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Murcko scaffold

2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-phenylacetamide scaffold

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
14
With full pages
6
Scaffold SMILES

O=C(CC1SC(=O)N(c2ccccc2)C1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-phenylacetamide page
Murcko scaffold O=C(CC1SC(=O)N(c2ccccc2)C1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-phenylacetamide chemical structure, C17H14N2O3S, CAS 488794-67-8
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-phenylacetamide
CAS 488794-67-8C17H14N2O3S
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(2-methylphenyl)acetamide chemical structure, C18H16N2O3S, CAS 453579-03-8
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(2-methylphenyl)acetamide
CAS 453579-03-8C18H16N2O3S
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-methylphenyl)acetamide chemical structure, C18H16N2O3S, CAS 453579-07-2
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-methylphenyl)acetamide
CAS 453579-07-2C18H16N2O3S
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide chemical structure, C19H18N2O4S, CAS 453578-98-8
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide
CAS 453578-98-8C19H18N2O4S
N-(4-Chlorophenyl)-2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)acetamide chemical structure, C17H13ClN2O3S, CAS 405916-21-4
N-(4-Chlorophenyl)-2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)acetamide
CAS 405916-21-4C17H13ClN2O3S
Ethyl 4-{[(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)acetyl]amino}benzoate chemical structure, C20H18N2O5S, CAS 453579-10-7
Ethyl 4-{[(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)acetyl]amino}benzoate
CAS 453579-10-7C20H18N2O5S
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-iodophenyl)acetamide chemical structure, C17H13IN2O3S, CAS 487033-94-3
2-(2,4-Dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-iodophenyl)acetamide
CAS 487033-94-3C17H13IN2O3S
N-(4-Bromophenyl)-2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)acetamide chemical structure, C17H13BrN2O3S, CAS 488108-01-6
N-(4-Bromophenyl)-2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)acetamide
CAS 488108-01-6C17H13BrN2O3S
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-(4-methylphenyl)acetamide chemical structure, C18H15FN2O3S, CAS 929473-90-5
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-(4-methylphenyl)acetamide
CAS 929473-90-5C18H15FN2O3S
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-(2-methylphenyl)acetamide chemical structure, C18H15FN2O3S, CAS 929413-12-7
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-(2-methylphenyl)acetamide
CAS 929413-12-7C18H15FN2O3S
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-phenylacetamide chemical structure, C17H13FN2O3S, CAS 929372-53-2
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-phenylacetamide
CAS 929372-53-2C17H13FN2O3S
N-(4-Fluorophenyl)-2-[3-(4-fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C17H12F2N2O3S, CAS 929473-92-7
N-(4-Fluorophenyl)-2-[3-(4-fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]acetamide
CAS 929473-92-7C17H12F2N2O3S
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-(3-methylphenyl)acetamide chemical structure, C18H15FN2O3S, CAS 924829-15-2
2-[3-(4-Fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]-N-(3-methylphenyl)acetamide
CAS 924829-15-2C18H15FN2O3S
N-(4-Ethoxyphenyl)-2-[3-(4-fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C19H17FN2O4S, CAS 924829-17-4
N-(4-Ethoxyphenyl)-2-[3-(4-fluorophenyl)-2,4-dioxo-1,3-thiazolidin-5-yl]acetamide
CAS 924829-17-4C19H17FN2O4S