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Murcko scaffold

Ring system with 3 rings and 17 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
17
With full pages
4
Scaffold SMILES

c1ccc(-c2ccc(-c3cscn3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccc(-c3cscn3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-Amino-4-(4-biphenylyl)thiazole chemical structure, C15H12N2S, CAS 2834-79-9
2-Amino-4-(4-biphenylyl)thiazole
CAS 2834-79-9C15H12N2S
4-(4-Biphenylyl)-2-methylthiazole chemical structure, C16H13NS, CAS 24864-19-5
4-(4-Biphenylyl)-2-methylthiazole
CAS 24864-19-5C16H13NS
N-(4-Biphenyl-4-yl-thiazol-2-yl)-acetamide chemical structure, C17H14N2OS, CAS 330593-37-8
N-(4-Biphenyl-4-yl-thiazol-2-yl)-acetamide
CAS 330593-37-8C17H14N2OS
N-(4-Biphenyl-4-yl-thiazol-2-yl)-2-methoxy-acetamide chemical structure, C18H16N2O2S, CAS 691860-74-9
N-(4-Biphenyl-4-yl-thiazol-2-yl)-2-methoxy-acetamide
CAS 691860-74-9C18H16N2O2S
N-(4-Biphenyl-4-yl-1,3-thiazol-2-yl)-2-chloroacetamide chemical structure, C17H13ClN2OS, CAS 726153-55-5
N-(4-Biphenyl-4-yl-1,3-thiazol-2-yl)-2-chloroacetamide
CAS 726153-55-5C17H13ClN2OS
4-(4-Phenylphenyl)-N-(prop-2-en-1-yl)-1,3-thiazol-2-amine chemical structure, C18H16N2S, CAS 560995-23-5
4-(4-Phenylphenyl)-N-(prop-2-en-1-yl)-1,3-thiazol-2-amine
CAS 560995-23-5C18H16N2S
4-(4'-Bromobiphenyl-4-yl)thiazol-2-ylamine chemical structure, C15H11BrN2S, CAS 676348-26-8
4-(4'-Bromobiphenyl-4-yl)thiazol-2-ylamine
CAS 676348-26-8C15H11BrN2S
1-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)guanidine chemical structure, C16H14N4S, CAS 123309-91-1
1-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)guanidine
CAS 123309-91-1C16H14N4S
[4-(4-Phenylphenyl)-1,3-thiazol-2-yl]methanamine chemical structure, C16H14N2S, CAS 643723-51-7
[4-(4-Phenylphenyl)-1,3-thiazol-2-yl]methanamine
CAS 643723-51-7C16H14N2S
N-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)isobutyramide chemical structure, C19H18N2OS, CAS 317854-00-5
N-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)isobutyramide
CAS 317854-00-5C19H18N2OS
N-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)pentanamide chemical structure, C20H20N2OS, CAS 387883-09-2
N-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)pentanamide
CAS 387883-09-2C20H20N2OS
4-([1,1'-Biphenyl]-4-yl)-5-methylthiazol-2-amine chemical structure, C16H14N2S, CAS 206555-42-2
4-([1,1'-Biphenyl]-4-yl)-5-methylthiazol-2-amine
CAS 206555-42-2C16H14N2S
Methyl 4-([1,1'-biphenyl]-4-yl)-2-bromothiazole-5-carboxylate chemical structure, C17H12BrNO2S, CAS 1206908-04-4
Methyl 4-([1,1'-biphenyl]-4-yl)-2-bromothiazole-5-carboxylate
CAS 1206908-04-4C17H12BrNO2S
4-(4'-Bromo-4-biphenylyl)-2-methylthiazole chemical structure, C16H12BrNS, CAS 1421262-90-9
4-(4'-Bromo-4-biphenylyl)-2-methylthiazole
CAS 1421262-90-9C16H12BrNS
4-([1,1'-Biphenyl]-4-yl)-5-(methylsulfonyl)thiazol-2-amine chemical structure, C16H14N2O2S2, CAS 1707379-58-5
4-([1,1'-Biphenyl]-4-yl)-5-(methylsulfonyl)thiazol-2-amine
CAS 1707379-58-5C16H14N2O2S2
4-([1,1'-Biphenyl]-4-yl)-5-(ethylsulfonyl)thiazol-2-amine chemical structure, C17H16N2O2S2, CAS 1708269-54-8
4-([1,1'-Biphenyl]-4-yl)-5-(ethylsulfonyl)thiazol-2-amine
CAS 1708269-54-8C17H16N2O2S2
4-Biphenyl-4-YL-thiazol-2-ylamine hydrobromide chemical structure, C15H13BrN2S, CAS 42056-63-3
4-Biphenyl-4-YL-thiazol-2-ylamine hydrobromide
CAS 42056-63-3C15H13BrN2S