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Murcko scaffold

2,3-Dihydroisoquinolin-4(1H)-one scaffold

62 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
62
With full pages
0
Scaffold SMILES

O=C1CNCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Dihydroisoquinolin-4(1H)-one page
Murcko scaffold O=C1CNCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

2-Methyl-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C10H11NO, CAS 79841-13-7
2-Methyl-2,3-dihydroisoquinolin-4(1H)-one
CAS 79841-13-7C10H11NO
4(1H)-Isoquinolinone,2,3-dihydro-5,6-dihydroxy-7-methoxy-2-methyl- chemical structure, C11H13NO4, CAS 751424-21-2
4(1H)-Isoquinolinone,2,3-dihydro-5,6-dihydroxy-7-methoxy-2-methyl-
CAS 751424-21-2C11H13NO4
2-Ethyl-1,2,3,4-tetrahydroisoquinolin-4-one chemical structure, C11H13NO, CAS 78175-86-7
2-Ethyl-1,2,3,4-tetrahydroisoquinolin-4-one
CAS 78175-86-7C11H13NO
7-(Methylthio)-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C10H11NOS, CAS 90265-84-2
7-(Methylthio)-2,3-dihydroisoquinolin-4(1H)-one
CAS 90265-84-2C10H11NOS
2-Acetyl-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C11H11NO2, CAS 105121-99-1
2-Acetyl-2,3-dihydroisoquinolin-4(1H)-one
CAS 105121-99-1C11H11NO2
7-Methoxy-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C10H11NO2, CAS 67902-64-1
7-Methoxy-2,3-dihydroisoquinolin-4(1H)-one
CAS 67902-64-1C10H11NO2
5-Chloro-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C9H8ClNO, CAS 89097-92-7
5-Chloro-2,3-dihydroisoquinolin-4(1H)-one
CAS 89097-92-7C9H8ClNO
7-Chloro-2,3-dihydro-2-methyl-4(1H)-isoquinolinone chemical structure, C10H10ClNO, CAS 321330-39-6
7-Chloro-2,3-dihydro-2-methyl-4(1H)-isoquinolinone
CAS 321330-39-6C10H10ClNO
Ethyl 1,2,3,4-tetrahydro-2-methyl-4-oxo-3-isoquinolinecarboxylate chemical structure, C13H15NO3, CAS 100372-65-4
Ethyl 1,2,3,4-tetrahydro-2-methyl-4-oxo-3-isoquinolinecarboxylate
CAS 100372-65-4C13H15NO3
2,3-Dihydroisoquinolin-4(1H)-one chemical structure, C9H9NO, CAS 51641-22-6
2,3-Dihydroisoquinolin-4(1H)-one
CAS 51641-22-6C9H9NO
tert-Butyl 4-oxo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate chemical structure, C14H17NO3, CAS 1134327-89-1
tert-Butyl 4-oxo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
CAS 1134327-89-1C14H17NO3
7-Methoxy-2,3-dihydroisoquinolin-4(1H)-one--hydrogen chloride (1/1) chemical structure, C10H12ClNO2, CAS 5119-79-9
7-Methoxy-2,3-dihydroisoquinolin-4(1H)-one--hydrogen chloride (1/1)
CAS 5119-79-9C10H12ClNO2
2-Methanesulfonyl-2,3-dihydro-1H-isoquinolin-4-one chemical structure, C10H11NO3S, CAS 1235981-58-4
2-Methanesulfonyl-2,3-dihydro-1H-isoquinolin-4-one
CAS 1235981-58-4C10H11NO3S
7-Bromo-2,3-dihydro-1H-isoquinolin-4-one chemical structure, C9H8BrNO, CAS 1056191-37-7
7-Bromo-2,3-dihydro-1H-isoquinolin-4-one
CAS 1056191-37-7C9H8BrNO
7-Chloro-2,3-dihydro-4(1H)-isoquinolinone chemical structure, C9H8ClNO, CAS 749196-13-2
7-Chloro-2,3-dihydro-4(1H)-isoquinolinone
CAS 749196-13-2C9H8ClNO
7-Methoxy-1,1-dimethyl-2,3-dihydroisoquinolin-4-one chemical structure, C12H15NO2, CAS 1022948-18-0
7-Methoxy-1,1-dimethyl-2,3-dihydroisoquinolin-4-one
CAS 1022948-18-0C12H15NO2
Methyl 4-oxo-1,2,3,4-tetrahydroisoquinoline-1-carboxylate chemical structure, C11H11NO3, CAS 478623-80-2
Methyl 4-oxo-1,2,3,4-tetrahydroisoquinoline-1-carboxylate
CAS 478623-80-2C11H11NO3
4-Oxo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid chemical structure, C10H9NO3, CAS 1515592-67-2
4-Oxo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
CAS 1515592-67-2C10H9NO3
6-Chloro-2-propanoyl-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C12H12ClNO2, CAS 89097-74-5
6-Chloro-2-propanoyl-2,3-dihydroisoquinolin-4(1H)-one
CAS 89097-74-5C12H12ClNO2
7-Fluoro-2,3-dihydroisoquinolin-4(1H)-one chemical structure, C9H8FNO, CAS 89097-90-5
7-Fluoro-2,3-dihydroisoquinolin-4(1H)-one
CAS 89097-90-5C9H8FNO
2-Propyl-1,3-dihydroisoquinolin-4-one, hydrochloride chemical structure, C12H16ClNO, CAS 144479-94-7
2-Propyl-1,3-dihydroisoquinolin-4-one, hydrochloride
CAS 144479-94-7C12H16ClNO
5-(Methylsulfanyl)-2,3-dihydroisoquinolin-4(1H)-one--hydrogen chloride (1/1) chemical structure, C10H12ClNOS, CAS 90265-85-3
5-(Methylsulfanyl)-2,3-dihydroisoquinolin-4(1H)-one--hydrogen chloride (1/1)
CAS 90265-85-3C10H12ClNOS
2,3-Dihydroisoquinolin-4(1H)-one hydrochloride chemical structure, C9H10ClNO, CAS 1196157-36-4
2,3-Dihydroisoquinolin-4(1H)-one hydrochloride
CAS 1196157-36-4C9H10ClNO
6-Chloro-2,3-dihydro-1H-isoquinolin-4-one hydrochloride chemical structure, C9H9Cl2NO, CAS 1414958-16-9
6-Chloro-2,3-dihydro-1H-isoquinolin-4-one hydrochloride
CAS 1414958-16-9C9H9Cl2NO