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Murcko scaffold

1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-phenylurea scaffold

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
40
With full pages
14
Scaffold SMILES

O=C(Nc1ccccc1)NC1CCS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-phenylurea page
Murcko scaffold O=C(Nc1ccccc1)NC1CCS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

1-(4-Chlorophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C11H13ClN2O3S, CAS 300716-72-7
1-(4-Chlorophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 300716-72-7C11H13ClN2O3S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(4-methylphenyl)urea chemical structure, C12H16N2O3S, CAS 300716-73-8
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(4-methylphenyl)urea
CAS 300716-73-8C12H16N2O3S
1-(3-(Dimethylamino)phenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C13H19N3O3S, CAS 294668-87-4
1-(3-(Dimethylamino)phenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 294668-87-4C13H19N3O3S
1-(4-Hydroxy-1,1-dioxothiolan-3-yl)-3-phenylurea chemical structure, C11H14N2O4S, CAS 77691-89-5
1-(4-Hydroxy-1,1-dioxothiolan-3-yl)-3-phenylurea
CAS 77691-89-5C11H14N2O4S
1-(3-Methyl-1,1-dioxothiolan-3-yl)-3-(3-nitrophenyl)urea chemical structure, C12H15N3O5S, CAS 305855-93-0
1-(3-Methyl-1,1-dioxothiolan-3-yl)-3-(3-nitrophenyl)urea
CAS 305855-93-0C12H15N3O5S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-phenylurea chemical structure, C11H14N2O3S, CAS 24373-81-7
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-phenylurea
CAS 24373-81-7C11H14N2O3S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(m-tolyl)urea chemical structure, C12H16N2O3S, CAS 428449-64-3
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(m-tolyl)urea
CAS 428449-64-3C12H16N2O3S
1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-phenylurea chemical structure, C12H16N2O3S, CAS 425679-85-2
1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-phenylurea
CAS 425679-85-2C12H16N2O3S
1-(3-Hydroxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C12H16N2O4S, CAS 425681-96-5
1-(3-Hydroxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 425681-96-5C12H16N2O4S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(4-methoxyphenyl)urea chemical structure, C12H16N2O4S, CAS 507252-92-8
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(4-methoxyphenyl)urea
CAS 507252-92-8C12H16N2O4S
1-(3-(Dimethylamino)phenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C14H21N3O3S, CAS 507257-30-9
1-(3-(Dimethylamino)phenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 507257-30-9C14H21N3O3S
1-(3-Bromophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C11H13BrN2O3S, CAS 443652-94-6
1-(3-Bromophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 443652-94-6C11H13BrN2O3S
1-(1,1-Dioxothiolan-3-yl)-3-(3-nitrophenyl)urea chemical structure, C11H13N3O5S, CAS 443652-86-6
1-(1,1-Dioxothiolan-3-yl)-3-(3-nitrophenyl)urea
CAS 443652-86-6C11H13N3O5S
1-(1,1-Dioxothiolan-3-yl)-3-(2-methylphenyl)urea chemical structure, C12H16N2O3S, CAS 630065-19-9
1-(1,1-Dioxothiolan-3-yl)-3-(2-methylphenyl)urea
CAS 630065-19-9C12H16N2O3S
1-(3-Chlorophenyl)-3-(1,1-dioxothiolan-3-yl)urea chemical structure, C11H13ClN2O3S, CAS 321978-78-3
1-(3-Chlorophenyl)-3-(1,1-dioxothiolan-3-yl)urea
CAS 321978-78-3C11H13ClN2O3S
1-(4-Chloro-1,1-dioxothiolan-3-yl)-3-phenylurea chemical structure, C11H13ClN2O3S, CAS 321580-51-2
1-(4-Chloro-1,1-dioxothiolan-3-yl)-3-phenylurea
CAS 321580-51-2C11H13ClN2O3S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-1-methyl-3-phenylurea chemical structure, C12H16N2O3S, CAS 425668-19-5
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-1-methyl-3-phenylurea
CAS 425668-19-5C12H16N2O3S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(2-methoxyphenyl)urea chemical structure, C12H16N2O4S, CAS 507253-00-1
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(2-methoxyphenyl)urea
CAS 507253-00-1C12H16N2O4S
1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-(3-methylphenyl)urea chemical structure, C13H18N2O3S, CAS 507256-13-5
1-(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)-3-(3-methylphenyl)urea
CAS 507256-13-5C13H18N2O3S
1-(4-Methoxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C13H18N2O4S, CAS 507256-36-2
1-(4-Methoxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 507256-36-2C13H18N2O4S
1-(2-Methoxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C13H18N2O4S, CAS 507256-40-8
1-(2-Methoxyphenyl)-3-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 507256-40-8C13H18N2O4S
1-(3,4-Dichlorophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C11H12Cl2N2O3S, CAS 630065-22-4
1-(3,4-Dichlorophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 630065-22-4C11H12Cl2N2O3S
1-(2-Chlorophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea chemical structure, C11H13ClN2O3S, CAS 630065-25-7
1-(2-Chlorophenyl)-3-(1,1-dioxidotetrahydrothiophen-3-yl)urea
CAS 630065-25-7C11H13ClN2O3S
1-(4-Chloro-1,1-dioxothiolan-3-yl)-3-(4-chlorophenyl)urea chemical structure, C11H12Cl2N2O3S, CAS 302902-45-0
1-(4-Chloro-1,1-dioxothiolan-3-yl)-3-(4-chlorophenyl)urea
CAS 302902-45-0C11H12Cl2N2O3S