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Murcko scaffold

2-(1H-Pyrazol-3-yl)pyrazine scaffold

323 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
323
With full pages
4
Scaffold SMILES

c1cnc(-c2ccn[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-3-yl)pyrazine page
Murcko scaffold c1cnc(-c2ccn[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 323 chemicals

3,3-Dimethyl-N-{2-[3-(pyrazin-2-yl)-1H-pyrazol-1-yl]ethyl}butanamide chemical structure, C15H21N5O, CAS 2034510-94-4
3,3-Dimethyl-N-{2-[3-(pyrazin-2-yl)-1H-pyrazol-1-yl]ethyl}butanamide
CAS 2034510-94-4C15H21N5O
2-(N-Methylmethylsulfonamido)-N-(2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)acetamide chemical structure, C13H18N6O3S, CAS 2034415-16-0
2-(N-Methylmethylsulfonamido)-N-(2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)acetamide
CAS 2034415-16-0C13H18N6O3S
Ethyl 4-oxo-4-((2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)amino)butanoate chemical structure, C15H19N5O3, CAS 2034504-84-0
Ethyl 4-oxo-4-((2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)amino)butanoate
CAS 2034504-84-0C15H19N5O3
1-(tert-Butyl)-3-(2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)urea chemical structure, C14H20N6O, CAS 2034415-43-3
1-(tert-Butyl)-3-(2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)urea
CAS 2034415-43-3C14H20N6O
1-(2-Methoxyethyl)-3-(2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)urea chemical structure, C13H18N6O2, CAS 2034600-43-4
1-(2-Methoxyethyl)-3-(2-(3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethyl)urea
CAS 2034600-43-4C13H18N6O2
Dimethyl({2-[3-(pyrazin-2-yl)-1H-pyrazol-1-yl]ethyl}sulfamoyl)amine chemical structure, C11H16N6O2S, CAS 2034505-36-5
Dimethyl({2-[3-(pyrazin-2-yl)-1H-pyrazol-1-yl]ethyl}sulfamoyl)amine
CAS 2034505-36-5C11H16N6O2S
Ethyl ((1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)carbamate chemical structure, C12H15N5O2, CAS 2034507-41-8
Ethyl ((1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)carbamate
CAS 2034507-41-8C12H15N5O2
N-((1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)pivalamide chemical structure, C14H19N5O, CAS 2034456-69-2
N-((1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)pivalamide
CAS 2034456-69-2C14H19N5O
Ethyl 4-(((1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)amino)-4-oxobutanoate chemical structure, C15H19N5O3, CAS 2034550-61-1
Ethyl 4-(((1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)amino)-4-oxobutanoate
CAS 2034550-61-1C15H19N5O3
N-((1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)propane-1-sulfonamide chemical structure, C12H17N5O2S, CAS 2034373-92-5
N-((1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methyl)propane-1-sulfonamide
CAS 2034373-92-5C12H17N5O2S
Dimethyl({[1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl]methyl}sulfamoyl)amine chemical structure, C11H16N6O2S, CAS 2034323-70-9
Dimethyl({[1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl]methyl}sulfamoyl)amine
CAS 2034323-70-9C11H16N6O2S
2-(3-(Pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine chemical structure, C9H11N5, CAS 2092548-70-2
2-(3-(Pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
CAS 2092548-70-2C9H11N5
(1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine chemical structure, C9H11N5, CAS 2005865-03-0
(1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
CAS 2005865-03-0C9H11N5
2-(3-(Pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C9H8N4O2, CAS 1019007-59-0
2-(3-(Pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 1019007-59-0C9H8N4O2
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C9H8N4O2, CAS 2091184-83-5
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2091184-83-5C9H8N4O2
2-(3-(Pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C9H7N5, CAS 2098036-01-0
2-(3-(Pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2098036-01-0C9H7N5
Methyl 3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C9H8N4O2, CAS 1873310-01-0
Methyl 3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate
CAS 1873310-01-0C9H8N4O2
Methyl 1-methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C10H10N4O2, CAS 2098065-72-4
Methyl 1-methyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate
CAS 2098065-72-4C10H10N4O2
Methyl 1-ethyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C11H12N4O2, CAS 2097983-12-3
Methyl 1-ethyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylate
CAS 2097983-12-3C11H12N4O2
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C10H10N4O2, CAS 2092465-79-5
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2092465-79-5C10H10N4O2
1-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C11H12N4O2, CAS 2098065-74-6
1-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2098065-74-6C11H12N4O2
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C10H9FN4O2, CAS 2098130-95-9
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2098130-95-9C10H9FN4O2
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C11H8N4O2, CAS 2098065-82-6
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2098065-82-6C11H8N4O2
1-(Cyanomethyl)-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C10H7N5O2, CAS 2097983-14-5
1-(Cyanomethyl)-3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid
CAS 2097983-14-5C10H7N5O2