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Murcko scaffold

2-(1H-Pyrazol-3-yl)pyrazine scaffold

323 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
323
With full pages
4
Scaffold SMILES

c1cnc(-c2ccn[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-3-yl)pyrazine page
Murcko scaffold c1cnc(-c2ccn[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 289 to 323 of 323 chemicals

2-(1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-ol chemical structure, C12H12N4O, CAS 2097986-74-6
2-(1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-ol
CAS 2097986-74-6C12H12N4O
2-(1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine chemical structure, C10H13N5, CAS 2090577-66-3
2-(1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine
CAS 2090577-66-3C10H13N5
2-(1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine chemical structure, C11H15N5, CAS 2098022-01-4
2-(1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine
CAS 2098022-01-4C11H15N5
2-(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine chemical structure, C11H14FN5, CAS 2098011-20-0
2-(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine
CAS 2098011-20-0C11H14FN5
2-(1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine chemical structure, C12H13N5, CAS 2097979-14-9
2-(1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine
CAS 2097979-14-9C12H13N5
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C9H11N5, CAS 2092818-52-3
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2092818-52-3C9H11N5
1-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C10H13N5, CAS 2091127-38-5
1-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2091127-38-5C10H13N5
1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C11H15N5, CAS 2092699-31-3
1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2092699-31-3C11H15N5
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C10H9N5, CAS 2090254-65-0
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2090254-65-0C10H9N5
2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C9H8N6, CAS 2091576-68-8
2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2091576-68-8C9H8N6
2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetimidamide chemical structure, C9H11N7, CAS 2090949-84-9
2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetimidamide
CAS 2090949-84-9C9H11N7
Methyl 2-(5-amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetate chemical structure, C10H11N5O2, CAS 2098047-76-6
Methyl 2-(5-amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetate
CAS 2098047-76-6C10H11N5O2
2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C9H9N5O2, CAS 2097966-06-6
2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 2097966-06-6C9H9N5O2
1-(2-Azidoethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C9H10N8, CAS 2098020-16-5
1-(2-Azidoethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2098020-16-5C9H10N8
1-(2-Aminoethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C9H12N6, CAS 2098047-81-3
1-(2-Aminoethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2098047-81-3C9H12N6
tert-Butyl 6-(1-methyl-1H-pyrazol-3-yl)pyrazine-2-carboxylate chemical structure, C13H16N4O2, CAS 1708990-60-6
tert-Butyl 6-(1-methyl-1H-pyrazol-3-yl)pyrazine-2-carboxylate
CAS 1708990-60-6C13H16N4O2
1-Methyl-5-(pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C9H8N4O2, CAS 1857792-36-9
1-Methyl-5-(pyrazin-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 1857792-36-9C9H8N4O2
3-(Pyrazin-2-yl)-1H-pyrazole-4-carboximidamide chemical structure, C8H8N6, CAS 2097985-58-3
3-(Pyrazin-2-yl)-1H-pyrazole-4-carboximidamide
CAS 2097985-58-3C8H8N6
5-Chloro-6-(1-methyl-1H-pyrazol-3-yl)-2-pyrazinamine chemical structure, C8H8ClN5, CAS 2266614-61-1
5-Chloro-6-(1-methyl-1H-pyrazol-3-yl)-2-pyrazinamine
CAS 2266614-61-1C8H8ClN5
1-Methyl-5-(pyrazin-2-yl)-1H-pyrazol-4-amine chemical structure, C8H9N5, CAS 2111510-61-1
1-Methyl-5-(pyrazin-2-yl)-1H-pyrazol-4-amine
CAS 2111510-61-1C8H9N5
3-(3-Methyl-2-pyrazinyl)-1H-pyrazole-1-propanal chemical structure, C11H12N4O, CAS 439106-91-9
3-(3-Methyl-2-pyrazinyl)-1H-pyrazole-1-propanal
CAS 439106-91-9C11H12N4O
4-Fluoro-1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C8H8FN5, CAS 2138521-18-1
4-Fluoro-1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2138521-18-1C8H8FN5
4-Ethyl-1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine chemical structure, C10H13N5, CAS 2138083-27-7
4-Ethyl-1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-amine
CAS 2138083-27-7C10H13N5
1-Methyl-5-(3-methylpyrazin-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C10H10N4O2, CAS 2228399-11-7
1-Methyl-5-(3-methylpyrazin-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 2228399-11-7C10H10N4O2