CompoundList
Sign in
Murcko scaffold

1-Hydroxy-3-{[(phenylamino)thioxomethyl]amino}thiolan-1-one scaffold

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
18
With full pages
7
Scaffold SMILES

O=S1(=O)CCC(NC(=S)Nc2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Hydroxy-3-{[(phenylamino)thioxomethyl]amino}thiolan-1-one page
Murcko scaffold O=S1(=O)CCC(NC(=S)Nc2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-Hydroxy-3-{[(phenylamino)thioxomethyl]amino}thiolan-1-one chemical structure, C11H14N2O2S2, CAS 321580-53-4
1-Hydroxy-3-{[(phenylamino)thioxomethyl]amino}thiolan-1-one
CAS 321580-53-4C11H14N2O2S2
1-Hydroxy-3-{[(phenylamino)thioxomethyl]propylamino}thiolan-1-one chemical structure, C14H20N2O2S2, CAS 327079-18-5
1-Hydroxy-3-{[(phenylamino)thioxomethyl]propylamino}thiolan-1-one
CAS 327079-18-5C14H20N2O2S2
3-({[(4-Hydroxyphenyl)amino]thioxomethyl}amino)thiolane-1,1-dione chemical structure, C11H14N2O3S2, CAS 443652-96-8
3-({[(4-Hydroxyphenyl)amino]thioxomethyl}amino)thiolane-1,1-dione
CAS 443652-96-8C11H14N2O3S2
3-({[(4-Chlorophenyl)amino]thioxomethyl}amino)thiolane-1,1-dione chemical structure, C11H13ClN2O2S2, CAS 443652-92-4
3-({[(4-Chlorophenyl)amino]thioxomethyl}amino)thiolane-1,1-dione
CAS 443652-92-4C11H13ClN2O2S2
3-({[(4-Methylphenyl)amino]thioxomethyl}amino)thiolane-1,1-dione chemical structure, C12H16N2O2S2, CAS 507252-54-2
3-({[(4-Methylphenyl)amino]thioxomethyl}amino)thiolane-1,1-dione
CAS 507252-54-2C12H16N2O2S2
1-(1,1-Dioxothiolan-3-yl)-3-(4-methoxyphenyl)thiourea chemical structure, C12H16N2O3S2, CAS 507252-76-8
1-(1,1-Dioxothiolan-3-yl)-3-(4-methoxyphenyl)thiourea
CAS 507252-76-8C12H16N2O3S2
1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-(o-tolyl)thiourea chemical structure, C13H18N2O2S2, CAS 507255-91-6
1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-(o-tolyl)thiourea
CAS 507255-91-6C13H18N2O2S2
3-({[(1,1-Dioxothiolan-3-yl)amino]thioxomethyl}amino)benzoic acid chemical structure, C12H14N2O4S2, CAS 503561-56-6
3-({[(1,1-Dioxothiolan-3-yl)amino]thioxomethyl}amino)benzoic acid
CAS 503561-56-6C12H14N2O4S2
1-(4-Hydroxy-1,1-dioxidotetrahydrothiophen-3-yl)-1-(2-hydroxyethyl)-3-phenylthiourea chemical structure, C13H18N2O4S2, CAS 503561-62-4
1-(4-Hydroxy-1,1-dioxidotetrahydrothiophen-3-yl)-1-(2-hydroxyethyl)-3-phenylthiourea
CAS 503561-62-4C13H18N2O4S2
3-({[(3-Methylphenyl)amino]thioxomethyl}amino)thiolane-1,1-dione chemical structure, C12H16N2O2S2, CAS 507252-50-8
3-({[(3-Methylphenyl)amino]thioxomethyl}amino)thiolane-1,1-dione
CAS 507252-50-8C12H16N2O2S2
3-[({[3-(Dimethylamino)phenyl]amino}thioxomethyl)amino]thiolane-1,1-dione chemical structure, C13H19N3O2S2, CAS 321580-49-8
3-[({[3-(Dimethylamino)phenyl]amino}thioxomethyl)amino]thiolane-1,1-dione
CAS 321580-49-8C13H19N3O2S2
3-({[(4-Methoxyphenyl)amino]thioxomethyl}amino)-3-methylthiolane-1,1-dione chemical structure, C13H18N2O3S2, CAS 507256-32-8
3-({[(4-Methoxyphenyl)amino]thioxomethyl}amino)-3-methylthiolane-1,1-dione
CAS 507256-32-8C13H18N2O3S2
3-Methyl-3-{[(phenylamino)thioxomethyl]amino}thiolane-1,1-dione chemical structure, C12H16N2O2S2, CAS 507459-48-5
3-Methyl-3-{[(phenylamino)thioxomethyl]amino}thiolane-1,1-dione
CAS 507459-48-5C12H16N2O2S2
1-(3-Bromophenyl)-3-(1,1-dioxothiolan-3-yl)thiourea chemical structure, C11H13BrN2O2S2, CAS 443652-93-5
1-(3-Bromophenyl)-3-(1,1-dioxothiolan-3-yl)thiourea
CAS 443652-93-5C11H13BrN2O2S2
1-(4-Hydroxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)thiourea chemical structure, C12H16N2O3S2, CAS 507252-85-9
1-(4-Hydroxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)thiourea
CAS 507252-85-9C12H16N2O3S2
3-({[(3-Hydroxyphenyl)amino]thioxomethyl}amino)-3-methylthiolane-1,1-dione chemical structure, C12H16N2O3S2, CAS 507252-80-4
3-({[(3-Hydroxyphenyl)amino]thioxomethyl}amino)-3-methylthiolane-1,1-dione
CAS 507252-80-4C12H16N2O3S2
1-(4-Chloro-1,1-dioxidotetrahydrothiophen-3-yl)-3-(4-nitrophenyl)thiourea chemical structure, C11H12ClN3O4S2, CAS 946203-44-7
1-(4-Chloro-1,1-dioxidotetrahydrothiophen-3-yl)-3-(4-nitrophenyl)thiourea
CAS 946203-44-7C11H12ClN3O4S2
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(2-methoxy-5-nitrophenyl)thiourea chemical structure, C12H15N3O5S2, CAS 946259-62-7
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(2-methoxy-5-nitrophenyl)thiourea
CAS 946259-62-7C12H15N3O5S2