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Murcko scaffold

2-(1H-Pyrazol-3-yl)pyrazine scaffold

323 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
323
With full pages
4
Scaffold SMILES

c1cnc(-c2ccn[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-3-yl)pyrazine page
Murcko scaffold c1cnc(-c2ccn[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 323 chemicals

1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C10H9N5, CAS 2098136-32-2
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 2098136-32-2C10H9N5
1-(Cyanomethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C10H6N6, CAS 2098018-50-7
1-(Cyanomethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 2098018-50-7C10H6N6
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C10H8FN5, CAS 2098082-93-8
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 2098082-93-8C10H8FN5
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C11H7N5, CAS 2098014-32-3
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 2098014-32-3C11H7N5
2-(4-Cyano-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C10H7N5O2, CAS 2097985-47-0
2-(4-Cyano-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 2097985-47-0C10H7N5O2
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide chemical structure, C9H10N6, CAS 2098089-55-3
1-Methyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide
CAS 2098089-55-3C9H10N6
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide chemical structure, C10H12N6, CAS 2097985-61-8
1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide
CAS 2097985-61-8C10H12N6
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide chemical structure, C10H11FN6, CAS 2098089-66-6
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide
CAS 2098089-66-6C10H11FN6
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide chemical structure, C11H10N6, CAS 2098014-73-2
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carboximidamide
CAS 2098014-73-2C11H10N6
2-(4-Formyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C10H7N5O, CAS 2091653-98-2
2-(4-Formyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2091653-98-2C10H7N5O
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C10H9FN4O, CAS 2098077-42-8
1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 2098077-42-8C10H9FN4O
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C11H8N4O, CAS 2092582-99-3
1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 2092582-99-3C11H8N4O
2-(4-Formyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C10H8N4O3, CAS 2097971-75-8
2-(4-Formyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 2097971-75-8C10H8N4O3
(1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C12H17N5, CAS 2098077-65-5
(1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine
CAS 2098077-65-5C12H17N5
(1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C10H13N5, CAS 2090573-96-7
(1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine
CAS 2090573-96-7C10H13N5
(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C10H12FN5, CAS 2098077-71-3
(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine
CAS 2098077-71-3C10H12FN5
(1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C11H11N5, CAS 2092793-05-8
(1-(Prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine
CAS 2092793-05-8C11H11N5
2-(4-(Azidomethyl)-1-methyl-1H-pyrazol-3-yl)pyrazine chemical structure, C9H9N7, CAS 2098143-92-9
2-(4-(Azidomethyl)-1-methyl-1H-pyrazol-3-yl)pyrazine
CAS 2098143-92-9C9H9N7
2-(4-(Azidomethyl)-1-ethyl-1H-pyrazol-3-yl)pyrazine chemical structure, C10H11N7, CAS 2098086-80-5
2-(4-(Azidomethyl)-1-ethyl-1H-pyrazol-3-yl)pyrazine
CAS 2098086-80-5C10H11N7
1-(1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)-N-methylmethanamine chemical structure, C11H15N5, CAS 2098143-97-4
1-(1-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)-N-methylmethanamine
CAS 2098143-97-4C11H15N5
1-(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)-N-methylmethanamine chemical structure, C11H14FN5, CAS 2097986-33-7
1-(1-(2-Fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)-N-methylmethanamine
CAS 2097986-33-7C11H14FN5
N-Methyl-1-(1-(prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C12H13N5, CAS 2098015-23-5
N-Methyl-1-(1-(prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)methanamine
CAS 2098015-23-5C12H13N5
2-(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)acetic acid chemical structure, C9H8N4O2, CAS 2091293-77-3
2-(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)acetic acid
CAS 2091293-77-3C9H8N4O2
2-(1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)acetic acid chemical structure, C10H10N4O2, CAS 2090946-16-8
2-(1-Methyl-3-(pyrazin-2-yl)-1H-pyrazol-4-yl)acetic acid
CAS 2090946-16-8C10H10N4O2