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Murcko scaffold

2-(1H-Pyrazol-3-yl)pyrazine scaffold

323 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
323
With full pages
4
Scaffold SMILES

c1cnc(-c2ccn[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-3-yl)pyrazine page
Murcko scaffold c1cnc(-c2ccn[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 323 chemicals

2-(5-Methyl-1-(prop-2-yn-1-yl)-1H-pyrazol-3-yl)pyrazine chemical structure, C11H10N4, CAS 2098110-25-7
2-(5-Methyl-1-(prop-2-yn-1-yl)-1H-pyrazol-3-yl)pyrazine
CAS 2098110-25-7C11H10N4
Methyl 2-(5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetimidate chemical structure, C11H13N5O, CAS 2097986-18-8
Methyl 2-(5-methyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetimidate
CAS 2097986-18-8C11H13N5O
(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)methanol chemical structure, C10H12N4O, CAS 2092530-14-6
(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)methanol
CAS 2092530-14-6C10H12N4O
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C11H12N4O2, CAS 2098070-52-9
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 2098070-52-9C11H12N4O2
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C11H11N5, CAS 2097964-57-1
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2097964-57-1C11H11N5
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetimidamide chemical structure, C11H14N6, CAS 2098070-56-3
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetimidamide
CAS 2098070-56-3C11H14N6
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine chemical structure, C11H15N5, CAS 2098134-47-3
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
CAS 2098134-47-3C11H15N5
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol chemical structure, C11H14N4O, CAS 2098110-40-6
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol
CAS 2098110-40-6C11H14N4O
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetaldehyde chemical structure, C11H12N4O, CAS 2098132-86-4
2-(5-Ethyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetaldehyde
CAS 2098132-86-4C11H12N4O
2-(5-Ethyl-1-(prop-2-yn-1-yl)-1H-pyrazol-3-yl)pyrazine chemical structure, C12H12N4, CAS 2098070-62-1
2-(5-Ethyl-1-(prop-2-yn-1-yl)-1H-pyrazol-3-yl)pyrazine
CAS 2098070-62-1C12H12N4
(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)methanol chemical structure, C11H14N4O, CAS 2091693-19-3
(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)methanol
CAS 2091693-19-3C11H14N4O
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile chemical structure, C12H13N5, CAS 2097986-22-4
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS 2097986-22-4C12H13N5
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine chemical structure, C12H17N5, CAS 2098047-10-8
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
CAS 2098047-10-8C12H17N5
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol chemical structure, C12H16N4O, CAS 2098006-52-9
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol
CAS 2098006-52-9C12H16N4O
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetaldehyde chemical structure, C12H14N4O, CAS 2098070-65-4
2-(5-Isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)acetaldehyde
CAS 2098070-65-4C12H14N4O
2-(5-Isopropyl-1-(prop-2-yn-1-yl)-1H-pyrazol-3-yl)pyrazine chemical structure, C13H14N4, CAS 2097964-62-8
2-(5-Isopropyl-1-(prop-2-yn-1-yl)-1H-pyrazol-3-yl)pyrazine
CAS 2097964-62-8C13H14N4
Methyl 3-(pyrazin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C9H8N4O2, CAS 2098131-57-6
Methyl 3-(pyrazin-2-yl)-1H-pyrazole-4-carboxylate
CAS 2098131-57-6C9H8N4O2
(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)methanol chemical structure, C8H8N4O, CAS 2090265-84-0
(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)methanol
CAS 2090265-84-0C8H8N4O
2-(4-(Chloromethyl)-1H-pyrazol-3-yl)pyrazine chemical structure, C8H7ClN4, CAS 2091139-37-4
2-(4-(Chloromethyl)-1H-pyrazol-3-yl)pyrazine
CAS 2091139-37-4C8H7ClN4
3-(Pyrazin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C8H5N5, CAS 2098006-13-2
3-(Pyrazin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 2098006-13-2C8H5N5
2-(4-(Azidomethyl)-1H-pyrazol-3-yl)pyrazine chemical structure, C8H7N7, CAS 2097986-79-1
2-(4-(Azidomethyl)-1H-pyrazol-3-yl)pyrazine
CAS 2097986-79-1C8H7N7
3-(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)propanoic acid chemical structure, C10H10N4O2, CAS 2098006-09-6
3-(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)propanoic acid
CAS 2098006-09-6C10H10N4O2
Methyl 3-(3-(pyrazin-2-yl)-1H-pyrazol-4-yl)propanoate chemical structure, C11H12N4O2, CAS 2098111-92-1
Methyl 3-(3-(pyrazin-2-yl)-1H-pyrazol-4-yl)propanoate
CAS 2098111-92-1C11H12N4O2
3-(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)propanamide chemical structure, C10H11N5O, CAS 2098112-01-5
3-(3-(Pyrazin-2-yl)-1H-pyrazol-4-yl)propanamide
CAS 2098112-01-5C10H11N5O