CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 10 atoms

166 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
166
With full pages
23
Scaffold SMILES

c1csc(-c2cscn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-c2cscn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 166 chemicals

N-[4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]butanamide chemical structure, C11H11ClN2OS2, CAS 392248-58-7
N-[4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]butanamide
CAS 392248-58-7C11H11ClN2OS2
1-(4-(5-Methylthiophen-2-yl)thiazol-2-yl)ethan-1-amine chemical structure, C10H12N2S2, CAS 642931-50-8
1-(4-(5-Methylthiophen-2-yl)thiazol-2-yl)ethan-1-amine
CAS 642931-50-8C10H12N2S2
N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide chemical structure, C10H10ClN3S2, CAS 478260-66-1
N'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-N,N-dimethylmethanimidamide
CAS 478260-66-1C10H10ClN3S2
4-(5-Ethyl-thiophen-2-yl)-5-methyl-thiazol-2-ylamine chemical structure, C10H12N2S2, CAS 781574-99-0
4-(5-Ethyl-thiophen-2-yl)-5-methyl-thiazol-2-ylamine
CAS 781574-99-0C10H12N2S2
5-Ethyl-4-thiophen-2-yl-thiazol-2-ylamine chemical structure, C9H10N2S2, CAS 883540-59-8
5-Ethyl-4-thiophen-2-yl-thiazol-2-ylamine
CAS 883540-59-8C9H10N2S2
N-{2-[5-(2-Amino-1,3-thiazol-4-yl)thiophen-2-yl]ethyl}acetamide chemical structure, C11H13N3OS2, CAS 874623-13-9
N-{2-[5-(2-Amino-1,3-thiazol-4-yl)thiophen-2-yl]ethyl}acetamide
CAS 874623-13-9C11H13N3OS2
[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl]methanamine chemical structure, C9H10N2S2, CAS 868238-07-7
[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl]methanamine
CAS 868238-07-7C9H10N2S2
4-{[4-(5-Methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoic acid chemical structure, C12H14N2O2S2, CAS 871217-36-6
4-{[4-(5-Methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoic acid
CAS 871217-36-6C12H14N2O2S2
2-[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl]ethan-1-amine chemical structure, C10H12N2S2, CAS 885526-68-1
2-[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl]ethan-1-amine
CAS 885526-68-1C10H12N2S2
2-Hydrazinyl-5-methyl-4-(thiophen-2-yl)thiazole chemical structure, C8H9N3S2, CAS 886494-13-9
2-Hydrazinyl-5-methyl-4-(thiophen-2-yl)thiazole
CAS 886494-13-9C8H9N3S2
2-Hydrazinyl-4-(thiophen-2-yl)thiazole chemical structure, C7H7N3S2, CAS 21036-68-0
2-Hydrazinyl-4-(thiophen-2-yl)thiazole
CAS 21036-68-0C7H7N3S2
(Z)-3-Methyl-4-oxo-4-((4-(thiophen-2-yl)thiazol-2-yl)amino)but-2-enoic acid chemical structure, C12H10N2O3S2, CAS 886131-90-4
(Z)-3-Methyl-4-oxo-4-((4-(thiophen-2-yl)thiazol-2-yl)amino)but-2-enoic acid
CAS 886131-90-4C12H10N2O3S2
N-{[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl]methyl}acetamide chemical structure, C11H12N2OS2, CAS 878222-29-8
N-{[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl]methyl}acetamide
CAS 878222-29-8C11H12N2OS2
Arotinolol impurity 30 chemical structure, C15H21ClN2O3S3, CAS 104766-23-6
Arotinolol impurity 30
CAS 104766-23-6C15H21ClN2O3S3
Arotinolol impurity 62 chemical structure, C15H20N2O3S3, CAS 52560-88-0
Arotinolol impurity 62
CAS 52560-88-0C15H20N2O3S3
Arotinolol, (R)- chemical structure, C15H21N3O2S3, CAS 92075-58-6
Arotinolol, (R)-
CAS 92075-58-6C15H21N3O2S3
Arotinolol, (S)- chemical structure, C15H21N3O2S3, CAS 139332-61-9
Arotinolol, (S)-
CAS 139332-61-9C15H21N3O2S3
5-Bromo-4-(thiophen-2-yl)thiazol-2-amine chemical structure, C7H5BrN2S2, CAS 81216-84-4
5-Bromo-4-(thiophen-2-yl)thiazol-2-amine
CAS 81216-84-4C7H5BrN2S2
4-(4-Bromothiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C7H5BrN2S2, CAS 81216-89-9
4-(4-Bromothiophen-2-yl)-1,3-thiazol-2-amine
CAS 81216-89-9C7H5BrN2S2
N-[4-(2-Thienyl)-1,3-thiazol-2-yl]guanidine chemical structure, C8H8N4S2, CAS 735225-85-1
N-[4-(2-Thienyl)-1,3-thiazol-2-yl]guanidine
CAS 735225-85-1C8H8N4S2
2-[4-(Thiophen-2-yl)-1,3-thiazol-5-yl]acetic acid chemical structure, C9H7NO2S2, CAS 927999-28-8
2-[4-(Thiophen-2-yl)-1,3-thiazol-5-yl]acetic acid
CAS 927999-28-8C9H7NO2S2
2-(2-Acetamido-4-(thiophen-2-yl)thiazol-5-yl)acetic acid chemical structure, C11H10N2O3S2, CAS 927999-29-9
2-(2-Acetamido-4-(thiophen-2-yl)thiazol-5-yl)acetic acid
CAS 927999-29-9C11H10N2O3S2
3-[2-Methyl-4-(2-thienyl)-1,3-thiazol-5-yl]propanoic acid chemical structure, C11H11NO2S2, CAS 927999-37-9
3-[2-Methyl-4-(2-thienyl)-1,3-thiazol-5-yl]propanoic acid
CAS 927999-37-9C11H11NO2S2
3-[2-Amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]propanoic acid chemical structure, C10H10N2O2S2, CAS 301330-60-9
3-[2-Amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]propanoic acid
CAS 301330-60-9C10H10N2O2S2