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Murcko scaffold

Ring system with 2 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(CC1SC=NC1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC1SC=NC1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-(2-Imino-4-oxothiazolidin-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C12H10F3N3O2S, CAS 308294-69-1
2-(2-Imino-4-oxothiazolidin-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 308294-69-1C12H10F3N3O2S
2-Amino-N-(4-chlorophenyl)-4,5-dihydro-4-oxo-5-thiazoleacetamide chemical structure, C11H10ClN3O2S, CAS 54819-75-9
2-Amino-N-(4-chlorophenyl)-4,5-dihydro-4-oxo-5-thiazoleacetamide
CAS 54819-75-9C11H10ClN3O2S
4-{[(2-Amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetyl]amino}benzoic acid chemical structure, C12H11N3O4S, CAS 101413-78-9
4-{[(2-Amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetyl]amino}benzoic acid
CAS 101413-78-9C12H11N3O4S
N-(2-Ethylphenyl)-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C13H15N3O2S, CAS 497090-49-0
N-(2-Ethylphenyl)-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide
CAS 497090-49-0C13H15N3O2S
N-{4-[(Difluoromethyl)sulfanyl]phenyl}-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C12H11F2N3O2S2, CAS 514182-01-5
N-{4-[(Difluoromethyl)sulfanyl]phenyl}-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide
CAS 514182-01-5C12H11F2N3O2S2
Ethyl 4-(2-(2-imino-4-oxothiazolidin-5-yl)acetamido)benzoate chemical structure, C14H15N3O4S, CAS 6148-38-5
Ethyl 4-(2-(2-imino-4-oxothiazolidin-5-yl)acetamido)benzoate
CAS 6148-38-5C14H15N3O4S
2-(2-Imino-4-oxothiazolidin-5-yl)-N-(m-tolyl)acetamide chemical structure, C12H13N3O2S, CAS 311327-03-4
2-(2-Imino-4-oxothiazolidin-5-yl)-N-(m-tolyl)acetamide
CAS 311327-03-4C12H13N3O2S
2-(2-Imino-4-oxo-1,3-thiazolidin-5-yl)-N-phenylacetamide chemical structure, C11H11N3O2S, CAS 138375-99-2
2-(2-Imino-4-oxo-1,3-thiazolidin-5-yl)-N-phenylacetamide
CAS 138375-99-2C11H11N3O2S
3-{2-[2-(Diethylamino)-4-oxo-4,5-dihydro-1,3-thiazol-5-yl]acetamido}benzoic acid chemical structure, C16H19N3O4S, CAS 749902-44-1
3-{2-[2-(Diethylamino)-4-oxo-4,5-dihydro-1,3-thiazol-5-yl]acetamido}benzoic acid
CAS 749902-44-1C16H19N3O4S
3-[2-(2-Amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamido]benzoic acid chemical structure, C12H11N3O4S, CAS 101413-79-0
3-[2-(2-Amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamido]benzoic acid
CAS 101413-79-0C12H11N3O4S
N-(2-Cyanophenyl)-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C12H10N4O2S, CAS 496011-20-2
N-(2-Cyanophenyl)-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide
CAS 496011-20-2C12H10N4O2S
2-(2-Imino-4-oxothiazolidin-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide chemical structure, C12H10F3N3O3S, CAS 881483-29-0
2-(2-Imino-4-oxothiazolidin-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide
CAS 881483-29-0C12H10F3N3O3S