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Murcko scaffold

Ring system with 2 rings and 14 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
17
With full pages
3
Scaffold SMILES

C(=Cc1ccsc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ccsc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

Methyl 4-{[2-cyano-2-(thiophen-3-yl)eth-1-EN-1-yl]amino}benzoate chemical structure, C15H12N2O2S
Methyl 4-{[2-cyano-2-(thiophen-3-yl)eth-1-EN-1-yl]amino}benzoate
C15H12N2O2S
(Z)-3-(3-Methylsulfanylanilino)-2-thiophen-3-ylprop-2-enenitrile chemical structure, C14H12N2S2
(Z)-3-(3-Methylsulfanylanilino)-2-thiophen-3-ylprop-2-enenitrile
C14H12N2S2
3-(4-Fluoroanilino)-2-(3-thienyl)acrylonitrile chemical structure, C13H9FN2S, CAS 477851-22-2
3-(4-Fluoroanilino)-2-(3-thienyl)acrylonitrile
CAS 477851-22-2C13H9FN2S
3-(2,4-Dichloroanilino)-2-(3-thienyl)acrylonitrile chemical structure, C13H8Cl2N2S
3-(2,4-Dichloroanilino)-2-(3-thienyl)acrylonitrile
C13H8Cl2N2S
Methyl 4-((2-cyano-2-(3-thienyl)vinyl)amino)benzoate chemical structure, C15H12N2O2S
Methyl 4-((2-cyano-2-(3-thienyl)vinyl)amino)benzoate
C15H12N2O2S
3-Anilino-2-(3-thienyl)acrylonitrile chemical structure, C13H10N2S, CAS 1164503-74-5
3-Anilino-2-(3-thienyl)acrylonitrile
CAS 1164503-74-5C13H10N2S
3-(4-Methoxyanilino)-2-(3-thienyl)acrylonitrile chemical structure, C14H12N2OS, CAS 477850-91-2
3-(4-Methoxyanilino)-2-(3-thienyl)acrylonitrile
CAS 477850-91-2C14H12N2OS
2-(3-Thienyl)-3-(4-toluidino)acrylonitrile chemical structure, C14H12N2S, CAS 1164478-97-0
2-(3-Thienyl)-3-(4-toluidino)acrylonitrile
CAS 1164478-97-0C14H12N2S
3-(3,4-Dimethylanilino)-2-(3-thienyl)acrylonitrile chemical structure, C15H14N2S, CAS 1164503-62-1
3-(3,4-Dimethylanilino)-2-(3-thienyl)acrylonitrile
CAS 1164503-62-1C15H14N2S
(E)-3-(2,4-Dimethoxyanilino)-2-thiophen-3-ylprop-2-enenitrile chemical structure, C15H14N2O2S, CAS 477851-19-7
(E)-3-(2,4-Dimethoxyanilino)-2-thiophen-3-ylprop-2-enenitrile
CAS 477851-19-7C15H14N2O2S
3-[3-(Methylsulfanyl)anilino]-2-(3-thienyl)acrylonitrile chemical structure, C14H12N2S2, CAS 477851-20-0
3-[3-(Methylsulfanyl)anilino]-2-(3-thienyl)acrylonitrile
CAS 477851-20-0C14H12N2S2
(E)-3-(4-Chloroanilino)-2-thiophen-3-ylprop-2-enenitrile chemical structure, C13H9ClN2S, CAS 477851-21-1
(E)-3-(4-Chloroanilino)-2-thiophen-3-ylprop-2-enenitrile
CAS 477851-21-1C13H9ClN2S
(E)-3-(2,4-Dichloroanilino)-2-thiophen-3-ylprop-2-enenitrile chemical structure, C13H8Cl2N2S, CAS 477851-23-3
(E)-3-(2,4-Dichloroanilino)-2-thiophen-3-ylprop-2-enenitrile
CAS 477851-23-3C13H8Cl2N2S
4-{[2-Cyano-2-(3-thienyl)vinyl]amino}benzenecarboxylic acid chemical structure, C14H10N2O2S, CAS 477851-25-5
4-{[2-Cyano-2-(3-thienyl)vinyl]amino}benzenecarboxylic acid
CAS 477851-25-5C14H10N2O2S
Methyl 4-{[2-cyano-2-(3-thienyl)vinyl]amino}benzenecarboxylate chemical structure, C15H12N2O2S, CAS 477851-26-6
Methyl 4-{[2-cyano-2-(3-thienyl)vinyl]amino}benzenecarboxylate
CAS 477851-26-6C15H12N2O2S
3-{[3-(Methylsulfanyl)phenyl]amino}-2-(thiophen-3-yl)prop-2-enenitrile chemical structure, C14H12N2S2
3-{[3-(Methylsulfanyl)phenyl]amino}-2-(thiophen-3-yl)prop-2-enenitrile
C14H12N2S2
3-[(2,4-Dichlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile chemical structure, C13H8Cl2N2S
3-[(2,4-Dichlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile
C13H8Cl2N2S