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Murcko scaffold

Ring system with 3 rings and 17 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
11
With full pages
3
Scaffold SMILES

c1ccc(CSc2nc3ncccc3[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2nc3ncccc3[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-[(3-Chlorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine chemical structure, C13H10ClN3S, CAS 401596-45-0
2-[(3-Chlorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine
CAS 401596-45-0C13H10ClN3S
RefChem:381485 chemical structure, C13H9Cl2N3S, CAS 5996-11-2
RefChem:381485
CAS 5996-11-2C13H9Cl2N3S
2-(3-Trifluoromethyl-benzylsulfanyl)-3H-imidazo[4,5-b]pyridine chemical structure, C14H10F3N3S, CAS 333409-45-3
2-(3-Trifluoromethyl-benzylsulfanyl)-3H-imidazo[4,5-b]pyridine
CAS 333409-45-3C14H10F3N3S
3H-Imidazo[4,5-b]pyridine, 2-(2-chlorobenzylthio)- chemical structure, C13H10ClN3S, CAS 354559-00-5
3H-Imidazo[4,5-b]pyridine, 2-(2-chlorobenzylthio)-
CAS 354559-00-5C13H10ClN3S
2-[(4-Nitrobenzyl)sulfanyl]-3H-imidazo[4,5-b]pyridine chemical structure, C13H10N4O2S, CAS 355825-12-6
2-[(4-Nitrobenzyl)sulfanyl]-3H-imidazo[4,5-b]pyridine
CAS 355825-12-6C13H10N4O2S
6-Bromo-2-[(4-fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine chemical structure, C13H9BrFN3S, CAS 393123-82-5
6-Bromo-2-[(4-fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine
CAS 393123-82-5C13H9BrFN3S
2-[(2-Fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine chemical structure, C13H10FN3S, CAS 353500-15-9
2-[(2-Fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine
CAS 353500-15-9C13H10FN3S
6-Bromo-2-[(2-fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine chemical structure, C13H9BrFN3S, CAS 356088-73-8
6-Bromo-2-[(2-fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine
CAS 356088-73-8C13H9BrFN3S
6-Bromo-2-[(4-nitrophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine chemical structure, C13H9BrN4O2S, CAS 714234-11-4
6-Bromo-2-[(4-nitrophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine
CAS 714234-11-4C13H9BrN4O2S
2-(((6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio)methyl)benzonitrile chemical structure, C14H9BrN4S, CAS 355827-05-3
2-(((6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio)methyl)benzonitrile
CAS 355827-05-3C14H9BrN4S
6-Chloro-2-[(3-fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine chemical structure, C13H9ClFN3S, CAS 877782-26-8
6-Chloro-2-[(3-fluorophenyl)methylsulfanyl]-1H-imidazo[4,5-b]pyridine
CAS 877782-26-8C13H9ClFN3S