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Murcko scaffold

Ring system with 2 rings and 10 atoms

166 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
166
With full pages
23
Scaffold SMILES

c1csc(-c2cscn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-c2cscn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 166 of 166 chemicals

Methyl 2-[2-amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetate chemical structure, C10H10N2O2S2, CAS 1879204-57-5
Methyl 2-[2-amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetate
CAS 1879204-57-5C10H10N2O2S2
Methyl 5-(2-amino-1,3-thiazol-4-yl)thiophene-3-carboxylate chemical structure, C9H8N2O2S2, CAS 2229175-08-8
Methyl 5-(2-amino-1,3-thiazol-4-yl)thiophene-3-carboxylate
CAS 2229175-08-8C9H8N2O2S2
4-(3-Bromo-4-methylthiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C8H7BrN2S2, CAS 2229335-92-4
4-(3-Bromo-4-methylthiophen-2-yl)-1,3-thiazol-2-amine
CAS 2229335-92-4C8H7BrN2S2
5-(2-Amino-1,3-thiazol-4-yl)thiophene-3-carbonitrile chemical structure, C8H5N3S2, CAS 2229267-80-3
5-(2-Amino-1,3-thiazol-4-yl)thiophene-3-carbonitrile
CAS 2229267-80-3C8H5N3S2
Methyl 4-{[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoate chemical structure, C13H16N2O2S2, CAS 2639433-72-8
Methyl 4-{[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoate
CAS 2639433-72-8C13H16N2O2S2
tert-Butyl 4-{[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoate chemical structure, C16H22N2O2S2, CAS 2639409-15-5
tert-Butyl 4-{[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoate
CAS 2639409-15-5C16H22N2O2S2
2-(5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl)ethan-1-amine dihydrochloride chemical structure, C10H14Cl2N2S2, CAS 2866334-24-7
2-(5-(2-Methyl-1,3-thiazol-4-yl)thiophen-2-yl)ethan-1-amine dihydrochloride
CAS 2866334-24-7C10H14Cl2N2S2
Ethyl 2-{5-[2-(methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetate chemical structure, C12H14N2O2S2, CAS 2639404-70-7
Ethyl 2-{5-[2-(methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetate
CAS 2639404-70-7C12H14N2O2S2
tert-Butyl 2-[2-amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetate chemical structure, C13H16N2O2S2, CAS 2639459-30-4
tert-Butyl 2-[2-amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetate
CAS 2639459-30-4C13H16N2O2S2
2-[5-(2-{[(tert-Butoxy)carbonyl](methyl)amino}-1,3-thiazol-4-yl)thiophen-2-yl]acetic acid chemical structure, C15H18N2O4S2, CAS 2639424-80-7
2-[5-(2-{[(tert-Butoxy)carbonyl](methyl)amino}-1,3-thiazol-4-yl)thiophen-2-yl]acetic acid
CAS 2639424-80-7C15H18N2O4S2
tert-Butyl 2-{5-[2-(methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetate chemical structure, C14H18N2O2S2, CAS 2639410-09-4
tert-Butyl 2-{5-[2-(methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetate
CAS 2639410-09-4C14H18N2O2S2
Ethyl 4-{[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoate chemical structure, C14H18N2O2S2, CAS 2639439-08-8
Ethyl 4-{[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoate
CAS 2639439-08-8C14H18N2O2S2
2-[4-(Thiophen-2-yl)-2-(2,2,2-trifluoroacetamido)-1,3-thiazol-5-yl]acetic acid chemical structure, C11H7F3N2O3S2, CAS 2680768-67-4
2-[4-(Thiophen-2-yl)-2-(2,2,2-trifluoroacetamido)-1,3-thiazol-5-yl]acetic acid
CAS 2680768-67-4C11H7F3N2O3S2
2-{5-[2-(N-Methylacetamido)-1,3-thiazol-4-yl]thiophen-2-yl}acetic acid chemical structure, C12H12N2O3S2, CAS 2680716-57-6
2-{5-[2-(N-Methylacetamido)-1,3-thiazol-4-yl]thiophen-2-yl}acetic acid
CAS 2680716-57-6C12H12N2O3S2
tert-Butyl N-[4-(4-bromothiophen-2-yl)-1,3-thiazol-2-yl]carbamate chemical structure, C12H13BrN2O2S2, CAS 2680867-58-5
tert-Butyl N-[4-(4-bromothiophen-2-yl)-1,3-thiazol-2-yl]carbamate
CAS 2680867-58-5C12H13BrN2O2S2
2-{5-[2-(2,2,2-Trifluoro-N-methylacetamido)-1,3-thiazol-4-yl]thiophen-2-yl}acetic acid chemical structure, C12H9F3N2O3S2, CAS 2680798-20-1
2-{5-[2-(2,2,2-Trifluoro-N-methylacetamido)-1,3-thiazol-4-yl]thiophen-2-yl}acetic acid
CAS 2680798-20-1C12H9F3N2O3S2
4-{[(tert-Butoxy)carbonyl][4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoic acid chemical structure, C17H22N2O4S2, CAS 2680744-93-6
4-{[(tert-Butoxy)carbonyl][4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoic acid
CAS 2680744-93-6C17H22N2O4S2
tert-Butyl N-[4-(5-bromothiophen-2-yl)-1,3-thiazol-2-yl]carbamate chemical structure, C12H13BrN2O2S2, CAS 2680721-86-0
tert-Butyl N-[4-(5-bromothiophen-2-yl)-1,3-thiazol-2-yl]carbamate
CAS 2680721-86-0C12H13BrN2O2S2
tert-Butyl N-[4-(3-bromothiophen-2-yl)-1,3-thiazol-2-yl]carbamate chemical structure, C12H13BrN2O2S2, CAS 2680891-57-8
tert-Butyl N-[4-(3-bromothiophen-2-yl)-1,3-thiazol-2-yl]carbamate
CAS 2680891-57-8C12H13BrN2O2S2
4-{2,2,2-Trifluoro-N-[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]acetamido}butanoic acid chemical structure, C14H13F3N2O3S2, CAS 2680689-54-5
4-{2,2,2-Trifluoro-N-[4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]acetamido}butanoic acid
CAS 2680689-54-5C14H13F3N2O3S2
Methyl 2-{5-[2-(methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetate chemical structure, C11H12N2O2S2, CAS 1996354-88-1
Methyl 2-{5-[2-(methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetate
CAS 1996354-88-1C11H12N2O2S2
2-(2-{[(Prop-2-en-1-yloxy)carbonyl]amino}-4-(thiophen-2-yl)-1,3-thiazol-5-yl)acetic acid chemical structure, C13H12N2O4S2, CAS 2763907-07-7
2-(2-{[(Prop-2-en-1-yloxy)carbonyl]amino}-4-(thiophen-2-yl)-1,3-thiazol-5-yl)acetic acid
CAS 2763907-07-7C13H12N2O4S2