CompoundList
Sign in
Murcko scaffold

2-(1H-Pyrazol-3-yl)pyrazine scaffold

323 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
323
With full pages
4
Scaffold SMILES

c1cnc(-c2ccn[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-3-yl)pyrazine page
Murcko scaffold c1cnc(-c2ccn[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 323 chemicals

2-Methyl-3-(1H-pyrazol-5-yl)pyrazine chemical structure, C8H8N4, CAS 195447-81-5
2-Methyl-3-(1H-pyrazol-5-yl)pyrazine
CAS 195447-81-5C8H8N4
2-(1H-Pyrazol-3-yl)pyrazine chemical structure, C7H6N4, CAS 111781-54-5
2-(1H-Pyrazol-3-yl)pyrazine
CAS 111781-54-5C7H6N4
5-Pyrazin-2-yl-1H-pyrazole-3-carboxylic acid chemical structure, C8H6N4O2, CAS 1029108-75-5
5-Pyrazin-2-yl-1H-pyrazole-3-carboxylic acid
CAS 1029108-75-5C8H6N4O2
2-(5-Methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C8H8N4, CAS 192711-19-6
2-(5-Methyl-1H-pyrazol-3-yl)pyrazine
CAS 192711-19-6C8H8N4
2-[5-(Trifluoromethyl)-1H-pyrazol-3-yl]pyrazine chemical structure, C8H5F3N4, CAS 188920-84-5
2-[5-(Trifluoromethyl)-1H-pyrazol-3-yl]pyrazine
CAS 188920-84-5C8H5F3N4
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl trifluoromethanesulfonate chemical structure, C10H9F3N4O3S, CAS 1279106-19-2
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl trifluoromethanesulfonate
CAS 1279106-19-2C10H9F3N4O3S
3-(Pyrazin-2-yl)-1H-pyrazol-4-amine chemical structure, C7H7N5, CAS 896467-28-0
3-(Pyrazin-2-yl)-1H-pyrazol-4-amine
CAS 896467-28-0C7H7N5
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C10H10N4O, CAS 1339536-89-8
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 1339536-89-8C10H10N4O
3-(Pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C8H6N4O, CAS 1343011-99-3
3-(Pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 1343011-99-3C8H6N4O
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C9H8N4O, CAS 1340455-25-5
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 1340455-25-5C9H8N4O
(3-(Pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine chemical structure, C8H9N5, CAS 1350478-03-3
(3-(Pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
CAS 1350478-03-3C8H9N5
N-Methyl-1-(3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine chemical structure, C9H11N5, CAS 1347137-05-6
N-Methyl-1-(3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
CAS 1347137-05-6C9H11N5
1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C12H14N4O, CAS 1409686-48-1
1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 1409686-48-1C12H14N4O
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C10H10N4O2, CAS 1339598-00-3
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 1339598-00-3C10H10N4O2
3-(Pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C8H6N4O2, CAS 1344018-75-2
3-(Pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 1344018-75-2C8H6N4O2
3-(Pyrazin-2-yl)-1H-pyrazole-5-carbaldehyde chemical structure, C8H6N4O, CAS 1347231-55-3
3-(Pyrazin-2-yl)-1H-pyrazole-5-carbaldehyde
CAS 1347231-55-3C8H6N4O
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C9H8N4O2, CAS 1339822-86-4
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 1339822-86-4C9H8N4O2
2-(4-Bromo-1H-pyrazol-3-yl)pyrazine chemical structure, C7H5BrN4, CAS 1334638-80-0
2-(4-Bromo-1H-pyrazol-3-yl)pyrazine
CAS 1334638-80-0C7H5BrN4
2-(4-Nitro-1H-pyrazol-3-yl)pyrazine chemical structure, C7H5N5O2, CAS 1342039-78-4
2-(4-Nitro-1H-pyrazol-3-yl)pyrazine
CAS 1342039-78-4C7H5N5O2
5-(1-Methyl-1H-pyrazol-5-yl)pyrazin-2-amine chemical structure, C8H9N5, CAS 1491914-15-8
5-(1-Methyl-1H-pyrazol-5-yl)pyrazin-2-amine
CAS 1491914-15-8C8H9N5
2-Chloro-3-(1-methyl-1H-pyrazol-5-yl)pyrazine chemical structure, C8H7ClN4, CAS 1495437-37-0
2-Chloro-3-(1-methyl-1H-pyrazol-5-yl)pyrazine
CAS 1495437-37-0C8H7ClN4
2-Chloro-6-(1-methyl-1H-pyrazol-5-yl)pyrazine chemical structure, C8H7ClN4, CAS 1490003-92-3
2-Chloro-6-(1-methyl-1H-pyrazol-5-yl)pyrazine
CAS 1490003-92-3C8H7ClN4
5-[3-Methyl-6-(2-methylpropyl)pyrazin-2-yl]-1H-pyrazol-3-amine chemical structure, C12H17N5, CAS 1332731-05-1
5-[3-Methyl-6-(2-methylpropyl)pyrazin-2-yl]-1H-pyrazol-3-amine
CAS 1332731-05-1C12H17N5
1,4-Dimethyl-3-(5-methyl-2-pyrazinyl)-1H-pyrazol-5-amine chemical structure, C10H13N5, CAS 1414568-79-8
1,4-Dimethyl-3-(5-methyl-2-pyrazinyl)-1H-pyrazol-5-amine
CAS 1414568-79-8C10H13N5