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Murcko scaffold

Ring system with 3 rings and 20 atoms

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
34
With full pages
4
Scaffold SMILES

c1ccc(NCc2ccc(-c3ccccc3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(NCc2ccc(-c3ccccc3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

N-{4-[([1,1'-Biphenyl]-4-ylmethyl)amino]phenyl}acetamide chemical structure, C21H20N2O, CAS 714206-01-6
N-{4-[([1,1'-Biphenyl]-4-ylmethyl)amino]phenyl}acetamide
CAS 714206-01-6C21H20N2O
N-{4-[(Biphenyl-4-ylmethyl)amino]phenyl}propanamide chemical structure, C22H22N2O, CAS 723753-66-0
N-{4-[(Biphenyl-4-ylmethyl)amino]phenyl}propanamide
CAS 723753-66-0C22H22N2O
2-Methyl-N-[4-[(4-phenylphenyl)methylamino]phenyl]propanamide chemical structure, C23H24N2O, CAS 723753-67-1
2-Methyl-N-[4-[(4-phenylphenyl)methylamino]phenyl]propanamide
CAS 723753-67-1C23H24N2O
N-[4-[(4-Phenylphenyl)methylamino]phenyl]butanamide chemical structure, C23H24N2O, CAS 717863-09-7
N-[4-[(4-Phenylphenyl)methylamino]phenyl]butanamide
CAS 717863-09-7C23H24N2O
Methyl 2-[N-(tert-Butoxycarbonyl)-N-[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate chemical structure, C27H25N3O6, CAS 139481-38-2
Methyl 2-[N-(tert-Butoxycarbonyl)-N-[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate
CAS 139481-38-2C27H25N3O6
Ethyl 2-{[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino}-3-nitrobenzoate chemical structure, C23H19N3O4, CAS 136285-67-1
Ethyl 2-{[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino}-3-nitrobenzoate
CAS 136285-67-1C23H19N3O4
4-{[([1,1'-Biphenyl]-4-yl)methyl]amino}benzoic acid chemical structure, C20H17NO2, CAS 61439-49-4
4-{[([1,1'-Biphenyl]-4-yl)methyl]amino}benzoic acid
CAS 61439-49-4C20H17NO2
Ethyl 4-{[([1,1'-biphenyl]-4-yl)methyl]amino}benzoate chemical structure, C22H21NO2, CAS 61439-48-3
Ethyl 4-{[([1,1'-biphenyl]-4-yl)methyl]amino}benzoate
CAS 61439-48-3C22H21NO2
Methyl 2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-nitrobenzoate chemical structure, C22H17N3O4, CAS 139481-28-0
Methyl 2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-nitrobenzoate
CAS 139481-28-0C22H17N3O4
Methyl 4'-{[2-(methoxycarbonyl)-6-nitroanilino]methyl}[1,1'-biphenyl]-2-carboxylate chemical structure, C23H20N2O6, CAS 139481-36-0
Methyl 4'-{[2-(methoxycarbonyl)-6-nitroanilino]methyl}[1,1'-biphenyl]-2-carboxylate
CAS 139481-36-0C23H20N2O6
Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate chemical structure, C22H19N3O2, CAS 136304-78-4
Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate
CAS 136304-78-4C22H19N3O2
Ethyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate chemical structure, C23H21N3O2, CAS 136285-69-3
Ethyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate
CAS 136285-69-3C23H21N3O2
Ethyl 3-{acetyl[(2'-fluoro[1,1'-biphenyl]-4-yl)methyl]amino}-4-nitrobenzoate chemical structure, C24H21FN2O5, CAS 193013-77-3
Ethyl 3-{acetyl[(2'-fluoro[1,1'-biphenyl]-4-yl)methyl]amino}-4-nitrobenzoate
CAS 193013-77-3C24H21FN2O5
Methyl 3-amino-2-[[4-(2-carbamoylphenyl)phenyl]methylamino]benzoate chemical structure, C22H21N3O3, CAS 147404-75-9
Methyl 3-amino-2-[[4-(2-carbamoylphenyl)phenyl]methylamino]benzoate
CAS 147404-75-9C22H21N3O3
Methyl 2-(2'-carbamoylbiphenyl-4-yl)methylamino-3-nitrobenzoate chemical structure, C22H19N3O5, CAS 147404-74-8
Methyl 2-(2'-carbamoylbiphenyl-4-yl)methylamino-3-nitrobenzoate
CAS 147404-74-8C22H19N3O5
N-([1,1'-Biphenyl]-4-ylmethyl)-2-chloroaniline chemical structure, C19H16ClN, CAS 356530-17-1
N-([1,1'-Biphenyl]-4-ylmethyl)-2-chloroaniline
CAS 356530-17-1C19H16ClN
N-([1,1'-Biphenyl]-4-ylmethyl)-3-chloro-2-methylaniline chemical structure, C20H18ClN, CAS 356530-33-1
N-([1,1'-Biphenyl]-4-ylmethyl)-3-chloro-2-methylaniline
CAS 356530-33-1C20H18ClN
N-([1,1'-Biphenyl]-4-ylmethyl)-4-ethoxyaniline chemical structure, C21H21NO, CAS 356530-22-8
N-([1,1'-Biphenyl]-4-ylmethyl)-4-ethoxyaniline
CAS 356530-22-8C21H21NO
N-([1,1'-Biphenyl]-4-ylmethyl)-2,3-dimethylaniline chemical structure, C21H21N, CAS 1040682-43-6
N-([1,1'-Biphenyl]-4-ylmethyl)-2,3-dimethylaniline
CAS 1040682-43-6C21H21N
N-([1,1'-Biphenyl]-4-ylmethyl)-2-methoxyaniline chemical structure, C20H19NO, CAS 1040683-67-7
N-([1,1'-Biphenyl]-4-ylmethyl)-2-methoxyaniline
CAS 1040683-67-7C20H19NO
N-([1,1'-Biphenyl]-4-ylmethyl)-4-(isopentyloxy)-aniline chemical structure, C24H27NO, CAS 1040688-78-5
N-([1,1'-Biphenyl]-4-ylmethyl)-4-(isopentyloxy)-aniline
CAS 1040688-78-5C24H27NO
N-([1,1'-Biphenyl]-4-ylmethyl)-2-butoxyaniline chemical structure, C23H25NO, CAS 1040689-07-3
N-([1,1'-Biphenyl]-4-ylmethyl)-2-butoxyaniline
CAS 1040689-07-3C23H25NO
N-(2-Iodophenyl)[1,1'-biphenyl]-4-methanamine chemical structure, C19H16IN, CAS 1040017-81-9
N-(2-Iodophenyl)[1,1'-biphenyl]-4-methanamine
CAS 1040017-81-9C19H16IN
Cay10583 chemical structure, C25H25NO3, CAS 862891-27-8
Cay10583
CAS 862891-27-8C25H25NO3