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Murcko scaffold

2-(1H-Indol-3-yl)-2-oxo-N-phenylacetamide scaffold

231 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
231
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)C(=O)c1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Indol-3-yl)-2-oxo-N-phenylacetamide page
Murcko scaffold O=C(Nc1ccccc1)C(=O)c1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 231 chemicals

N-(4-Bromophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H11BrN2O2, CAS 339111-11-4
N-(4-Bromophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 339111-11-4C16H11BrN2O2
4-[2-(1H-Indol-3-yl)-2-oxo-acetylamino]-benzoic acid methyl ester chemical structure, C18H14N2O4, CAS 620100-69-8
4-[2-(1H-Indol-3-yl)-2-oxo-acetylamino]-benzoic acid methyl ester
CAS 620100-69-8C18H14N2O4
N-(2,6-Dimethylphenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C19H18N2O2, CAS 696638-35-4
N-(2,6-Dimethylphenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 696638-35-4C19H18N2O2
2-(1H-Indol-3-yl)-2-oxo-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C17H11F3N2O2, CAS 633282-69-6
2-(1H-Indol-3-yl)-2-oxo-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 633282-69-6C17H11F3N2O2
N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H10BrFN2O2, CAS 256458-69-2
N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide
CAS 256458-69-2C16H10BrFN2O2
N-(2-Fluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H11FN2O2, CAS 852367-64-7
N-(2-Fluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 852367-64-7C16H11FN2O2
N-(2-Methoxyphenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H16N2O3, CAS 838874-39-8
N-(2-Methoxyphenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 838874-39-8C18H16N2O3
N-(4-Fluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H11FN2O2, CAS 204206-06-4
N-(4-Fluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 204206-06-4C16H11FN2O2
N-(2-Fluorophenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C17H13FN2O2, CAS 838889-81-9
N-(2-Fluorophenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 838889-81-9C17H13FN2O2
N-(3-Methoxyphenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H16N2O3, CAS 852369-23-4
N-(3-Methoxyphenyl)-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 852369-23-4C18H16N2O3
N-(2,3-Dimethylphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H16N2O2, CAS 852367-77-2
N-(2,3-Dimethylphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 852367-77-2C18H16N2O2
2-(2-Methyl-1H-indol-3-yl)-2-oxo-N-phenylacetamide chemical structure, C17H14N2O2, CAS 93323-60-5
2-(2-Methyl-1H-indol-3-yl)-2-oxo-N-phenylacetamide
CAS 93323-60-5C17H14N2O2
2-(1H-Indol-3-yl)-N-(2-methoxyphenyl)-2-oxoacetamide chemical structure, C17H14N2O3, CAS 620100-74-5
2-(1H-Indol-3-yl)-N-(2-methoxyphenyl)-2-oxoacetamide
CAS 620100-74-5C17H14N2O3
2-(1H-Indol-3-yl)-2-oxo-N-phenylacetamide chemical structure, C16H12N2O2, CAS 73031-16-0
2-(1H-Indol-3-yl)-2-oxo-N-phenylacetamide
CAS 73031-16-0C16H12N2O2
2-(1H-Indol-3-yl)-2-oxo-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C17H11F3N2O3, CAS 852367-70-5
2-(1H-Indol-3-yl)-2-oxo-N-[4-(trifluoromethoxy)phenyl]acetamide
CAS 852367-70-5C17H11F3N2O3
N-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H10F2N2O2, CAS 946387-17-3
N-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 946387-17-3C16H10F2N2O2
N-(2-Ethylphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H16N2O2, CAS 312922-91-1
N-(2-Ethylphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 312922-91-1C18H16N2O2
N-(4-Ethoxyphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H16N2O3, CAS 313375-95-0
N-(4-Ethoxyphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 313375-95-0C18H16N2O3
2-(1H-Indol-3-yl)-N-[3-methyl-4-(propan-2-yl)phenyl]-2-oxoacetamide chemical structure, C20H20N2O2, CAS 946387-20-8
2-(1H-Indol-3-yl)-N-[3-methyl-4-(propan-2-yl)phenyl]-2-oxoacetamide
CAS 946387-20-8C20H20N2O2
2-(1H-Indol-3-yl)-2-oxo-N-[3-(trifluoromethoxy)phenyl]acetamide chemical structure, C17H11F3N2O3, CAS 1023559-26-3
2-(1H-Indol-3-yl)-2-oxo-N-[3-(trifluoromethoxy)phenyl]acetamide
CAS 1023559-26-3C17H11F3N2O3
N-(4-Fluorophenyl)-2-(2-hydroxy-5-nitro-1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H10FN3O5, CAS 380426-99-3
N-(4-Fluorophenyl)-2-(2-hydroxy-5-nitro-1H-indol-3-yl)-2-oxoacetamide
CAS 380426-99-3C16H10FN3O5
N-(3,4-Dimethoxyphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C18H16N2O4, CAS 852367-82-9
N-(3,4-Dimethoxyphenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 852367-82-9C18H16N2O4
N-(4-Chloro-3-nitrophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C16H10ClN3O4, CAS 1024255-49-9
N-(4-Chloro-3-nitrophenyl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 1024255-49-9C16H10ClN3O4
2-(1H-Indol-3-yl)-2-oxo-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]acetamide chemical structure, C18H12F4N2O3, CAS 1024338-95-1
2-(1H-Indol-3-yl)-2-oxo-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]acetamide
CAS 1024338-95-1C18H12F4N2O3