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Murcko scaffold

Ring system with 3 rings and 22 atoms

266 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
266
With full pages
13
Scaffold SMILES

O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 266 chemicals

N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-dimethylbenzamide chemical structure, C19H18ClNO3S, CAS 863007-73-2
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4-dimethylbenzamide
CAS 863007-73-2C19H18ClNO3S
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3,5-dimethoxybenzamide chemical structure, C19H18ClNO5S, CAS 863007-74-3
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3,5-dimethoxybenzamide
CAS 863007-74-3C19H18ClNO5S
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-2,3-dimethoxybenzamide chemical structure, C19H18ClNO5S, CAS 863007-75-4
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-2,3-dimethoxybenzamide
CAS 863007-75-4C19H18ClNO5S
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3,4-dimethoxybenzamide chemical structure, C19H18ClNO5S, CAS 863007-76-5
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3,4-dimethoxybenzamide
CAS 863007-76-5C19H18ClNO5S
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4,5-trimethoxybenzamide chemical structure, C20H20ClNO6S, CAS 863007-77-6
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4,5-trimethoxybenzamide
CAS 863007-77-6C20H20ClNO6S
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4,5-triethoxybenzamide chemical structure, C23H26ClNO6S, CAS 863007-78-7
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,4,5-triethoxybenzamide
CAS 863007-78-7C23H26ClNO6S
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-isopropoxybenzamide chemical structure, C20H20ClNO4S, CAS 863007-82-3
N-(3-Chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-4-isopropoxybenzamide
CAS 863007-82-3C20H20ClNO4S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethylbenzamide chemical structure, C20H20ClNO3S, CAS 863007-88-9
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethylbenzamide
CAS 863007-88-9C20H20ClNO3S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methoxybenzamide chemical structure, C19H18ClNO4S, CAS 863008-09-7
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2-methoxybenzamide
CAS 863008-09-7C19H18ClNO4S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-methoxybenzamide chemical structure, C19H18ClNO4S, CAS 863008-10-0
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-methoxybenzamide
CAS 863008-10-0C19H18ClNO4S
4-(tert-Butyl)-N-(3-chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C22H24ClNO3S, CAS 863008-14-4
4-(tert-Butyl)-N-(3-chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide
CAS 863008-14-4C22H24ClNO3S
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2,6-difluorobenzamide chemical structure, C18H14ClF2NO3S, CAS 863008-16-6
N-(3-Chloro-4-methylphenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-2,6-difluorobenzamide
CAS 863008-16-6C18H14ClF2NO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethyl-N-(p-tolyl)benzamide chemical structure, C20H21NO3S, CAS 863008-29-1
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethyl-N-(p-tolyl)benzamide
CAS 863008-29-1C20H21NO3S
N-(1,1-Dioxo-2,3-dihydro-1lambda6-thiophen-3-yl)-3,4-diethoxy-N-(4-methylphenyl)benzamide chemical structure, C22H25NO5S, CAS 852438-27-8
N-(1,1-Dioxo-2,3-dihydro-1lambda6-thiophen-3-yl)-3,4-diethoxy-N-(4-methylphenyl)benzamide
CAS 852438-27-8C22H25NO5S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-2-methyl-N-(p-tolyl)benzamide chemical structure, C19H19NO3S, CAS 863020-59-1
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-2-methyl-N-(p-tolyl)benzamide
CAS 863020-59-1C19H19NO3S
2-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide chemical structure, C18H16ClNO3S, CAS 863020-60-4
2-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide
CAS 863020-60-4C18H16ClNO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-2-fluoro-N-(p-tolyl)benzamide chemical structure, C18H16FNO3S, CAS 863020-61-5
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-2-fluoro-N-(p-tolyl)benzamide
CAS 863020-61-5C18H16FNO3S
4-Butoxy-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide chemical structure, C22H25NO4S, CAS 852438-35-8
4-Butoxy-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide
CAS 852438-35-8C22H25NO4S
2-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-6-fluoro-N-(p-tolyl)benzamide chemical structure, C18H15ClFNO3S, CAS 852438-38-1
2-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-6-fluoro-N-(p-tolyl)benzamide
CAS 852438-38-1C18H15ClFNO3S
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-3,4-dimethyl-N-(4-methylphenyl)benzamide chemical structure, C20H21NO3S, CAS 852438-39-2
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-3,4-dimethyl-N-(4-methylphenyl)benzamide
CAS 852438-39-2C20H21NO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethoxy-N-(p-tolyl)benzamide chemical structure, C20H21NO5S, CAS 863020-64-8
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3,5-dimethoxy-N-(p-tolyl)benzamide
CAS 863020-64-8C20H21NO5S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-isopropoxy-N-(p-tolyl)benzamide chemical structure, C21H23NO4S, CAS 852438-40-5
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-isopropoxy-N-(p-tolyl)benzamide
CAS 852438-40-5C21H23NO4S
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-N-(4-ethoxyphenyl)-3,5-dimethylbenzamide chemical structure, C21H23NO4S, CAS 852438-41-6
N-(1,1-Dioxido-2,3-dihydrothien-3-yl)-N-(4-ethoxyphenyl)-3,5-dimethylbenzamide
CAS 852438-41-6C21H23NO4S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)-2-methylbenzamide chemical structure, C20H21NO4S, CAS 863020-91-1
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)-2-methylbenzamide
CAS 863020-91-1C20H21NO4S