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Murcko scaffold

Ring system with 2 rings and 10 atoms

50 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
50
With full pages
10
Scaffold SMILES

c1cc(-c2cscn2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(-c2cscn2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 50 chemicals

4-(2,5-Dimethyl-1-propyl-3-pyrrolyl)-2-thiazolamine chemical structure, C12H17N3S, CAS 900640-62-2
4-(2,5-Dimethyl-1-propyl-3-pyrrolyl)-2-thiazolamine
CAS 900640-62-2C12H17N3S
4-[2,5-Dimethyl-1-(prop-2-en-1-yl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine chemical structure, C12H15N3S, CAS 900641-39-6
4-[2,5-Dimethyl-1-(prop-2-en-1-yl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine
CAS 900641-39-6C12H15N3S
4-(2,5-Dimethyl-1-prop-2-enylpyrrol-3-yl)-N-methyl-1,3-thiazol-2-amine chemical structure, C13H17N3S, CAS 851623-75-1
4-(2,5-Dimethyl-1-prop-2-enylpyrrol-3-yl)-N-methyl-1,3-thiazol-2-amine
CAS 851623-75-1C13H17N3S
4-[2,5-Dimethyl-1-(3-methylbutyl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine chemical structure, C14H21N3S, CAS 900641-43-2
4-[2,5-Dimethyl-1-(3-methylbutyl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine
CAS 900641-43-2C14H21N3S
4-(1,2,5-Trimethyl-1H-pyrrol-3-yl)thiazol-2-amine chemical structure, C10H13N3S, CAS 793727-92-1
4-(1,2,5-Trimethyl-1H-pyrrol-3-yl)thiazol-2-amine
CAS 793727-92-1C10H13N3S
4-[1-(2-Methoxy-ethyl)-2,5-dimethyl-1H-pyrrol-3-yl]-thiazol-2-ylamine chemical structure, C12H17N3OS, CAS 917748-66-4
4-[1-(2-Methoxy-ethyl)-2,5-dimethyl-1H-pyrrol-3-yl]-thiazol-2-ylamine
CAS 917748-66-4C12H17N3OS
2-(4-(1-Methyl-5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl)thiazol-2-yl)acetonitrile chemical structure, C12H8Cl3N3OS, CAS 791771-79-4
2-(4-(1-Methyl-5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl)thiazol-2-yl)acetonitrile
CAS 791771-79-4C12H8Cl3N3OS
4-(1-Ethyl-2,5-dimethyl-1H-pyrrol-3-yl)-thiazol-2-ylamine chemical structure, C11H15N3S, CAS 887694-90-8
4-(1-Ethyl-2,5-dimethyl-1H-pyrrol-3-yl)-thiazol-2-ylamine
CAS 887694-90-8C11H15N3S
4-(1-Isopropyl-2,5-dimethyl-1H-pyrrol-3-yl)-thiazol-2-ylamine chemical structure, C12H17N3S, CAS 887694-93-1
4-(1-Isopropyl-2,5-dimethyl-1H-pyrrol-3-yl)-thiazol-2-ylamine
CAS 887694-93-1C12H17N3S
2-[3-(2-Amino-thiazol-4-yl)-2,5-dimethyl-pyrrol-1-yl]-ethanol chemical structure, C11H15N3OS, CAS 883545-62-8
2-[3-(2-Amino-thiazol-4-yl)-2,5-dimethyl-pyrrol-1-yl]-ethanol
CAS 883545-62-8C11H15N3OS
4-(2-Methyl-1,3-thiazol-4-yl)-1H-pyrrole-2-carboxylic acid chemical structure, C9H8N2O2S, CAS 871547-64-7
4-(2-Methyl-1,3-thiazol-4-yl)-1H-pyrrole-2-carboxylic acid
CAS 871547-64-7C9H8N2O2S
