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Murcko scaffold

Ring system with 3 rings and 22 atoms

266 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
266
With full pages
13
Scaffold SMILES

O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 266 chemicals

N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxy-N-(2-ethylphenyl)benzamide chemical structure, C21H23NO4S, CAS 863444-06-8
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxy-N-(2-ethylphenyl)benzamide
CAS 863444-06-8C21H23NO4S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-3,4-dimethylbenzamide chemical structure, C21H23NO3S, CAS 863444-10-4
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-3,4-dimethylbenzamide
CAS 863444-10-4C21H23NO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-3,4-dimethoxybenzamide chemical structure, C21H23NO5S, CAS 863444-12-6
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-3,4-dimethoxybenzamide
CAS 863444-12-6C21H23NO5S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-3,4,5-trimethoxybenzamide chemical structure, C22H25NO6S, CAS 863444-13-7
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-3,4,5-trimethoxybenzamide
CAS 863444-13-7C22H25NO6S
4-(N,N-Dimethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-isopropylphenyl)benzamide chemical structure, C22H26N2O5S2, CAS 863445-22-1
4-(N,N-Dimethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-isopropylphenyl)benzamide
CAS 863445-22-1C22H26N2O5S2
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-diethoxybenzamide chemical structure, C21H22BrNO5S, CAS 863445-48-1
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-diethoxybenzamide
CAS 863445-48-1C21H22BrNO5S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methylbenzamide chemical structure, C18H16BrNO3S, CAS 863445-58-3
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methylbenzamide
CAS 863445-58-3C18H16BrNO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-dimethoxybenzamide chemical structure, C19H18BrNO5S, CAS 863445-66-3
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-dimethoxybenzamide
CAS 863445-66-3C19H18BrNO5S
N-(4-Bromophenyl)-4-(N,N-dimethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C19H19BrN2O5S2, CAS 863445-68-5
N-(4-Bromophenyl)-4-(N,N-dimethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide
CAS 863445-68-5C19H19BrN2O5S2
N-(3,5-Dimethylphenyl)-4-(N,N-dimethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C21H24N2O5S2, CAS 863446-16-6
N-(3,5-Dimethylphenyl)-4-(N,N-dimethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide
CAS 863446-16-6C21H24N2O5S2
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2,4-dimethoxybenzamide chemical structure, C21H23NO5S, CAS 863446-21-3
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2,4-dimethoxybenzamide
CAS 863446-21-3C21H23NO5S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-fluorophenyl)benzamide chemical structure, C17H14FNO3S, CAS 852438-90-5
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-fluorophenyl)benzamide
CAS 852438-90-5C17H14FNO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-methoxy-N-(p-tolyl)benzamide chemical structure, C19H19NO4S, CAS 449782-88-1
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-methoxy-N-(p-tolyl)benzamide
CAS 449782-88-1C19H19NO4S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3-methyl-N-(p-tolyl)benzamide chemical structure, C19H19NO3S, CAS 852438-31-4
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3-methyl-N-(p-tolyl)benzamide
CAS 852438-31-4C19H19NO3S
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-N-(4-ethoxyphenyl)-4-methoxybenzamide chemical structure, C20H21NO5S, CAS 863020-98-8
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-N-(4-ethoxyphenyl)-4-methoxybenzamide
CAS 863020-98-8C20H21NO5S
N-(3,4-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methoxybenzamide chemical structure, C20H21NO4S, CAS 863021-85-6
N-(3,4-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methoxybenzamide
CAS 863021-85-6C20H21NO4S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methoxybenzamide chemical structure, C19H18ClNO4S, CAS 863008-11-1
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methoxybenzamide
CAS 863008-11-1C19H18ClNO4S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methoxybenzamide chemical structure, C18H16BrNO4S, CAS 852439-88-4
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-methoxybenzamide
CAS 852439-88-4C18H16BrNO4S
N-(4-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-4-methoxybenzamide chemical structure, C18H16ClNO4S, CAS 863007-33-4
N-(4-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-4-methoxybenzamide
CAS 863007-33-4C18H16ClNO4S
N-(3-Chlorophenyl)-N-(1,1-dioxo-2,3-dihydro-1lambda6-thiophen-3-yl)benzamide chemical structure, C17H14ClNO3S, CAS 321977-89-3
N-(3-Chlorophenyl)-N-(1,1-dioxo-2,3-dihydro-1lambda6-thiophen-3-yl)benzamide
CAS 321977-89-3C17H14ClNO3S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-fluorobenzamide chemical structure, C18H15ClFNO3S, CAS 321978-03-4
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-fluorobenzamide
CAS 321978-03-4C18H15ClFNO3S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-fluorobenzamide chemical structure, C18H15ClFNO3S, CAS 321978-04-5
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-fluorobenzamide
CAS 321978-04-5C18H15ClFNO3S
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-N-(2-ethylphenyl)benzamide chemical structure, C19H19NO3S, CAS 326016-76-6
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-N-(2-ethylphenyl)benzamide
CAS 326016-76-6C19H19NO3S
N-(4-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3,5-dimethylbenzamide chemical structure, C19H18ClNO3S, CAS 863007-15-2
N-(4-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3,5-dimethylbenzamide
CAS 863007-15-2C19H18ClNO3S