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Murcko scaffold

Ring system with 3 rings and 22 atoms

266 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
266
With full pages
0
Scaffold SMILES

O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 266 of 266 chemicals

4-(tert-Butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-isopropylphenyl)benzamide chemical structure, C24H29NO3S, CAS 852439-71-5
4-(tert-Butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-isopropylphenyl)benzamide
CAS 852439-71-5C24H29NO3S
4-(N,N-Diethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-isopropylphenyl)benzamide chemical structure, C24H30N2O5S2, CAS 852439-75-9
4-(N,N-Diethylsulfamoyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-isopropylphenyl)benzamide
CAS 852439-75-9C24H30N2O5S2
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethylbenzamide chemical structure, C19H18BrNO3S, CAS 863445-32-3
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethylbenzamide
CAS 863445-32-3C19H18BrNO3S
2-Bromo-N-(4-bromophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)benzamide chemical structure, C17H13Br2NO3S, CAS 852439-82-8
2-Bromo-N-(4-bromophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)benzamide
CAS 852439-82-8C17H13Br2NO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-fluorobenzamide chemical structure, C17H13BrFNO3S, CAS 863445-59-4
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-fluorobenzamide
CAS 863445-59-4C17H13BrFNO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-fluorobenzamide chemical structure, C17H13BrFNO3S, CAS 863445-60-7
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-fluorobenzamide
CAS 863445-60-7C17H13BrFNO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methoxybenzamide chemical structure, C18H16BrNO4S, CAS 852439-86-2
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methoxybenzamide
CAS 852439-86-2C18H16BrNO4S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-methoxybenzamide chemical structure, C18H16BrNO4S, CAS 852439-87-3
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-methoxybenzamide
CAS 852439-87-3C18H16BrNO4S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxybenzamide chemical structure, C19H18BrNO4S, CAS 863445-61-8
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxybenzamide
CAS 863445-61-8C19H18BrNO4S
N-(4-Bromophenyl)-4-butoxy-N-(1,1-dioxo-2,3-dihydro-1lambda6-thiophen-3-yl)benzamide chemical structure, C21H22BrNO4S, CAS 852439-89-5
N-(4-Bromophenyl)-4-butoxy-N-(1,1-dioxo-2,3-dihydro-1lambda6-thiophen-3-yl)benzamide
CAS 852439-89-5C21H22BrNO4S
N-(4-Bromophenyl)-4-(tert-butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C21H22BrNO3S, CAS 863445-62-9
N-(4-Bromophenyl)-4-(tert-butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide
CAS 863445-62-9C21H22BrNO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-(trifluoromethyl)benzamide chemical structure, C18H13BrF3NO3S, CAS 852439-90-8
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-(trifluoromethyl)benzamide
CAS 852439-90-8C18H13BrF3NO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-dimethylbenzamide chemical structure, C19H18BrNO3S, CAS 863445-64-1
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-dimethylbenzamide
CAS 863445-64-1C19H18BrNO3S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4,5-trimethoxybenzamide chemical structure, C20H20BrNO6S, CAS 863445-67-4
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4,5-trimethoxybenzamide
CAS 863445-67-4C20H20BrNO6S
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methylbenzamide chemical structure, C20H21NO3S, CAS 863445-93-6
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methylbenzamide
CAS 863445-93-6C20H21NO3S
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3-methylbenzamide chemical structure, C20H21NO3S, CAS 863445-94-7
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3-methylbenzamide
CAS 863445-94-7C20H21NO3S
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-4-methylbenzamide chemical structure, C20H21NO3S, CAS 863445-95-8
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-4-methylbenzamide
CAS 863445-95-8C20H21NO3S
3-Chloro-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)benzamide chemical structure, C19H18ClNO3S, CAS 863445-96-9
3-Chloro-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)benzamide
CAS 863445-96-9C19H18ClNO3S
4-Chloro-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)benzamide chemical structure, C19H18ClNO3S, CAS 863445-97-0
4-Chloro-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)benzamide
CAS 863445-97-0C19H18ClNO3S
2-Bromo-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydro-3-thiophenyl)benzamide chemical structure, C19H18BrNO3S, CAS 863445-98-1
2-Bromo-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydro-3-thiophenyl)benzamide
CAS 863445-98-1C19H18BrNO3S
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-fluorobenzamide chemical structure, C19H18FNO3S, CAS 863446-02-0
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-fluorobenzamide
CAS 863446-02-0C19H18FNO3S
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydro-3-thiophenyl)-3-methoxybenzamide chemical structure, C20H21NO4S, CAS 863446-04-2
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydro-3-thiophenyl)-3-methoxybenzamide
CAS 863446-04-2C20H21NO4S
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxybenzamide chemical structure, C21H23NO4S, CAS 863446-06-4
N-(3,5-Dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxybenzamide
CAS 863446-06-4C21H23NO4S
4-(tert-Butyl)-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C23H27NO3S, CAS 863446-08-6
4-(tert-Butyl)-N-(3,5-dimethylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide
CAS 863446-08-6C23H27NO3S