4-(2,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrrol-3-yl)thiazol-2-amine chemical structure, C11H12F3N3S, CAS 1333817-80-3
4-(2,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrrol-3-yl)thiazol-2-amine
CAS 1333817-80-3C11H12F3N3S
1-Methyl-4-(2-methyl-1,3-thiazol-4-yl)-1H-pyrrole-2-carboxylic acid chemical structure, C10H10N2O2S, CAS 877041-31-1
1-Methyl-4-(2-methyl-1,3-thiazol-4-yl)-1H-pyrrole-2-carboxylic acid
CAS 877041-31-1C10H10N2O2S
4-(2,5-Dimethyl-1-propyl-1H-pyrrol-3-yl)-N-(2-methoxyethyl)-1,3-thiazol-2-amine chemical structure, C15H23N3OS, CAS 1351527-35-9
4-(2,5-Dimethyl-1-propyl-1H-pyrrol-3-yl)-N-(2-methoxyethyl)-1,3-thiazol-2-amine
CAS 1351527-35-9C15H23N3OS
N-Methyl-4-(1,2,5-trimethyl-1H-pyrrol-3-yl)-1,3-thiazol-2-amine chemical structure, C11H15N3S, CAS 930447-23-7
N-Methyl-4-(1,2,5-trimethyl-1H-pyrrol-3-yl)-1,3-thiazol-2-amine
CAS 930447-23-7C11H15N3S
4-[2,5-Dimethyl-1-(3-methylbutyl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride chemical structure, C14H22ClN3S, CAS 1049742-14-4
4-[2,5-Dimethyl-1-(3-methylbutyl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride
CAS 1049742-14-4C14H22ClN3S
4-(2,5-Dimethyl-1-propyl-1H-pyrrol-3-yl)-1,3-thiazol-2-amine hydrochloride chemical structure, C12H18ClN3S, CAS 1049732-72-0
4-(2,5-Dimethyl-1-propyl-1H-pyrrol-3-yl)-1,3-thiazol-2-amine hydrochloride
CAS 1049732-72-0C12H18ClN3S
4-[2,5-Dimethyl-1-(prop-2-en-1-yl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride chemical structure, C12H16ClN3S, CAS 1049717-89-6
4-[2,5-Dimethyl-1-(prop-2-en-1-yl)-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride
CAS 1049717-89-6C12H16ClN3S
4-(1H-Pyrrol-3-yl)thiazol-2-amine chemical structure, C7H7N3S, CAS 189011-17-4
4-(1H-Pyrrol-3-yl)thiazol-2-amine
CAS 189011-17-4C7H7N3S
2-[4-(3-Pyrrolidinyl)1,3-thiazol-2yl]guanidine chemical structure, C8H9N5S, CAS 115027-94-6
2-[4-(3-Pyrrolidinyl)1,3-thiazol-2yl]guanidine
CAS 115027-94-6C8H9N5S
3-[2,5-Dimethyl-3-(2-methyl-1,3-thiazol-4-yl)-1H-pyrrol-1-yl]propanoic acid chemical structure, C13H16N2O2S, CAS 929975-25-7
3-[2,5-Dimethyl-3-(2-methyl-1,3-thiazol-4-yl)-1H-pyrrol-1-yl]propanoic acid
CAS 929975-25-7C13H16N2O2S
2-[2,5-Dimethyl-3-(2-methyl-1,3-thiazol-4-yl)-1H-pyrrol-1-yl]acetic acid chemical structure, C12H14N2O2S, CAS 929975-47-3
2-[2,5-Dimethyl-3-(2-methyl-1,3-thiazol-4-yl)-1H-pyrrol-1-yl]acetic acid
CAS 929975-47-3C12H14N2O2S
4-(2-Amino-1,3-thiazol-4-yl)-1H-pyrrole-2-carboxamide chemical structure, C8H8N4OS, CAS 929974-94-7
4-(2-Amino-1,3-thiazol-4-yl)-1H-pyrrole-2-carboxamide
CAS 929974-94-7C8H8N4OS
4-(2-Amino-4-thiazolyl)-1H-pyrrole-2-carboxylic acid chemical structure, C8H7N3O2S, CAS 929974-96-9
4-(2-Amino-4-thiazolyl)-1H-pyrrole-2-carboxylic acid
CAS 929974-96-9C8H7N3O2S