAS 338774-98-4C22H18Cl2N2O3
N-[5-Acetyl-1-(2,4-dichlorobenzyl)-6-methyl-2-oxo-1,2-dihydro-3-pyridinyl]-3-chlorobenzenecarboxamide chemical structure, C22H17Cl3N2O3, CAS 338775-01-2
N-[5-Acetyl-1-(2,4-dichlorobenzyl)-6-methyl-2-oxo-1,2-dihydro-3-pyridinyl]-3-chlorobenzenecarboxamide
CAS 338775-01-2C22H17Cl3N2O3
3,4-Dichloro-N-[1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H12Cl4N2O2, CAS 400086-15-9
3,4-Dichloro-N-[1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 400086-15-9C19H12Cl4N2O2
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methylbenzenecarboxamide chemical structure, C20H16Cl2N2O2, CAS 400086-16-0
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methylbenzenecarboxamide
CAS 400086-16-0C20H16Cl2N2O2
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-3-(trifluoromethyl)benzenecarboxamide chemical structure, C20H13Cl2F3N2O2, CAS 400086-17-1
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-3-(trifluoromethyl)benzenecarboxamide
CAS 400086-17-1C20H13Cl2F3N2O2
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-2-nitrobenzenecarboxamide chemical structure, C19H13Cl2N3O4, CAS 400086-18-2
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-2-nitrobenzenecarboxamide
CAS 400086-18-2C19H13Cl2N3O4
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methoxybenzenecarboxamide chemical structure, C20H16Cl2N2O3, CAS 400086-19-3
N-[1-(3,4-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methoxybenzenecarboxamide
CAS 400086-19-3C20H16Cl2N2O3
N-(5-Acetyl-1-benzyl-6-methyl-2-oxo-1,2-dihydro-3-pyridinyl)-4-methylbenzenecarboxamide chemical structure, C23H22N2O3, CAS 477864-89-4
N-(5-Acetyl-1-benzyl-6-methyl-2-oxo-1,2-dihydro-3-pyridinyl)-4-methylbenzenecarboxamide
CAS 477864-89-4C23H22N2O3
3,4-Dichloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H12Cl4N2O2, CAS 338784-11-5
3,4-Dichloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 338784-11-5C19H12Cl4N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methoxybenzenecarboxamide chemical structure, C20H16Cl2N2O3, CAS 338784-55-7
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methoxybenzenecarboxamide
CAS 338784-55-7C20H16Cl2N2O3
4-Chloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H13Cl3N2O2, CAS 338784-43-3
4-Chloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 338784-43-3C19H13Cl3N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H14Cl2N2O2, CAS 338784-03-5
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 338784-03-5C19H14Cl2N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-5-(trifluoromethyl)-1,2-dihydro-3-pyridinyl]-4-isopropoxybenzenecarboxamide chemical structure, C23H19Cl2F3N2O3, CAS 339025-21-7
N-[1-(2,6-Dichlorobenzyl)-2-oxo-5-(trifluoromethyl)-1,2-dihydro-3-pyridinyl]-4-isopropoxybenzenecarboxamide
CAS 339025-21-7C23H19Cl2F3N2O3
2,6-Dichloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H12Cl4N2O2, CAS 338784-15-9
2,6-Dichloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 338784-15-9C19H12Cl4N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-3-(trifluoromethyl)benzenecarboxamide chemical structure, C20H13Cl2F3N2O2, CAS 338784-19-3
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-3-(trifluoromethyl)benzenecarboxamide
CAS 338784-19-3C20H13Cl2F3N2O2
2,4-Dichloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H12Cl4N2O2, CAS 338784-07-9
2,4-Dichloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 338784-07-9C19H12Cl4N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methylbenzenecarboxamide chemical structure, C20H16Cl2N2O2, CAS 338784-51-3
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-4-methylbenzenecarboxamide
CAS 338784-51-3C20H16Cl2N2O2
2-Chloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide chemical structure, C19H13Cl3N2O2, CAS 338784-47-7
2-Chloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]benzenecarboxamide
CAS 338784-47-7C19H13Cl3N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-2-nitrobenzenecarboxamide chemical structure, C19H13Cl2N3O4, CAS 338784-59-1
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-2-nitrobenzenecarboxamide
CAS 338784-59-1C19H13Cl2N3O4
2-Chloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-5-(trifluoromethyl)-1,2-dihydro-3-pyridinyl]-4-fluorobenzenecarboxamide chemical structure, C20H11Cl3F4N2O2, CAS 339025-19-3
2-Chloro-N-[1-(2,6-dichlorobenzyl)-2-oxo-5-(trifluoromethyl)-1,2-dihydro-3-pyridinyl]-4-fluorobenzenecarboxamide
CAS 339025-19-3C20H11Cl3F4N2O2
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-2-(trifluoromethyl)benzenecarboxamide chemical structure, C20H13Cl2F3N2O2, CAS 338784-39-7
N-[1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinyl]-2-(trifluoromethyl)benzenecarboxamide
CAS 338784-39-7C20H13Cl2F3N2O2