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Murcko scaffold

Ring system with 2 rings and 23 atoms

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
23
Chemicals
21
With full pages
3
Scaffold SMILES

O=C(CCSCCC(=O)Nc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCSCCC(=O)Nc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

Iotasul chemical structure, C38H50I6N6O14S, CAS 71767-13-0
Iotasul
CAS 71767-13-0C38H50I6N6O14S
3-[3-(2,4-Dimethylanilino)-3-oxopropyl]sulfanyl-N-(2,4-dimethylphenyl)propanamide chemical structure, C22H28N2O2S, CAS 548448-41-5
3-[3-(2,4-Dimethylanilino)-3-oxopropyl]sulfanyl-N-(2,4-dimethylphenyl)propanamide
CAS 548448-41-5C22H28N2O2S
3-[3-(2-Fluoroanilino)-3-oxopropyl]sulfanyl-N-(2-fluorophenyl)propanamide chemical structure, C18H18F2N2O2S, CAS 548432-92-4
3-[3-(2-Fluoroanilino)-3-oxopropyl]sulfanyl-N-(2-fluorophenyl)propanamide
CAS 548432-92-4C18H18F2N2O2S
3-[3-(2,5-Dimethylanilino)-3-oxopropyl]sulfanyl-N-(2,5-dimethylphenyl)propanamide chemical structure, C22H28N2O2S, CAS 548467-22-7
3-[3-(2,5-Dimethylanilino)-3-oxopropyl]sulfanyl-N-(2,5-dimethylphenyl)propanamide
CAS 548467-22-7C22H28N2O2S
3-[3-(5-Chloro-2-methoxyanilino)-3-oxopropyl]sulfanyl-N-(5-chloro-2-methoxyphenyl)propanamide chemical structure, C20H22Cl2N2O4S, CAS 547761-59-1
3-[3-(5-Chloro-2-methoxyanilino)-3-oxopropyl]sulfanyl-N-(5-chloro-2-methoxyphenyl)propanamide
CAS 547761-59-1C20H22Cl2N2O4S
3,3'-Sulfanediylbis{N-[4-(dimethylamino)phenyl]propanamide} chemical structure, C22H30N4O2S, CAS 548435-66-1
3,3'-Sulfanediylbis{N-[4-(dimethylamino)phenyl]propanamide}
CAS 548435-66-1C22H30N4O2S
3-[3-(4-Methoxyanilino)-3-oxopropyl]sulfanyl-N-(4-methoxyphenyl)propanamide chemical structure, C20H24N2O4S, CAS 547747-73-9
3-[3-(4-Methoxyanilino)-3-oxopropyl]sulfanyl-N-(4-methoxyphenyl)propanamide
CAS 547747-73-9C20H24N2O4S
3-[3-Oxo-3-(2,4,6-trimethylanilino)propyl]sulfanyl-N-(2,4,6-trimethylphenyl)propanamide chemical structure, C24H32N2O2S, CAS 547729-11-3
3-[3-Oxo-3-(2,4,6-trimethylanilino)propyl]sulfanyl-N-(2,4,6-trimethylphenyl)propanamide
CAS 547729-11-3C24H32N2O2S
3-[3-(2-Methoxy-5-methylanilino)-3-oxopropyl]sulfanyl-N-(2-methoxy-5-methylphenyl)propanamide chemical structure, C22H28N2O4S, CAS 546119-03-3
3-[3-(2-Methoxy-5-methylanilino)-3-oxopropyl]sulfanyl-N-(2-methoxy-5-methylphenyl)propanamide
CAS 546119-03-3C22H28N2O4S
3-[3-(3-Acetylanilino)-3-oxopropyl]sulfanyl-N-(3-acetylphenyl)propanamide chemical structure, C22H24N2O4S, CAS 548452-59-1
3-[3-(3-Acetylanilino)-3-oxopropyl]sulfanyl-N-(3-acetylphenyl)propanamide
CAS 548452-59-1C22H24N2O4S
