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Murcko scaffold

4-Cyclobutylpyrimidine scaffold

133 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
133
With full pages
3
Scaffold SMILES

c1cc(C2CCC2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Cyclobutylpyrimidine page
Murcko scaffold c1cc(C2CCC2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 133 chemicals

4-Pyrimidinecarbonitrile, 6-(1-hydroxy-3-methylcyclobutyl)-, trans- chemical structure, C10H11N3O, CAS 155806-85-2
4-Pyrimidinecarbonitrile, 6-(1-hydroxy-3-methylcyclobutyl)-, trans-
CAS 155806-85-2C10H11N3O
4-Chloro-6-cyclobutylpyrimidin-2-amine chemical structure, C8H10ClN3, CAS 199863-85-9
4-Chloro-6-cyclobutylpyrimidin-2-amine
CAS 199863-85-9C8H10ClN3
4-Bromo-6-cyclobutylpyrimidine chemical structure, C8H9BrN2, CAS 1086382-15-1
4-Bromo-6-cyclobutylpyrimidine
CAS 1086382-15-1C8H9BrN2
4-Chloro-6-cyclobutylpyrimidine chemical structure, C8H9ClN2, CAS 768397-43-9
4-Chloro-6-cyclobutylpyrimidine
CAS 768397-43-9C8H9ClN2
2-Bromo-4-(cyclobutyl)pyrimidine chemical structure, C8H9BrN2, CAS 1215071-26-3
2-Bromo-4-(cyclobutyl)pyrimidine
CAS 1215071-26-3C8H9BrN2
4-Cyclobutylpyrimidin-2-amine chemical structure, C8H11N3, CAS 1215073-20-3
4-Cyclobutylpyrimidin-2-amine
CAS 1215073-20-3C8H11N3
2-Chloro-4-cyclobutylpyrimidine chemical structure, C8H9ClN2, CAS 1215072-90-4
2-Chloro-4-cyclobutylpyrimidine
CAS 1215072-90-4C8H9ClN2
4-Cyclobutyl-2-(methylthio)pyrimidine-5-carboxylic acid chemical structure, C10H12N2O2S, CAS 1191095-45-0
4-Cyclobutyl-2-(methylthio)pyrimidine-5-carboxylic acid
CAS 1191095-45-0C10H12N2O2S
Methyl 4-cyclobutyl-2-(methylthio)pyrimidine-5-carboxylate chemical structure, C11H14N2O2S, CAS 1191095-44-9
Methyl 4-cyclobutyl-2-(methylthio)pyrimidine-5-carboxylate
CAS 1191095-44-9C11H14N2O2S
Methyl 4-cyclobutyl-2-(methylsulfonyl)pyrimidine-5-carboxylate chemical structure, C11H14N2O4S, CAS 1292289-41-8
Methyl 4-cyclobutyl-2-(methylsulfonyl)pyrimidine-5-carboxylate
CAS 1292289-41-8C11H14N2O4S
2,4-Dichloro-6-cyclobutylpyrimidine chemical structure, C8H8Cl2N2, CAS 1353853-74-3
2,4-Dichloro-6-cyclobutylpyrimidine
CAS 1353853-74-3C8H8Cl2N2
2-Chloro-4-amino-6-(cyclobutyl)pyrimidine chemical structure, C8H10ClN3, CAS 1353855-86-3
2-Chloro-4-amino-6-(cyclobutyl)pyrimidine
CAS 1353855-86-3C8H10ClN3
4-Cyclobutylpyrimidine chemical structure, C8H10N2, CAS 2138095-54-0
4-Cyclobutylpyrimidine
CAS 2138095-54-0C8H10N2
Ethyl 6-cyclobutyl-2-(trifluoromethyl)pyrimidine-4-carboxylate chemical structure, C12H13F3N2O2, CAS 1379375-61-7
Ethyl 6-cyclobutyl-2-(trifluoromethyl)pyrimidine-4-carboxylate
CAS 1379375-61-7C12H13F3N2O2
4-Cyclobutyl-2-(methylsulfonyl)pyrimidine-5-carboxylic acid chemical structure, C10H12N2O4S, CAS 1956332-08-3
4-Cyclobutyl-2-(methylsulfonyl)pyrimidine-5-carboxylic acid
CAS 1956332-08-3C10H12N2O4S
6-Cyclobutyl-2-methylpyrimidine-4-carboxylic acid chemical structure, C10H12N2O2, CAS 1780150-89-1
6-Cyclobutyl-2-methylpyrimidine-4-carboxylic acid
CAS 1780150-89-1C10H12N2O2
6-Cyclobutylpyrimidine-4-carboxylic acid chemical structure, C9H10N2O2, CAS 1781761-88-3
6-Cyclobutylpyrimidine-4-carboxylic acid
CAS 1781761-88-3C9H10N2O2
1-(Pyrimidin-4-yl)cyclobutane-1-carboxylic acid chemical structure, C9H10N2O2, CAS 1427023-36-6
1-(Pyrimidin-4-yl)cyclobutane-1-carboxylic acid
CAS 1427023-36-6C9H10N2O2
(6-Cyclobutylpyrimidin-4-yl)methanamine chemical structure, C9H13N3, CAS 1782200-40-1
(6-Cyclobutylpyrimidin-4-yl)methanamine
CAS 1782200-40-1C9H13N3
1-(Pyrimidin-4-yl)cyclobutan-1-amine chemical structure, C8H11N3, CAS 1427023-49-1
1-(Pyrimidin-4-yl)cyclobutan-1-amine
CAS 1427023-49-1C8H11N3
1-[1-(Pyrimidin-4-yl)cyclobutyl]methanamine chemical structure, C9H13N3, CAS 1506284-95-2
1-[1-(Pyrimidin-4-yl)cyclobutyl]methanamine
CAS 1506284-95-2C9H13N3
(1-(6-Methylpyrimidin-4-yl)cyclobutyl)methanamine chemical structure, C10H15N3, CAS 1536544-10-1
(1-(6-Methylpyrimidin-4-yl)cyclobutyl)methanamine
CAS 1536544-10-1C10H15N3
6-Cyclobutylpyrimidin-4-amine chemical structure, C8H11N3, CAS 1557338-24-5
6-Cyclobutylpyrimidin-4-amine
CAS 1557338-24-5C8H11N3
6-Cyclobutyl-2-methylpyrimidin-4-amine chemical structure, C9H13N3, CAS 1412954-95-0
6-Cyclobutyl-2-methylpyrimidin-4-amine
CAS 1412954-95-0C9H13N3