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Murcko scaffold

Ring system with 2 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(COC(=O)Cc1ccccc1)NC1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)Cc1ccccc1)NC1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

(Cyclopentylcarbamoyl)methyl 2-(4-chlorophenyl)acetate chemical structure, C15H18ClNO3, CAS 479042-98-3
(Cyclopentylcarbamoyl)methyl 2-(4-chlorophenyl)acetate
CAS 479042-98-3C15H18ClNO3
[1-(Cyclopentylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)acetate chemical structure, C16H20BrNO3, CAS 852682-58-7
[1-(Cyclopentylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)acetate
CAS 852682-58-7C16H20BrNO3
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(3,4-dichlorophenyl)acetate chemical structure, C16H16Cl2N2O3, CAS 1003765-38-5
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(3,4-dichlorophenyl)acetate
CAS 1003765-38-5C16H16Cl2N2O3
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(3,4-dimethoxyphenyl)acetate chemical structure, C18H22N2O5, CAS 931625-38-6
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(3,4-dimethoxyphenyl)acetate
CAS 931625-38-6C18H22N2O5
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(2-fluorophenyl)acetate chemical structure, C16H17FN2O3, CAS 1001901-35-4
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(2-fluorophenyl)acetate
CAS 1001901-35-4C16H17FN2O3
[2-[(1-Cyanocyclopentyl)amino]-2-oxoethyl] 2-(3-methoxyphenyl)acetate chemical structure, C17H20N2O4, CAS 1002473-46-2
[2-[(1-Cyanocyclopentyl)amino]-2-oxoethyl] 2-(3-methoxyphenyl)acetate
CAS 1002473-46-2C17H20N2O4
[2-(Cyclopentylamino)-2-oxoethyl] 2-(2-methoxyphenyl)acetate chemical structure, C16H21NO4, CAS 1794982-00-5
[2-(Cyclopentylamino)-2-oxoethyl] 2-(2-methoxyphenyl)acetate
CAS 1794982-00-5C16H21NO4
2-(Cyclopentylamino)-2-oxoethyl (4-methylphenyl)acetate chemical structure, C16H21NO3, CAS 1638737-54-8
2-(Cyclopentylamino)-2-oxoethyl (4-methylphenyl)acetate
CAS 1638737-54-8C16H21NO3
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(2-bromo-4,5-dimethoxyphenyl)acetate chemical structure, C18H21BrN2O5, CAS 871495-80-6
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(2-bromo-4,5-dimethoxyphenyl)acetate
CAS 871495-80-6C18H21BrN2O5
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(2-bromo-4,5-diethoxyphenyl)acetate chemical structure, C20H25BrN2O5, CAS 1356680-83-5
[(1-Cyanocyclopentyl)carbamoyl]methyl 2-(2-bromo-4,5-diethoxyphenyl)acetate
CAS 1356680-83-5C20H25BrN2O5
[2-[(1-Cyanocyclopentyl)amino]-2-oxoethyl] 2-[4-(difluoromethoxy)phenyl]acetate chemical structure, C17H18F2N2O4, CAS 1365625-13-3
[2-[(1-Cyanocyclopentyl)amino]-2-oxoethyl] 2-[4-(difluoromethoxy)phenyl]acetate
CAS 1365625-13-3C17H18F2N2O4
(Cyclopentylcarbamoyl)methyl 2-(4-ethoxyphenyl)acetate chemical structure, C17H23NO4, CAS 1324746-33-9
(Cyclopentylcarbamoyl)methyl 2-(4-ethoxyphenyl)acetate
CAS 1324746-33-9C17H23NO4