3-[3-(3-Fluoroanilino)-3-oxopropyl]sulfanyl-N-(3-fluorophenyl)propanamide chemical structure, C18H18F2N2O2S, CAS 548778-45-6
3-[3-(3-Fluoroanilino)-3-oxopropyl]sulfanyl-N-(3-fluorophenyl)propanamide
CAS 548778-45-6C18H18F2N2O2S
4-[3-[3-(4-Carbamoylanilino)-3-oxopropyl]sulfanylpropanoylamino]benzamide chemical structure, C20H22N4O4S, CAS 547745-24-4
4-[3-[3-(4-Carbamoylanilino)-3-oxopropyl]sulfanylpropanoylamino]benzamide
CAS 547745-24-4C20H22N4O4S
3-[3-(4-Ethylanilino)-3-oxopropyl]sulfanyl-N-(4-ethylphenyl)propanamide chemical structure, C22H28N2O2S, CAS 445254-13-7
3-[3-(4-Ethylanilino)-3-oxopropyl]sulfanyl-N-(4-ethylphenyl)propanamide
CAS 445254-13-7C22H28N2O2S
3-[3-(2-Methoxyanilino)-3-oxopropyl]sulfanyl-N-(2-methoxyphenyl)propanamide chemical structure, C20H24N2O4S, CAS 548469-57-4
3-[3-(2-Methoxyanilino)-3-oxopropyl]sulfanyl-N-(2-methoxyphenyl)propanamide
CAS 548469-57-4C20H24N2O4S
3-[3-(3-Chloro-2-methylanilino)-3-oxopropyl]sulfanyl-N-(3-chloro-2-methylphenyl)propanamide chemical structure, C20H22Cl2N2O2S, CAS 548483-23-4
3-[3-(3-Chloro-2-methylanilino)-3-oxopropyl]sulfanyl-N-(3-chloro-2-methylphenyl)propanamide
CAS 548483-23-4C20H22Cl2N2O2S
3-[3-(2,4-Dichloroanilino)-3-oxopropyl]sulfanyl-N-(2,4-dichlorophenyl)propanamide chemical structure, C18H16Cl4N2O2S, CAS 548779-83-5
3-[3-(2,4-Dichloroanilino)-3-oxopropyl]sulfanyl-N-(2,4-dichlorophenyl)propanamide
CAS 548779-83-5C18H16Cl4N2O2S
3-[3-(3-Ethylanilino)-3-oxopropyl]sulfanyl-N-(3-ethylphenyl)propanamide chemical structure, C22H28N2O2S, CAS 547721-80-2
3-[3-(3-Ethylanilino)-3-oxopropyl]sulfanyl-N-(3-ethylphenyl)propanamide
CAS 547721-80-2C22H28N2O2S
Methyl 2-[3-[3-(2-methoxycarbonylanilino)-3-oxopropyl]sulfanylpropanoylamino]benzoate chemical structure, C22H24N2O6S, CAS 548782-78-1
Methyl 2-[3-[3-(2-methoxycarbonylanilino)-3-oxopropyl]sulfanylpropanoylamino]benzoate
CAS 548782-78-1C22H24N2O6S
3-[3-(2-Ethoxyanilino)-3-oxopropyl]sulfanyl-N-(2-ethoxyphenyl)propanamide chemical structure, C22H28N2O4S, CAS 546118-98-3
3-[3-(2-Ethoxyanilino)-3-oxopropyl]sulfanyl-N-(2-ethoxyphenyl)propanamide
CAS 546118-98-3C22H28N2O4S
3-[3-(4-Ethoxyanilino)-3-oxopropyl]sulfanyl-N-(4-ethoxyphenyl)propanamide chemical structure, C22H28N2O4S, CAS 548449-13-4
3-[3-(4-Ethoxyanilino)-3-oxopropyl]sulfanyl-N-(4-ethoxyphenyl)propanamide
CAS 548449-13-4C22H28N2O4S
Ethyl 4-[3-[3-(4-ethoxycarbonylanilino)-3-oxopropyl]sulfanylpropanoylamino]benzoate chemical structure, C24H28N2O6S, CAS 548481-58-9
Ethyl 4-[3-[3-(4-ethoxycarbonylanilino)-3-oxopropyl]sulfanylpropanoylamino]benzoate
CAS 548481-58-9C24H28N2O6S