CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
9
With full pages
2
Scaffold SMILES

O=C(C=Cc1ccc2c(c1)C=CCO2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc2c(c1)C=CCO2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-(3-(3-Methyl-2-butenyl)-2,4-(dihydroxy)phenyl)-3-(2,2-dimethyl-8-hydroxy-2H-benzopyran-6-yl)-2-propen-1-one chemical structure, C25H26O5, CAS 151135-83-0
1-(3-(3-Methyl-2-butenyl)-2,4-(dihydroxy)phenyl)-3-(2,2-dimethyl-8-hydroxy-2H-benzopyran-6-yl)-2-propen-1-one
CAS 151135-83-0C25H26O5
Licoagrochalcone B chemical structure, C21H20O4, CAS 325144-67-0
Licoagrochalcone B
CAS 325144-67-0C21H20O4
Sophoradochromene chemical structure, C30H34O4, CAS 23057-58-1
Sophoradochromene
CAS 23057-58-1C30H34O4
Praecanson A chemical structure, C23H24O5, CAS 74517-76-3
Praecanson A
CAS 74517-76-3C23H24O5
Kanzonol B chemical structure, C20H18O4, CAS 155233-19-5
Kanzonol B
CAS 155233-19-5C20H18O4
Paratocarpin C chemical structure, C25H26O4, CAS 161099-58-7
Paratocarpin C
CAS 161099-58-7C25H26O4
Anthyllisone chemical structure, C25H26O4, CAS 178734-43-5
Anthyllisone
CAS 178734-43-5C25H26O4
Abyssinone A chemical structure, C20H18O5, CAS 1039071-39-0
Abyssinone A
CAS 1039071-39-0C20H18O5
(E)-2'-Methoxy-6'',6''-dimethylchromeno-[2'',3'':4',3']-9-methoxychalcone chemical structure, C22H22O4, CAS 179003-95-3
(E)-2'-Methoxy-6'',6''-dimethylchromeno-[2'',3'':4',3']-9-methoxychalcone
CAS 179003-95-3C22H22O4