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Murcko scaffold

Ring system with 2 rings and 10 atoms

166 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
166
With full pages
23
Scaffold SMILES

c1csc(-c2cscn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-c2cscn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 166 chemicals

1-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-3-(2-methoxyethyl)urea chemical structure, C11H12ClN3O2S2, CAS 1226428-90-5
1-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-3-(2-methoxyethyl)urea
CAS 1226428-90-5C11H12ClN3O2S2
1-[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-3-yl]ethan-1-one chemical structure, C10H9NOS2, CAS 1258651-53-4
1-[5-(2-Methyl-1,3-thiazol-4-yl)thiophen-3-yl]ethan-1-one
CAS 1258651-53-4C10H9NOS2
Methyl 5-(2-aminothiazol-4-yl)thiophene-2-carboxylate chemical structure, C9H8N2O2S2, CAS 960511-21-1
Methyl 5-(2-aminothiazol-4-yl)thiophene-2-carboxylate
CAS 960511-21-1C9H8N2O2S2
4-(3-Methylthiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C8H8N2S2, CAS 136382-16-6
4-(3-Methylthiophen-2-yl)-1,3-thiazol-2-amine
CAS 136382-16-6C8H8N2S2
2-Chloro-4-(5-methylthiophen-2-yl)-1,3-thiazole chemical structure, C8H6ClNS2, CAS 1343463-13-7
2-Chloro-4-(5-methylthiophen-2-yl)-1,3-thiazole
CAS 1343463-13-7C8H6ClNS2
2-{5-[2-(Methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetic acid chemical structure, C10H10N2O2S2, CAS 1339074-00-8
2-{5-[2-(Methylamino)-1,3-thiazol-4-yl]thiophen-2-yl}acetic acid
CAS 1339074-00-8C10H10N2O2S2
4-(3-Bromo-5-methylthiophen-2-yl)thiazol-2-amine chemical structure, C8H7BrN2S2, CAS 1484385-66-1
4-(3-Bromo-5-methylthiophen-2-yl)thiazol-2-amine
CAS 1484385-66-1C8H7BrN2S2
Arotinolol hydrochloride, (S)- chemical structure, C15H22ClN3O2S3, CAS 101540-26-5
Arotinolol hydrochloride, (S)-
CAS 101540-26-5C15H22ClN3O2S3
2-Chloro-4-(3-nitrothiophen-2-yl)thiazole chemical structure, C7H3ClN2O2S2, CAS 1239463-59-2
2-Chloro-4-(3-nitrothiophen-2-yl)thiazole
CAS 1239463-59-2C7H3ClN2O2S2
2-(Thiazol-4-yl)thiophen-3-amine chemical structure, C7H6N2S2, CAS 1239463-51-4
2-(Thiazol-4-yl)thiophen-3-amine
CAS 1239463-51-4C7H6N2S2
2-(2-Chlorothiazol-4-yl)thiophen-3-amine chemical structure, C7H5ClN2S2, CAS 1239463-60-5
2-(2-Chlorothiazol-4-yl)thiophen-3-amine
CAS 1239463-60-5C7H5ClN2S2
2-Methoxy-4-(3-nitrothiophen-2-yl)thiazole chemical structure, C8H6N2O3S2, CAS 1239463-56-9
2-Methoxy-4-(3-nitrothiophen-2-yl)thiazole
CAS 1239463-56-9C8H6N2O3S2
2-(2-Methoxythiazol-4-yl)thiophen-3-amine chemical structure, C8H8N2OS2, CAS 1239463-57-0
2-(2-Methoxythiazol-4-yl)thiophen-3-amine
CAS 1239463-57-0C8H8N2OS2
4-(3-Nitrothiophen-2-yl)thiazole chemical structure, C7H4N2O2S2, CAS 1239463-50-3
4-(3-Nitrothiophen-2-yl)thiazole
CAS 1239463-50-3C7H4N2O2S2
2-Methyl-4-(5-nitrothiophen-2-yl)-1,3-thiazole chemical structure, C8H6N2O2S2, CAS 62672-03-1
2-Methyl-4-(5-nitrothiophen-2-yl)-1,3-thiazole
CAS 62672-03-1C8H6N2O2S2
2-Methyl-4-(4-nitrothiophen-2-yl)-1,3-thiazole chemical structure, C8H6N2O2S2, CAS 62672-02-0
2-Methyl-4-(4-nitrothiophen-2-yl)-1,3-thiazole
CAS 62672-02-0C8H6N2O2S2
4-(4-Methylthiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C8H8N2S2, CAS 570407-14-6
4-(4-Methylthiophen-2-yl)-1,3-thiazol-2-amine
CAS 570407-14-6C8H8N2S2
4-(4-Methylthiophen-2-yl)thiazol-2-amine hydrochloride chemical structure, C8H9ClN2S2, CAS 2034528-39-5
4-(4-Methylthiophen-2-yl)thiazol-2-amine hydrochloride
CAS 2034528-39-5C8H9ClN2S2
5-(2-Aminothiazol-4-yl)thiophene-2-carbonitrile chemical structure, C8H5N3S2, CAS 1414958-61-4
5-(2-Aminothiazol-4-yl)thiophene-2-carbonitrile
CAS 1414958-61-4C8H5N3S2
Arotinolol hydrochloride, (R)- chemical structure, C15H22ClN3O2S3, CAS 87055-50-3
Arotinolol hydrochloride, (R)-
CAS 87055-50-3C15H22ClN3O2S3
4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine chemical structure, C7H4BrClN2S2, CAS 1534575-19-3
4-(5-Bromo-4-chlorothiophen-2-yl)thiazol-2-amine
CAS 1534575-19-3C7H4BrClN2S2
5-Bromo-4-(2-thienyl)thiazole chemical structure, C7H4BrNS2, CAS 1267279-03-7
5-Bromo-4-(2-thienyl)thiazole
CAS 1267279-03-7C7H4BrNS2
5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine chemical structure, C7H4BrClN2S2, CAS 1268118-96-2
5-Bromo-4-(5-chlorothiophen-2-yl)thiazol-2-amine
CAS 1268118-96-2C7H4BrClN2S2
Ethyl 2-[2-amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetate chemical structure, C11H12N2O2S2, CAS 685563-46-6
Ethyl 2-[2-amino-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetate
CAS 685563-46-6C11H12N2O2S2