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Murcko scaffold

Ring system with 3 rings and 20 atoms

329 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
329
With full pages
5
Scaffold SMILES

O=S(=O)(Nc1ccc2c(c1)NCCC2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc2c(c1)NCCC2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 329 chemicals

N-(1-Acetyl-3,4-dihydro-2H-quinolin-7-yl)-4-ethylbenzenesulfonamide chemical structure, C19H22N2O3S, CAS 1026619-22-6
N-(1-Acetyl-3,4-dihydro-2H-quinolin-7-yl)-4-ethylbenzenesulfonamide
CAS 1026619-22-6C19H22N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-3-methylbenzenesulfonamide chemical structure, C20H24N2O3S, CAS 1021073-36-8
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-3-methylbenzenesulfonamide
CAS 1021073-36-8C20H24N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methylbenzenesulfonamide chemical structure, C20H24N2O3S, CAS 1005298-75-8
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methylbenzenesulfonamide
CAS 1005298-75-8C20H24N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-3,4-dimethylbenzenesulfonamide chemical structure, C21H26N2O3S, CAS 1005300-84-4
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-3,4-dimethylbenzenesulfonamide
CAS 1005300-84-4C21H26N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,4-dimethylbenzenesulfonamide chemical structure, C21H26N2O3S, CAS 1005298-77-0
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,4-dimethylbenzenesulfonamide
CAS 1005298-77-0C21H26N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,4,5-trimethylbenzenesulfonamide chemical structure, C22H28N2O3S, CAS 946370-05-4
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,4,5-trimethylbenzenesulfonamide
CAS 946370-05-4C22H28N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,4,6-trimethylbenzenesulfonamide chemical structure, C22H28N2O3S, CAS 1005300-88-8
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,4,6-trimethylbenzenesulfonamide
CAS 1005300-88-8C22H28N2O3S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C21H26N2O4S, CAS 1005298-79-2
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methoxy-3-methylbenzenesulfonamide
CAS 1005298-79-2C21H26N2O4S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2-methoxy-5-methylbenzenesulfonamide chemical structure, C21H26N2O4S, CAS 1005300-91-3
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2-methoxy-5-methylbenzenesulfonamide
CAS 1005300-91-3C21H26N2O4S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methoxybenzenesulfonamide chemical structure, C20H24N2O4S, CAS 1005298-81-6
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methoxybenzenesulfonamide
CAS 1005298-81-6C20H24N2O4S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,5-dimethoxybenzenesulfonamide chemical structure, C21H26N2O5S, CAS 1005300-94-6
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-2,5-dimethoxybenzenesulfonamide
CAS 1005300-94-6C21H26N2O5S
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-3,4-dimethoxybenzenesulfonamide chemical structure, C21H26N2O5S, CAS 941986-92-1
N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-3,4-dimethoxybenzenesulfonamide
CAS 941986-92-1C21H26N2O5S
3-Fluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methoxybenzenesulfonamide chemical structure, C20H23FN2O4S, CAS 1005300-97-9
3-Fluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)-4-methoxybenzenesulfonamide
CAS 1005300-97-9C20H23FN2O4S
5-Fluoro-2-methoxy-N-[1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide chemical structure, C20H23FN2O4S, CAS 1171987-03-3
5-Fluoro-2-methoxy-N-[1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide
CAS 1171987-03-3C20H23FN2O4S
4-Ethyl-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C21H26N2O3S, CAS 946220-83-3
4-Ethyl-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 946220-83-3C21H26N2O3S
4-Ethoxy-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C21H26N2O4S, CAS 1026290-91-4
4-Ethoxy-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 1026290-91-4C21H26N2O4S
2-Fluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C19H21FN2O3S, CAS 1005298-85-0
2-Fluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 1005298-85-0C19H21FN2O3S
3-Fluoro-N-[1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide chemical structure, C19H21FN2O3S, CAS 1005301-00-7
3-Fluoro-N-[1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide
CAS 1005301-00-7C19H21FN2O3S
4-Fluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C19H21FN2O3S, CAS 1005298-87-2
4-Fluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 1005298-87-2C19H21FN2O3S
2,5-Difluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C19H20F2N2O3S, CAS 946322-39-0
2,5-Difluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 946322-39-0C19H20F2N2O3S
4-Chloro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C19H21ClN2O3S, CAS 1005301-03-0
4-Chloro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 1005301-03-0C19H21ClN2O3S
2,4-Difluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C19H20F2N2O3S, CAS 1027840-24-9
2,4-Difluoro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 1027840-24-9C19H20F2N2O3S
3-Chloro-N-[1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide chemical structure, C19H21ClN2O3S, CAS 1005301-11-0
3-Chloro-N-[1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide
CAS 1005301-11-0C19H21ClN2O3S
2-Chloro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide chemical structure, C19H21ClN2O3S, CAS 1005298-95-2
2-Chloro-N-(1-isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)benzenesulfonamide
CAS 1005298-95-2C19H21ClN2O3S