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Murcko scaffold

Ring system with 2 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
7
With full pages
6
Scaffold SMILES

O=C(COC(=O)CCc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)CCc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

[2-[N-(2-Cyanoethyl)anilino]-2-oxoethyl] 3-phenylpropanoate chemical structure, C20H20N2O3, CAS 380173-55-7
[2-[N-(2-Cyanoethyl)anilino]-2-oxoethyl] 3-phenylpropanoate
CAS 380173-55-7C20H20N2O3
[2-(2-Chloro-4-methylanilino)-2-oxoethyl] 3-phenylpropanoate chemical structure, C18H18ClNO3, CAS 389815-70-7
[2-(2-Chloro-4-methylanilino)-2-oxoethyl] 3-phenylpropanoate
CAS 389815-70-7C18H18ClNO3
[2-(N-Ethylanilino)-2-oxoethyl] 3-phenylpropanoate chemical structure, C19H21NO3, CAS 380198-64-1
[2-(N-Ethylanilino)-2-oxoethyl] 3-phenylpropanoate
CAS 380198-64-1C19H21NO3
[2-(2-Methylsulfanylanilino)-2-oxoethyl] 3-phenylpropanoate chemical structure, C18H19NO3S, CAS 731792-74-8
[2-(2-Methylsulfanylanilino)-2-oxoethyl] 3-phenylpropanoate
CAS 731792-74-8C18H19NO3S
[2-(2,4-Dimethoxyanilino)-2-oxoethyl] 3-phenylpropanoate chemical structure, C19H21NO5, CAS 728927-22-8
[2-(2,4-Dimethoxyanilino)-2-oxoethyl] 3-phenylpropanoate
CAS 728927-22-8C19H21NO5
[2-(2-Chloro-4-fluoroanilino)-2-oxoethyl] 3-phenylpropanoate chemical structure, C17H15ClFNO3, CAS 389815-00-3
[2-(2-Chloro-4-fluoroanilino)-2-oxoethyl] 3-phenylpropanoate
CAS 389815-00-3C17H15ClFNO3
1-((4-Carbamoylphenyl)amino)-1-oxopropan-2-yl 3-phenylpropanoate chemical structure, C19H20N2O4, CAS 930699-88-0
1-((4-Carbamoylphenyl)amino)-1-oxopropan-2-yl 3-phenylpropanoate
CAS 930699-88-0C19H20N2O4